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Papillary Lesions of the Breast

Sheridan, Todd MD; Ioffe, Olga B. MD

doi: 10.1097/PCR.0b013e3181b6afba
Case Report

Papillary lesions of the breast remain a challenge in the practice of surgical pathology, and this difficulty is further magnified by the abundance of varying terminologies. Furthermore, the management of benign papillomas diagnosed on core needle biopsy remains controversial. This article reviews the spectrum of papillary lesions of the breast with a focus on terminology and the diagnostic features of each entity. Diagnostic pitfalls and the use of immunohistochemistry are discussed. Management of papillary lesions diagnosed on image-directed core biopsies is also reviewed.

From the Department of Pathology, University of Maryland Medical Center, Baltimore, MD.

Reprints: Olga B. Ioffe, MD, Department of Pathology, University of Maryland Medical System, 22 S. Greene St., Baltimore, MD 21201. E-mail:

© 2009 Lippincott Williams & Wilkins, Inc.