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April 2020 - Volume 161 - Issue 4
pp: 663-876

New procedure of high-frequency repetitive transcranial magnetic stimulation for central neuropathic pain: a placebo-controlled randomized crossover study

Quesada, Charles; Pommier, Benjamin; Fauchon, Camille; More

PAIN. 161(4):718-728, April 2020.

Hub disruption in patients with chronic neck pain: a graph analytical approach

De Pauw, Robby; Aerts, Hannelore; Siugzdaite, Roma; More

PAIN. 161(4):729-741, April 2020.

Personal, biomechanical, psychosocial, and organizational risk factors for carpal tunnel syndrome: a structural equation modeling approach

Roquelaure, Yves; Garlantézec, Ronan; Evanoff, Bradley A.; More

PAIN. 161(4):749-757, April 2020.

Nicotinamide adenine dinucleotide phosphate oxidase 2–derived reactive oxygen species contribute to long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn and persistent mirror-image pain following high-frequency stimulus of the sciatic nerve

Xu, Jing; Wei, Xuxia; Gao, Feng; More

PAIN. 161(4):758-772, April 2020.

Functional and anatomical deficits in visceral nociception with age: a mechanism of silent appendicitis in the elderly?

Cibert-Goton, Vincent; Kung, Victor W.S.; McGuire, Cian; More

PAIN. 161(4):773-786, April 2020.

Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study

Heitmann, Henrik; Haller, Bernhard; Tiemann, Laura; More

PAIN. 161(4):787-796, April 2020.

Complex regional pain syndrome patient immunoglobulin M has pronociceptive effects in the skin and spinal cord of tibia fracture mice

Guo, Tian-Zhi; Wei, Tzuping; Tajerian, Maral; More

PAIN. 161(4):797-809, April 2020.

Ethnic disparities in pain processing among healthy adults: μ-opioid receptor binding potential as a putative mechanism

Letzen, Janelle E.; Mun, Chung Jung; Kuwabara, Hiroto; More

PAIN. 161(4):810-820, April 2020.

Sleep disturbance underlies the co-occurrence of trauma and pediatric chronic pain: a longitudinal examination

Pavlova, Maria; Kopala-Sibley, Daniel C.; Nania, Cara; More

PAIN. 161(4):821-830, April 2020.

Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models

Urru, Matteo; Muzzi, Mirko; Coppi, Elisabetta; More

PAIN. 161(4):831-841, April 2020.

Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents

Tiwari, Vinod; He, Shao-Qiu; Huang, Qian; More

PAIN. 161(4):842-855, April 2020.

Temporal instability of salience network activity in migraine with aura

Veréb, Dániel; Szabó, Nikoletta; Tuka, Bernadett; More

PAIN. 161(4):856-864, April 2020.

Marked sexual dimorphism in neuroendocrine mechanisms for the exacerbation of paclitaxel-induced painful peripheral neuropathy by stress

Ferrari, Luiz F.; Araldi, Dioneia; Green, Paul G.; More

PAIN. 161(4):865-874, April 2020.

Reply to Boland and Bennett

Novy, Diane M.; Nelson, David V.; Koyyalagunta, Dhanalakshmi; More

PAIN. 161(4):875-876, April 2020.

Creator: Carole Federico and Jonathan Kimmelman
Duration: 4:17
Video abstract for the meta-research paper “The systematic review and meta-analysis of pregabalin preclinical studies,” authored by Carole A. Federico (McGill University), Jeffrey S. Mogil, Tim Ramsay, Dean Fergusson and Jonathan Kimmelman. Describes a research study exploring the quality and design characteristics of 531 behavioral pain studies and tests the relationship between design features and effect sizes. Pregabalin is approved by the FDA to treat a number of pain conditions, including diabetic peripheral neuropathy, postherpetic neuralgia, neuropathic pain associated with spinal cord injury and fibromyalgia. Internal validity, construct validity, external validity, publication bias and dose-response were assessed.
Creator: Janelle Letzen, PhD and Claudia Campbell, PhD
Duration: 5:34
Although ethnic differences in pain perception are well documented, the underlying mechanisms for these outcomes has not been established. The present study sought to address this knowledge gap by examining differences in µ-selective agonist binding potential (BPND; [11C]-Carfentanil) between 27 non-Hispanic Black (NHB) and 27 demographically-similar, non-Hispanic White (NHW) participants. Results suggest that NHB individuals might have generally greater unoccupied MOR density than NHW peers. Findings have implications for physiological differences underlying ethnicity-related pain disparities.