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Psychological Outcomes and Quality of Life in Relation to Pancreatectomy

A Systematic Review

Lounis, Léna, MA*; Aurran-Schleinitz, Thérèse, MD†‡; Turrini, Olivier, MD§; Delpero, Jean-Robert, MD§; Bréjard, Vincent, PhD*

doi: 10.1097/MPA.0000000000001279

This review aimed to inventory and analyze previous studies regarding quality of life (QoL) and psychological outcomes in relation to pancreatectomy. PubMed and PsycInfo databases were reviewed using the Preferred Reporting Items for Systematic review and Meta-Analysis guidelines. Thirteen studies were selected, 9 of which focused on the QoL after surgery. Quality of life significantly improved 3 to 6 months after surgery. Regarding the postoperative experience, one study reported high fear of recurrence of cancer, whereas another emphasized various expressions of patient needs. One study explained how strategy and ability to adapt are not related to the type, the cause, nor the physical condition, but are mainly influenced by the age and the subjective experience of the patients. A last study showed that depression did not affect survival rate after surgery. Our systematic review found only few studies regarding the psychological condition after pancreatectomy and highlights the need to describe and characterize the patients' psychological characteristics in this setting.

From the *Aix-Marseille University, LPCPP, Aix-en-Provence;

Aix-Marseille University, INSERM, IRD, SESSTIM;

Department of Onco-Hematology, Institut Paoli-Calmettes; and

§Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.

Received for publication March 19, 2018; accepted February 18, 2019.

Address correspondence to: Léna Lounis, MA, 15 rue des 3 Frères Barthélémy, 13006 Marseille, France (e-mail:

The authors declare no conflict of interest.

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