Sarcomatoid Hepatocellular Carcinoma A Case Report and Review of the Differential Diagnosis of Malignant Spindle Cell Lesions of the LiverStashek, Kristen M., MD*; White, Rachel, MD*; Song, Linda, MD*; Tondon, Rashmi, MD†; Kallen, Michael, MD*; Twaddell, William, MD*AJSP: Reviews & Reports: January/February 2019 - Volume 24 - Issue 1 - p 27–30 doi: 10.1097/PCR.0000000000000293 Case Reports Buy SDC Abstract Author InformationAuthors Article MetricsMetrics Sarcomatoid hepatocellular carcinoma is a rare aggressive variant of hepatocellular carcinoma that typically shows a conventional component of hepatocellular carcinoma admixed with a malignant spindle cell proliferation. In small biopsy specimens, the conventional component may not always be present; therefore, knowledge of the differential diagnosis of malignant spindle cell lesion presenting in the liver is necessary to ensure accurate diagnosis. From the *Department of Pathology, University of Maryland School of Medicine, Baltimore, MD; and †Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Reprints: Kristen M. Stashek, MD, Department of Pathology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201. E-mail: KStashek@som.umaryland.edu. The authors have no funding or conflicts to declare. © 2019 Lippincott Williams & Wilkins, Inc.