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Acute Pancreatitis: Landmark Studies, Management Decisions, and the Future

Banks, Peter A. MD

doi: 10.1097/MPA.0000000000000632

A great deal of progress has been made in the last 50 years in the diagnosis and treatment of acute pancreatitis. Many landmark studies have been published and have focused on the classification of acute pancreatitis, markers of severity, important roles of imaging and endoscopy, and improvements in our treatment. This report will review several landmark studies, describe ongoing controversies in management decisions including standards of early fluid resuscitation and appropriate use of enteral feeding, and outline what will be required in the future to improve the care of patients with acute pancreatitis.

From the Center for Pancreatic Disease, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, MA.

Received for publication October 8, 2015; accepted February 20, 2016.

Reprints: Peter A. Banks, MD, Center for Pancreatic Disease, Brigham and Women's Hospital, 45 Francis St, Boston, MA 02115 (e-mail:

This author declares no conflict of interest.

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