Intraductal Papillary Mucinous Neoplasms, Oncocytic Type

Abstract

According to their histologic features and their mucin profile, intraductal papillary mucinous neoplasms form a group of heterogeneous cystic pancreatic neoplasms. Intraductal oncocytic papillary neoplasms constitute a rare phenotypic variant of intraductal papillary mucinous neoplasms. They correspond to a grossly visible intraductal neoplasm involving the main pancreatic duct and/or its branch ducts composed of cells with prominent oncocytic differentiation. Some scattered goblet cells are intermingled. This cellular proliferation forms complex thick papillae and frequently exhibits high-grade dysplasia. However, the prognosis after surgical resection seems usually good, as an invasive component is present in less than 20% of cases.