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Fine-Needle Aspiration Cytology of Parathyroid Lesions

Legesse, Teklu MD; Staats, Paul N. MD

doi: 10.1097/PCR.0000000000000111
Case Reviews
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Parathyroid tissue is not uncommonly encountered in evaluation of “thyroid nodules,” either due to radiologic misinterpretation of a parathyroid neoplasm as thyroidal in origin or due to incidental sampling during aspiration of a thyroid nodule. Recognition of the cytologic features of parathyroid is important to prevent misdiagnosis of these relatively common lesions and subsequent inappropriate surgical management. In addition, fine-needle aspiration is occasionally used in the preoperative workup of patients with hyperparathyroidism. Fine-needle aspiration can be used as an adjunct to imaging for preoperative localization of hyperfunctioning parathyroid tissue, which helps to minimize the extent of surgical exploration. This report reviews the cytomorphologic features of parathyroid lesions, differential diagnostic considerations, and ancillary methods that can be used to arrive at the right diagnosis.

From the University of Maryland Medical Center and University of Maryland School of Medicine, Baltimore, MD.

Reprints: Teklu Legesse, University of Maryland Medical Center and University of Maryland School of Medicine, 22 S Greene street Baltimore MD 21201. E-mail: tlegesse@umm.edu.

The authors have no funding or conflicts to declare.

Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.