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May 2020 - Volume 161 - Issue 5
pp: 877-1125




Trigeminal neuralgia associated with a solitary pontine lesion: clinical and neuroimaging definition of a new syndrome

Tohyama, Sarasa; Hung, Peter Shih-Ping; Cheng, Joshua C.; More

PAIN. 161(5):916-925, May 2020.

Exploring the neural correlates of touch and pain in women with provoked vestibulodynia

Sutton, Katherine S.; Yessick, Lindsey R.; Wild, Conor J.; More

PAIN. 161(5):926-937, May 2020.

Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor

Zorina-Lichtenwalter, Katerina; Maixner, William; Diatchenko, Luda

PAIN. 161(5):938-948, May 2020.

Recovery from nerve injury induced behavioral hypersensitivity in rats parallels resolution of abnormal primary sensory afferent signaling

Boada, M. Danilo; Martin, Thomas J.; Parker, Renee; More

PAIN. 161(5):949-959, May 2020.

Nociceptive input after peripheral nerve injury results in cognitive impairment and alterations in primary afferent physiology in rats

Boada, M. Danilo; Ririe, Douglas G.; Martin, Conner W.; More

PAIN. 161(5):960-969, May 2020.

A qualitative study of the experience and impact of neuropathic pain in people living with HIV

Scott, Whitney; Garcia Calderon Mendoza del Solar, Maite; Kemp, Harriet; More

PAIN. 161(5):970-978, May 2020.

Impact of opioid dose escalation on pain intensity: a retrospective cohort study

Hayes, Corey J.; Krebs, Erin E.; Hudson, Teresa; More

PAIN. 161(5):979-988, May 2020.

Epigenetic upregulation of acid-sensing ion channel 1 contributes to gastric hypersensitivity in adult offspring rats with prenatal maternal stress

Wang, Hong-Jun; Xu, Xue; Zhang, Ping-An; More

PAIN. 161(5):989-1004, May 2020.

Shared liability to pain, common mental disorders, and long-term work disability differs among women and men

Narusyte, Jurgita; Ropponen, Annina; Mittendorfer-Rutz, Ellenor; More

PAIN. 161(5):1005-1011, May 2020.

Informal caring for back pain: overlooked costs of back pain and projections to 2030

Schofield, Deborah; Zeppel, Melanie J.B.; Tanton, Robert; More

PAIN. 161(5):1012-1018, May 2020.

Celecoxib reduces cortical spreading depression–induced macrophage activation and dilatation of dural but not pial arteries in rodents: implications for mechanism of action in terminating migraine attacks

Schain, Aaron J.; Melo-Carrillo, Agustin; Ashina, Sait; More

PAIN. 161(5):1019-1026, May 2020.

Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study

Brenner, Darren M.; Argoff, Charles E.; Fox, Susan M.; More

PAIN. 161(5):1027-1036, May 2020.

Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood–brain barrier

Melo-Carrillo, Agustin; Schain, Aaron J.; Stratton, Jennifer; More

PAIN. 161(5):1037-1043, May 2020.

Sociodemographic patterns of pain in an urban community sample: an examination of intersectional effects of sex, race, age, and poverty status

Quiton, Raimi L.; Leibel, Daniel K.; Boyd, Eryka L.; More

PAIN. 161(5):1044-1051, May 2020.

Mechanistic pain profiling in young adolescents with patellofemoral pain before and after treatment: a prospective cohort study

Holden, Sinéad; Rathleff, Michael Skovdal; Thorborg, Kristian; More

PAIN. 161(5):1065-1071, May 2020.

A “dyadic dance”: pain catastrophizing moderates the daily relationships between parent mood and protective responses and child chronic pain

Neville, Alexandra; Griep, Yannick; Palermo, Tonya M.; More

PAIN. 161(5):1072-1082, May 2020.

Prescription of analgesics to long-term survivors of cancer in early adulthood, adolescence, and childhood in Norway: a national cohort study

Fredheim, Olav Magnus; Skurtveit, Svetlana; Loge, Jon Håvard; More

PAIN. 161(5):1083-1091, May 2020.

Lasmiditan inhibits calcitonin gene-related peptide release in the rodent trigeminovascular system

Labastida-Ramírez, Alejandro; Rubio-Beltrán, Eloísa; Haanes, Kristian A.; More

PAIN. 161(5):1092-1099, May 2020.

An unbiased and efficient assessment of excitability of sensory neurons for analgesic drug discovery

Mohammed, Zainab A.; Kaloyanova, Katerina; Nassar, Mohammed A.

PAIN. 161(5):1100-1108, May 2020.

c-Jun/p38MAPK/ASIC3 pathways specifically activated by nerve growth factor through TrkA are crucial for mechanical allodynia development

Chaumette, Tanguy; Delay, Lauriane; Barbier, Julie; More

PAIN. 161(5):1109-1123, May 2020.



Creator: Kenneth Childres, Senior Video Producer, University of Arkansas for Medical Sciences (UAMS)
Duration: 4:54
Drs. Corey Hayes and Bradley Martin present the findings of their study which examined the influence of escalating opioid doses on pain intensity among a cohort of Veterans with chronic pain. This observational study compared over 19,000 chronic opioid users that increased their opioid dose by at least 20% to an equivalent number of propensity matched persons who maintained their opioid doses and found that opioid dose escalation was not associated with improvements in NRS pain scores. These findings suggest that when contemplating whether to escalate opioid doses, the decision making process should center less on the potential benefit to improve pain intensity and more on the balance of other potential benefits and harms
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