From the *Department of Pediatrics, School of Medicine, Washington University, St Louis, MO
†The Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD
Departments of ‡Biochemistry
∥Pharmacology and Medicine, Vanderbilt University, Nashville, TN
¶Institute of Cancer Research, London, United Kingdom
#Division of Gastroenterology, Hepatology, and Nutrition, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH
**Department of Radiology, University of Pittsburgh, Pittsburgh, PA
††The Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL
Departments of ‡‡Internal Medicine
§§Cell Biology, School of Medicine, Yale University, New Haven, CT
∥∥VA Connecticut Healthcare System, West Haven, CT
¶¶Knight Cancer Institute, Oregon Health and Science University, Portland, OR
##Ariel Precision Medicine, Pittsburgh, PA
***Department of Biomedical Engineering, University of Virginia, Charlottesville, VA
†††Department of Medicine
‡‡‡Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY
Departments of §§§Biomedical Data Science
∥∥∥Radiology, Stanford University, Stanford, CA
¶¶¶Institute for Systems Biology, Seattle, WA
###Deep Learning for Medical Imaging, NVIDIA Corporation, Bethesda, MD
****Proteomics Center, Boston Children's Hospital, Department of Pathology, Harvard Medical School, Boston, MA
††††Department of Pathology and Immunology, School of Medicine, Washington University, St Louis, MO
‡‡‡‡Department of Radiology and Imaging Sciences, School of Medicine, Indiana University, Indianapolis, IN
§§§§Division of Gastroenterology, Stead Family Department of Pediatrics, The University of Iowa, Iowa City, IA
∥∥∥∥Computational Medicine and Systems Medicine, Department of Digestion, Metabolism and Reproduction, Imperial College, London, United Kingdom
Departments of ¶¶¶¶Medicine
*****Physiology and Genetics, University of Pittsburgh, Pittsburgh, PA
†††††Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA.
Received for publication August 5, 2019; accepted August 8, 2019.
Address correspondence to: Aida Habtezion, MD, MSc, Division of Gastroenterology and Hepatology, Stanford University, 300 Pasteur Dr, Room M211, Stanford, CA 94305 (e-mail: firstname.lastname@example.org); or Mark E. Lowe, MD, PhD, Department of Pediatrics, School of Medicine, Washington University, 660 S Euclid Ave, MPRB 4th Floor, Campus Box 8208, St Louis, MO 63110 (e-mail: email@example.com).
This study was supported by the National Cancer Institute and National Institute of Diabetes and Digestive and Kidney Diseases under the following award numbers: U01DK108300 (A.H.), U01DK108306 (D.C.W.), UO1DK108300 (C.E.F.), U01DK108323 (T.T.), and U01DK108334 (A.U., M.E.L.). M.E.L., D.K.A., R.M.C., Z.C-M., C.E.F., F.S.G., J.W.G., K.A.K., S.K.P., H.S., S.J.S., T.T., A.U., D.C.W., and A.H. reported funding from the National Institutes of Health; M.E.L., Z.C-M., C.E.F., H.S., T.T., A.U., D.C.W., and A.H. acknowledge the support of The Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC), funded by the National Cancer Institute and the National Institute of Diabetes and Digestive and Kidney Diseases; received research support from NIHR Biomedical Research Center of Imperial College of London (V.A.K.), Research Councils of UK (J.C.), Veterans Administration (F.S.G.), Vodafone Foundation (V.A.K.), Waters Corporation (V.A.K.), Wellcome Trust (J.C.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.