Refractory dependence on opioid analgesics Ballantyne, Jane C.; Sullivan, Mark D.; Koob, George F. Ballantyne, Jane C.; Sullivan, Mark D.; Koob, George F. Less PAIN. 160(12):2655-2660, December 2019. Favorite PDF Permissions Buy SDC
Itch sensitization? A systematic review of studies using quantitative sensory testing in patients with chronic itch van Laarhoven, Antoinette I.M.; Marker, Jens B.; Elberling, Jesper; More van Laarhoven, Antoinette I.M.; Marker, Jens B.; Elberling, Jesper; Yosipovitch, Gil; Arendt-Nielsen, Lars; Andersen, Hjalte H. Less PAIN. 160(12):2661-2678, December 2019. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Free SDC
Conditioned pain modulation as a biomarker of chronic pain: a systematic review of its concurrent validity Fernandes, Carina; Pidal-Miranda, Marina; Samartin-Veiga, Noelia; More Fernandes, Carina; Pidal-Miranda, Marina; Samartin-Veiga, Noelia; Carrillo-de-la-Peña, María T. Less PAIN. 160(12):2679-2690, December 2019. Abstract Abstract Favorite PDF Permissions Buy SDC
A randomized pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling during surgery Wodehouse, Theresa; Demopoulos, Mary; Petty, Robert; More Wodehouse, Theresa; Demopoulos, Mary; Petty, Robert; Miraki-Moud, Farideh; Belhaj, Alla; Husband, Michael; Fulton, Laura; Randive, Nilesh; Oksche, Alexander; Mehta, Vivek; Gribben, John; Langford, Richard Less PAIN. 160(12):2691-2698, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pilot study evaluating the effects of morphine and oxycodone on immunosuppression pathways in noncancer surgery. Two-hour postincision morphine appears to be immunosuppressive compared with oxycodone. Buy
Epidermal expression of human TRPM8, but not of TRPA1 ion channels, is associated with sensory responses to local skin cooling Weyer-Menkhoff, Iris; Pinter, Andreas; Schlierbach, Hannah; More Weyer-Menkhoff, Iris; Pinter, Andreas; Schlierbach, Hannah; Schänzer, Anne; Lötsch, Jörn Less PAIN. 160(12):2699-2709, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The distribution of TRPM8 but not TRPA1 expression in epidermal nerve fibers provides an explanation of the (bi)modal distribution of human cold pain thresholds. Buy SDC
Dermorphin [D-Arg2, Lys4] (1-4) amide inhibits below-level heat hypersensitivity in mice after contusive thoracic spinal cord injury Liu, Shuguang; Huang, Qian; He, Shaoqiu; More Liu, Shuguang; Huang, Qian; He, Shaoqiu; Chen, Zhiyong; Gao, Xinyan; Ma, Danxu; Duan, Wanru; Ford, Neil; Yang, Fei; Chen, Xueming; Raja, Srinivasa N.; Hao, Dingjun; Guan, Yun Less PAIN. 160(12):2710-2723, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: This study shows upregulations of mu-opioid receptor expression in the lumbar spinal cord and sciatic nerves after thoracic spinal cord injury and inhibition of heat hypersensitivity by DALDA in mice. Buy SDC
Fatty acid suppression of glial activation prevents central neuropathic pain after spinal cord injury Georgieva, Marieta; Wei, Yuting; Dumitrascuta, Maria; More Georgieva, Marieta; Wei, Yuting; Dumitrascuta, Maria; Pertwee, Roger; Finnerup, Nanna B.; Huang, Wenlong Less PAIN. 160(12):2724-2742, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Systemic treatments with docosahexaenoic acid prevent central pain development after spinal injury and partially abolish already established central pain at a chronic stage of injury. Buy SDC
Motor simulation is disturbed when experiencing pain Cracco, Emiel; Clauwaert, Amanda; Van den Broeck, Yentl; More Cracco, Emiel; Clauwaert, Amanda; Van den Broeck, Yentl; Van Damme, Stefaan; Brass, Marcel Less PAIN. 160(12):2743-2750, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pain disturbs motor simulation, as measured by automatic imitation, both when pain is linked to movement execution and when it is not. Buy
Brain dysfunction in chronic pain patients assessed by resting-state electroencephalography Ta Dinh, Son; Nickel, Moritz M.; Tiemann, Laura; More Ta Dinh, Son; Nickel, Moritz M.; Tiemann, Laura; May, Elisabeth S.; Heitmann, Henrik; Hohn, Vanessa D.; Edenharter, Günther; Utpadel-Fischler, Daniel; Tölle, Thomas R.; Sauseng, Paul; Gross, Joachim; Ploner, Markus Less PAIN. 160(12):2751-2765, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Resting-state electroencephalography reveals increased synchrony at theta and gamma frequencies in frontal brain areas and global network reorganization at gamma frequencies in chronic pain patients. Buy
Heme and sensory neuropathy: insights from novel mutations in the heme exporter feline leukemia virus subgroup C receptor 1 Bertino, Francesca; Firestone, Kyra; Bellacchio, Emanuele; More Bertino, Francesca; Firestone, Kyra; Bellacchio, Emanuele; Jackson, Kelly E.; Asamoah, Alexander; Hersh, Joseph; Fiorito, Veronica; Destefanis, Francesca; Gonser, Rusty; Tucker, Megan E.; Altruda, Fiorella; Tolosano, Emanuela; Chiabrando, Deborah Less PAIN. 160(12):2766-2775, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Mutations in the translational initiator codon of the heme exporter FLVCR1 cause hereditary sensory and autonomic neuropathy. Buy SDC
Dynamic functional connectivity of the migraine brain: a resting-state functional magnetic resonance imaging study Lee, Mi Ji; Park, Bo-Yong; Cho, Soohyun; More Lee, Mi Ji; Park, Bo-Yong; Cho, Soohyun; Park, Hyunjin; Kim, Sung-Tae; Chung, Chin-Sang Less PAIN. 160(12):2776-2786, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Dynamic connectivity analysis of the resting-state functional magnetic resonance imaging provides better knowledge of brain networks involved in migraine pathophysiology. Buy SDC
Essential key messages about diagnosis, imaging, and self-care for people with low back pain: a modified Delphi study of consumer and expert opinions French, Simon D.; Nielsen, Mandy; Hall, Leanne; More French, Simon D.; Nielsen, Mandy; Hall, Leanne; Nicolson, Philippa J.A.; van Tulder, Maurits; Bennell, Kim L.; Hinman, Rana S.; Maher, Chris G.; Jull, Gwendolen; Hodges, Paul W. Less PAIN. 160(12):2787-2797, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: This list of key messages about diagnosis, imaging, and self-care for people with low back pain, presented in plain language, was developed by experts and consumers. Buy SDC
A potential role for T-type calcium channels in homocysteinemia-induced peripheral neuropathy Gaifullina, Aisylu S.; Lazniewska, Joanna; Gerasimova, Elena V.; More Gaifullina, Aisylu S.; Lazniewska, Joanna; Gerasimova, Elena V.; Burkhanova, Gulshat F.; Rzhepetskyy, Yuriy; Tomin, Andriy; Rivas-Ramirez, Paula; Huang, Junting; Cmarko, Leos; Zamponi, Gerald W.; Sitdikova, Guzel F.; Weiss, Norbert Less PAIN. 160(12):2798-2810, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Homocysteine modulates T-type calcium channel expression through a protein kinase C–dependent signaling pathway and possibly contributes to homocysteinemia-induced mechanical allodynia. Buy SDC
Perceptual and motor responses directly and indirectly mediate the effects of noxious stimuli on autonomic responses Tiemann, Laura; Hohn, Vanessa D.; Ta Dinh, Son; More Tiemann, Laura; Hohn, Vanessa D.; Ta Dinh, Son; May, Elisabeth S.; Nickel, Moritz M.; Heitmann, Henrik; Ploner, Markus Less PAIN. 160(12):2811-2818, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Motor and perceptual processes shape autonomic responses to noxious stimuli, which likely serves the integration of contextual processes into flexible and adaptive responses to threat. Buy
Withdrawal from an opioid induces a transferable memory trace in the cerebrospinal fluid Drdla-Schutting, Ruth; Heinl, Céline; Hadschieff, Viktoria; More Drdla-Schutting, Ruth; Heinl, Céline; Hadschieff, Viktoria; Sandkühler, Jürgen Less PAIN. 160(12):2819-2828, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Withdrawal from an opioid induces synaptic plasticity in pain pathways, which is transferable through the cerebrospinal fluid between animals. Buy
Whole-brain functional network disruption in chronic pain with disk herniation Huang, Shishi; Wakaizumi, Kenta; Wu, Binbin; More Huang, Shishi; Wakaizumi, Kenta; Wu, Binbin; Shen, Bangli; Wu, Bo; Fan, Linyu; Baliki, Marwan N.; Zhan, Gonghao; Apkarian, A. Vania; Huang, Lejian Less PAIN. 160(12):2829-2840, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Brain functional network properties were globally disrupted in lumbar disk herniation patients with chronic pain. The relationship between pain and graph disruption indices was limited to males with high education. Buy
Daily and bidirectional linkages between pain catastrophizing and spouse responses Martire, Lynn M.; Zhaoyang, Ruixue; Marini, Christina M.; More Martire, Lynn M.; Zhaoyang, Ruixue; Marini, Christina M.; Nah, Suyoung; Darnall, Beth D. Less PAIN. 160(12):2841-2847, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Lagged effects across days provided evidence of a cyclical process whereby catastrophizing leads to punishing responses from the spouse, which in turn contribute to greater catastrophizing. Buy
Paracetamol is ineffective for acute low back pain even for patients who comply with treatment: complier average causal effect analysis of a randomized controlled trial Schreijenberg, Marco; Lin, Chung-Wei Christine; Mclachlan, Andrew J.; More Schreijenberg, Marco; Lin, Chung-Wei Christine; Mclachlan, Andrew J.; Williams, Christopher M.; Kamper, Steven J.; Koes, Bart W.; Maher, Christopher G.; Billot, Laurent Less PAIN. 160(12):2848-2854, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Paracetamol is not more effective than placebo for acute low back pain in patients who comply with the treatment regimen. Buy SDC
Autoantibodies produce pain in complex regional pain syndrome by sensitizing nociceptors Cuhadar, Ulku; Gentry, Clive; Vastani, Nisha; More Cuhadar, Ulku; Gentry, Clive; Vastani, Nisha; Sensi, Serena; Bevan, Stuart; Goebel, Andreas; Andersson, David A. Less PAIN. 160(12):2855-2865, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Passive transfer of complex regional pain syndrome patient IgG to mice produces persistent regional postoperative pain by sensitizing nociceptors. Buy
Recurrent low back pain patients demonstrate facilitated pronociceptive mechanisms when in pain, and impaired antinociceptive mechanisms with and without pain McPhee, Megan E.; Graven-Nielsen, Thomas McPhee, Megan E.; Graven-Nielsen, Thomas Less PAIN. 160(12):2866-2876, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Widespread pressure hyperalgesia and facilitated pronociception in low back pain patients were only present during a painful episode, whereas antinociception remained impaired in pain-free periods. Buy SDC
Cell-specific role of histone deacetylase 6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers Ma, Jiacheng; Trinh, Ronnie T.; Mahant, Iteeben D.; More Ma, Jiacheng; Trinh, Ronnie T.; Mahant, Iteeben D.; Peng, Bo; Matthias, Patrick; Heijnen, Cobi J.; Kavelaars, Annemieke Less PAIN. 160(12):2877-2890, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Sensory neuron HDAC6 is key mediator for cisplatin-induced loss of intraepidermal nerve fibers, whereas successful prevention of mechanical allodynia involves T cells as well. Buy
Effects of open-label placebo on pain, functional disability, and spine mobility in patients with chronic back pain: a randomized controlled trial Kleine-Borgmann, Julian; Schmidt, Katharina; Hellmann, Andreas; More Kleine-Borgmann, Julian; Schmidt, Katharina; Hellmann, Andreas; Bingel, Ulrike Less PAIN. 160(12):2891-2897, December 2019. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: This study demonstrates that open-label placebo treatments are safe, well tolerated and reduce pain, disability, and depressive symptoms in patients with chronic back pain. Buy SDC
Anti-inflammatory drugs with more penetration into the central nervous system may contribute to the treatment of trigeminal neuralgia Sun, Liang; Liang, Hansheng; Feng, Yi Sun, Liang; Liang, Hansheng; Feng, Yi Less PAIN. 160(12):2898, December 2019. Favorite PDF Permissions Buy
Reply to Sun et al. Ericson, Hans; Hamdeh, Sami Abu; Freyhult, Eva; More Ericson, Hans; Hamdeh, Sami Abu; Freyhult, Eva; Stiger, Fredrik; Bäckryd, Emmanuel; Svenningsson, Anders; Gordh, Torsten; Kultima, Kim Less PAIN. 160(12):2898-2899, December 2019. Favorite PDF Permissions Buy
