Responses to the sham treatment vs expectancy effects Colloca, Luana Colloca, Luana Less PAIN. 159(10):1905, October 2018. Favorite PDF Permissions Buy
Systematic reviews with meta-analysis on cannabis-based medicines for chronic pain: a methodological and political minefield Häuser, Winfried; Finnerup, Nanna B.; Moore, R. Andrew Häuser, Winfried; Finnerup, Nanna B.; Moore, R. Andrew Less PAIN. 159(10):1906-1907, October 2018. Favorite PDF Permissions Buy
Targeting toll-like receptor-4 (TLR4)—an emerging therapeutic target for persistent pain states Bruno, Kelly; Woller, Sarah A.; Miller, Yury I.; More Bruno, Kelly; Woller, Sarah A.; Miller, Yury I.; Yaksh, Tony L.; Wallace, Mark; Beaton, Graham; Chakravarthy, Krishnan Less PAIN. 159(10):1908-1915, October 2018. Abstract Abstract Favorite PDF Permissions Buy
Chronic pain in survivors of childhood cancer: a developmental model of pain across the cancer trajectory Alberts, Nicole M.; Gagnon, Michelle M.; Stinson, Jennifer N. Alberts, Nicole M.; Gagnon, Michelle M.; Stinson, Jennifer N. Less PAIN. 159(10):1916-1927, October 2018. Favorite PDF Permissions Buy SDC
Does the word “placebo” evoke a placebo response? Bennett, Gary J. Bennett, Gary J. Less PAIN. 159(10):1928-1931, October 2018. Favorite PDF Permissions Buy
Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies Stockings, Emily; Campbell, Gabrielle; Hall, Wayne D.; More Stockings, Emily; Campbell, Gabrielle; Hall, Wayne D.; Nielsen, Suzanne; Zagic, Dino; Rahman, Rakin; Murnion, Bridin; Farrell, Michael; Weier, Megan; Degenhardt, Louisa Less PAIN. 159(10):1932-1954, October 2018. Abstract Abstract Favorite PDF Permissions Buy SDC
Should thoracic paravertebral blocks be used to prevent chronic postsurgical pain after breast cancer surgery? A systematic analysis of evidence in light of IMMPACT recommendations Hussain, Nasir; Shastri, Uma; McCartney, Colin J.L.; More Hussain, Nasir; Shastri, Uma; McCartney, Colin J.L.; Gilron, Ian; Fillingim, Roger B.; Clarke, Hance; Katz, Joel; Juni, Peter; Laupacis, Andreas; Wijeysundera, Duminda; Abdallah, Faraj W. Less PAIN. 159(10):1955-1971, October 2018. Abstract Abstract Favorite PDF Permissions Buy SDC
Pressure-induced referred pain areas are more expansive in individuals with a recovered fracture Doménech-García, Víctor; Skuli Palsson, Thorvaldur; Boudreau, Shellie Ann; More Doménech-García, Víctor; Skuli Palsson, Thorvaldur; Boudreau, Shellie Ann; Herrero, Pablo; Graven-Nielsen, Thomas Less PAIN. 159(10):1972-1979, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pain-free individuals with a recovered fracture showed a heightened response after pressure-induced referred pain when the pain system was sensitized through delayed onset muscular soreness. Buy
Trigeminal ganglion transcriptome analysis in 2 rat models of medication-overuse headache reveals coherent and widespread induction of pronociceptive gene expression patterns Buonvicino, Daniela; Urru, Matteo; Muzzi, Mirko; More Buonvicino, Daniela; Urru, Matteo; Muzzi, Mirko; Ranieri, Giuseppe; Luceri, Cristina; Oteri, Claudia; Lapucci, Andrea; Chiarugi, Alberto Less PAIN. 159(10):1980-1988, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Chronic rat exposure to eletriptan or indomethacin prompts similar induction of pronociceptive genes within the trigeminal ganglion, a condition explaining pathogenesis of medication-overuse headache. Buy
Psychophysical and vasomotor evidence for interdependency of TRPA1 and TRPV1-evoked nociceptive responses in human skin: an experimental study Nielsen, Thomas Arendt; Eriksen, Matilde Alida; Gazerani, Parisa; More Nielsen, Thomas Arendt; Eriksen, Matilde Alida; Gazerani, Parisa; Andersen, Hjalte Holm Less PAIN. 159(10):1989-2001, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: TRPA1 and TRPV1 are crucial nociceptive transducers. Using capsaicin ablation in human skin we reveal that TRPA1-induced pain responses depend on intact capsaicin-sensitive fibers, signifying substantial functional TRPA1–TRPV1 overlap. Buy
Sensory sensitivity and symptom severity represent unique dimensions of chronic pain: a MAPP Research Network study Schrepf, Andrew; Williams, David A.; Gallop, Robert; More Schrepf, Andrew; Williams, David A.; Gallop, Robert; Naliboff, Bruce D.; Basu, Neil; Kaplan, Chelsea; Harper, Daniel E.; Landis, J. Richard; Clemens, J. Quentin; Strachan, Eric; Griffith, James W.; Afari, Niloofar; Hassett, Afton; Pontari, Michel A.; Clauw, Daniel J.; Harte, Steven E.; for the MAPP Research Network Less PAIN. 159(10):2002-2011, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The symptomology of what has been called centralized pain can be described as 2 clusters, each related to different aspects of the clinical pain experience. Buy SDC
Pain processing in the human brainstem and spinal cord before, during, and after the application of noxious heat stimuli Stroman, Patrick W.; Ioachim, Gabriela; Powers, Jocelyn M.; More Stroman, Patrick W.; Ioachim, Gabriela; Powers, Jocelyn M.; Staud, Roland; Pukall, Caroline Less PAIN. 159(10):2012-2020, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Functional magnetic resonance imaging of the brainstem and spinal cord in 59 healthy participants indicates that autonomic regulation influences descending pain regulation and individual pain sensitivity. Buy SDC
Dermal nerve fibre and mast cell density, and proximity of mast cells to nerve fibres in the skin of patients with complex regional pain syndrome Morellini, Natalie; Finch, Philip M.; Goebel, Andreas; More Morellini, Natalie; Finch, Philip M.; Goebel, Andreas; Drummond, Peter D. Less PAIN. 159(10):2021-2029, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Loss of dermal nerve fibres in complex regional pain syndrome might disrupt neural–mast cell interactions, thereby delaying tissue repair and contributing to chronic inflammation. Buy SDC
Color-selective photophobia in ictal vs interictal migraineurs and in healthy controls Nir, Rony-Reuven; Lee, Alice J.; Huntington, Shaelah; More Nir, Rony-Reuven; Lee, Alice J.; Huntington, Shaelah; Noseda, Rodrigo; Bernstein, Carolyn A.; Fulton, Anne B.; Bertisch, Suzanne M.; Hovaguimian, Alexandra; Buettner, Catherine; Borsook, David; Burstein, Rami Less PAIN. 159(10):2030-2034, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Migraineurs prefer green light because it hurts them less than other colors during migraine and is less likely to trigger a headache in between attacks. Buy
Cultural influences on parental responses to children's pain Kristjansdottir, Olof; McGrath, Patrick J.; Finley, G. Allen; More Kristjansdottir, Olof; McGrath, Patrick J.; Finley, G. Allen; Kristjansdottir, Gudrun; Siripul, Pulsuk; Mackinnon, Sean P.; Yoshida, Yoko Less PAIN. 159(10):2035-2049, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Culture influences pain-related parental behaviors, but not always as expected. Solicitous pain-related parental behavior seems to be a universal response to children in pain. Buy SDC
Racial differences in opioid prescribing for children in the United States Groenewald, Cornelius B.; Rabbitts, Jennifer A.; Hansen, Elizabeth E.; More Groenewald, Cornelius B.; Rabbitts, Jennifer A.; Hansen, Elizabeth E.; Palermo, Tonya M. Less PAIN. 159(10):2050-2057, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Race and ethnic differences exist in opioid prescribing for children in the United States. Health care providers' race and ethnicity may drive extant opioid differences. Buy
Dynamic sodium imaging at ultra-high field reveals progression in a preclinical migraine model Abad, Nastaren; Rosenberg, Jens T.; Hike, David C.; More Abad, Nastaren; Rosenberg, Jens T.; Hike, David C.; Harrington, Michael G.; Grant, Samuel C. Less PAIN. 159(10):2058-2065, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Longitudinal 23Na magnetic resonance imaging maps the evolution of acute migraine after nitroglycerine administration reporting significant, sustained increases in brainstem and cerebrospinal fluid sodium before established behavioral metrics. Buy SDC
Mixed-methods development of a new patient-reported outcome instrument for chronic low back pain: part 2—The Patient Assessment for Low Back Pain–Impacts (PAL-I) Bushnell, Donald M.; Blum, Steven I.; Liedgens, Hiltrud; More Bushnell, Donald M.; Blum, Steven I.; Liedgens, Hiltrud; Martin, Mona L.; Freynhagen, Rainer; Wallace, Mark; Argoff, Charles; Eerdekens, Mari?lle; Kok, Maurits; Patrick, Donald L. Less PAIN. 159(10):2066-2075, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: The Patient Assessment for Low Back Pain–Impacts is a newly developed patient-reported outcome instrument to assess specific impacts of chronic low back pain for use in clinical trials and practice. Go to Full Text of this Article Open
Multivariate pattern classification of brain white matter connectivity predicts classic trigeminal neuralgia Zhong, Jidan; Chen, David Qixiang; Hung, Peter Shih-Ping; More Zhong, Jidan; Chen, David Qixiang; Hung, Peter Shih-Ping; Hayes, Dave J.; Liang, Kevin E.; Davis, Karen D.; Hodaie, Mojgan Less PAIN. 159(10):2076-2087, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A white matter connectivity pattern involving areas implicated in the sensory, affective, and cognitive dimensions of pain predicts trigeminal neuralgia with an 88% accuracy. Buy SDC
Patterns of recovery from pain after cesarean delivery Booth, Jessica L.; Sharpe, Emily E.; Houle, Timothy T.; More Booth, Jessica L.; Sharpe, Emily E.; Houle, Timothy T.; Harris, Lynnette; Curry, Regina S.; Aschenbrenner, Carol A.; Eisenach, James C. Less PAIN. 159(10):2088-2096, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Daily pain intensity after cesarean delivery declines in a log(time) manner followed by a change at 2 to 4 weeks to a linear or quadratic form. Buy
Changes in pain intensity after discontinuation of long-term opioid therapy for chronic noncancer pain McPherson, Sterling; Lederhos Smith, Crystal; Dobscha, Steven K.; More McPherson, Sterling; Lederhos Smith, Crystal; Dobscha, Steven K.; Morasco, Benjamin J.; Demidenko, Michael I.; Meath, Thomas H.A.; Lovejoy, Travis I. Less PAIN. 159(10):2097-2104, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pain intensity as assessed by numeric rating scale pain intensity scores did not significantly change in the 12 months after discontinuation of long-term opioid therapy. Buy SDC
Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist Iadarola, Michael J.; Sapio, Matthew R.; Raithel, Stephen J.; More Iadarola, Michael J.; Sapio, Matthew R.; Raithel, Stephen J.; Mannes, Andrew J.; Brown, Dorothy Cimino Less PAIN. 159(10):2105-2114, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: We investigate nonopioid peripheral analgesia using intra-articular resiniferatoxin in canine subjects with naturally occurring osteoarthritis and present the corresponding transcriptional fingerprint of the dog dorsal root ganglion to enable informed translational studies. Buy SDC
Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain François-Moutal, Liberty; Dustrude, Erik T.; Wang, Yue; More François-Moutal, Liberty; Dustrude, Erik T.; Wang, Yue; Brustovetsky, Tatiana; Dorame, Angie; Ju, Weina; Moutal, Aubin; Perez-Miller, Samantha; Brustovetsky, Nickolay; Gokhale, Vijay; Khanna, May; Khanna, Rajesh Less PAIN. 159(10):2115-2127, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Targeting CRMP2 SUMOylation by disrupting the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction is a promising therapeutic strategy for chronic pain. Buy
What do clinicians consider when assessing chronic low back pain? A content analysis of multidisciplinary pain centre team assessments of functioning, disability, and health Bagraith, Karl S.; Strong, Jenny; Meredith, Pamela J.; More Bagraith, Karl S.; Strong, Jenny; Meredith, Pamela J.; McPhail, Steven M. Less PAIN. 159(10):2128-2136, October 2018. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A qualitative examination of multidisciplinary pain centre clinical assessments revealed novel insights into the content of team assessments of chronic low back pain that can be used to improve health care delivery. Buy SDC