NANETS GuidelinesThe North American Neuroendocrine Tumor Society Consensus Paper on the Surgical Management of Pancreatic Neuroendocrine TumorsHowe, James R. MD*; Merchant, Nipun B. MD†; Conrad, Claudius MD, PhD‡; Keutgen, Xavier M. MD§; Hallet, Julie MD, MSc∥; Drebin, Jeffrey A. MD, PhD¶; Minter, Rebecca M. MD#; Lairmore, Terry C. MD**; Tseng, Jennifer F. MD††; Zeh, Herbert J. MD‡‡; Libutti, Steven K. MD§§; Singh, Gagandeep MD∥∥; Lee, Jeffrey E. MD¶¶; Hope, Thomas A. MD##; Kim, Michelle K. MD***; Menda, Yusuf MD†††; Halfdanarson, Thorvardur R. MD‡‡‡; Chan, Jennifer A. MD§§§; Pommier, Rodney F. MD∥∥∥Author Information From the *Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA †Department of Surgery, University of Miami, Miami, FL ‡Department of Surgery, St Elizabeth Medical Center, Tufts University School of Medicine, Boston, MA §Department of Surgery, University of Chicago Medicine, Chicago, IL ∥Department of Surgery, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Canada ¶Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY #Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI **Department of Surgery, LSU Health Sciences Center, Shreveport, LA ††Department of Surgery, Boston University Medical Center, Boston, MA ‡‡Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX §§Department of Surgery, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ ∥∥Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, CA ¶¶Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX ##Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA ***Department of Medicine, Mt Sinai Medical Center, New York, NY †††Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, IA ‡‡‡Division of Medical Oncology, Mayo Clinic Cancer Center, Rochester, MN §§§Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA ∥∥∥Department of Surgery, Oregon Health & Science University, Portland, OR. Received for publication August 24, 2019; accepted November 1, 2019. Address correspondences to: James R. Howe, MD, Department of Surgery, University of Iowa Hospitals and Clinics, 4644 JCP, 200 Hawkins Dr, Iowa City, IA 52242 (e-mail: firstname.lastname@example.org). J.R.H. has received travel expenses and/or honoraria for speaking at academic centers and at some conferences (NANETS, NANETS Regional Conferences, NETRF, NCAN, and ENETS). X.M.K. received consulting honoraria from Advanced Accelerator Applications. J.H. has received speaking honoraria from Ipsen Biopharmaceuticals Canada and Novartis Oncology, and travel support from Baxter Corporation. J.A.D. owns shares in biotech firms (ALNY and IONS) and his spouse is chief medical officer for American Regent Pharmaceuticals. R.M.M. has received travel expenses and/or honoraria for speaking at academic centers and meetings of the American Board of Surgery, National Board of Medical Examiners, Society of University Surgeons, Americas Hepatopancreatobiliary Association, International Hepatopancreatobiliary Association Fellowship Council, and Royal Australasian College of Surgeons. J.F.T. has received a research grant from Mauna Kea Technologies, Inc. H.J.Z. has received a research funding from Intuitive Surgical Inc., and travel expenses for independent symposium on robotics and HPB surgery. T.A.H. was on the advisory board and a consultant for Curium, Inc. M.K.K. received research funds from Novartis. Y.M. has received research funding from Ipsen and Advanced Accelerator Applications. T.R.H. has received research funding from Ipsen and Thermo Fisher Scientific, and has served on the advisory boards of Ipsen, Curium, Novartis, and Lexicon. J.A.C. is a consultant and advisory board member of Crinetics, Ipsen, Novartis, and Lexicon; she receives royalties from UpToDate, and owns stock in Merck. R.F.P. is a consultant to Novartis, Lexicon, and Advanced Accelerator Applications. The other authors declare no conflict of interest. Pancreas: January 2020 - Volume 49 - Issue 1 - p 1-33 doi: 10.1097/MPA.0000000000001454 Buy Metrics Abstract This manuscript is the result of the North American Neuroendocrine Tumor Society consensus conference on the surgical management of pancreatic neuroendocrine tumors from July 19 to 20, 2018. The group reviewed a series of questions of specific interest to surgeons taking care of patients with pancreatic neuroendocrine tumors, and for each, the available literature was reviewed. What follows are these reviews for each question followed by recommendations of the panel. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.