ReviewSecretin-Stimulated Magnetic Resonance Imaging Assessment of the Benign Pancreatic Disorders Systematic Review and Proposal for a Standardized ProtocolMadzak, Adnan MD; Olesen, Søren Schou MD, PhD; Wathle, Gaute Kjellevold MD; Haldorsen, Ingfrid Salvesen MD, PhD; Drewes, Asbjørn Mohr MD, PhD, DMSc; Frøkjær, Jens Brøndum MD, PhDAuthor Information From the Departments of *Radiology and †Gastroenterology & Hepatology, Mech-Sense, Aalborg University Hospital, Aalborg, Denmark; ‡Department of Radiology, Haukeland University Hospital; and §Section for Radiology, Department of Clinical Medicine, University of Bergen, Bergen, Norway; and ∥Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Received for publication June 15, 2015; accepted December 1, 2015. Address correspondence to: Jens Brøndum Frøkjær, MD, PhD, Department of Radiology, Mech-Sense, Aalborg University Hospital, PO Box 365, DK-9100 Aalborg, Denmark (e-mail: [email protected]). The authors declare no conflict of interest. Pancreas: September 2016 - Volume 45 - Issue 8 - p 1092-1103 doi: 10.1097/MPA.0000000000000606 Buy Metrics Abstract This systemic review summarizes the current literature and general consensus on secretin-stimulated magnetic resonance imaging (s-MRI) of the benign pancreatic disorders and discusses important aspects on how s-MRI is optimally performed. The aim is to provide an overview, for clinicians and radiologist, of the s-MRI protocols and the range of clinical applications. Furthermore, the review will summarize the criteria for evaluation of pancreatic morphology and function based on s-MRI. The literature search indentified 69 original articles and 15 reviews. Chronic pancreatitis was the disease that was most frequently assessed by s-MRI (33%), followed by acute pancreatitis (9%). Dynamic thick-slab 2-dimensional magnetic resonance cholangiopancreatography was the most used imaging sequence (86%). The diameter of the main pancreatic duct (75%) and pancreatic exocrine function based on visual grading of duodenal filling (67%) were the most evaluated pancreatic features. Sufficient similarities between studies were identified to propose the most agreeable standardized s-MRI protocol for morphological and functional assessment of the pancreas. In the future, more research and increased collaboration between centers is necessary to achieve more consensus and optimization of s-MRI protocols. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.