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Superficially Invasive Squamous Cell Carcinoma of the Vulva and Vagina

Heller, Debra S. MD*; Colgan, Terence J. MD; Allbritton, Jill MD

doi: 10.1097/PCR.0b013e3182990fab
Case Reviews

The LAST definition of superficially invasive squamous cell carcinoma of the vulva conforms to the American Joint Committee on Cancer T1a (FIGO [International Federation of Gynecology and Obstetrics] 1A) staging, delineating a subset of early invasive lesions with minimal risk of lymph node metastasis. The diagnosis can be difficult to make histopathologically. A case of unexpected early multifocal invasion is presented that highlights the difficulties in the diagnosis of superficially invasive squamous cell carcinoma and FIGO 1A of the vulva.

From the *Departments of Pathology and Laboratory Medicine, UMDNJ–New Jersey Medical School, Newark, NJ; †Mount Sinai Hospital, Toronto, Ontario, Canada; and ‡Miraca Life Sciences, Glen Burnie, MD.

Reprints: Debra S. Heller, MD, Department of Pathology, UH-E158 UMDNJ–New Jersey Medical School, 185 S Orange Ave, Newark, NJ 07103. E-mail:

The authors have no funding or conflicts to declare.

© 2013 by Lippincott Williams & Wilkins.