Taking adolescent prescription opioid use in context: risk stratification in early mid-life based on medical and nonmedical use Hah, Jennifer Hah, Jennifer Less PAIN. 157(10):2143-2144, October 2016. Favorite PDF Permissions Buy
More than “just do it”—fear-based exposure for complex regional pain syndrome Moseley, G. Lorimer Moseley, G. Lorimer Less PAIN. 157(10):2145-2147, October 2016. Favorite PDF Permissions Buy
What the brain tells the spinal cord Bannister, Kirsty; Dickenson, Anthony H. Bannister, Kirsty; Dickenson, Anthony H. Less PAIN. 157(10):2148-2151, October 2016. Favorite PDF Permissions Open
Smell of pain: intersection of nociception and olfaction Lötsch, Jörn; Hähner, Antje; Gossrau, Gudrun; More Lötsch, Jörn; Hähner, Antje; Gossrau, Gudrun; Hummel, Cornelia; Walter, Carmen; Ultsch, Alfred; Hummel, Thomas Less PAIN. 157(10):2152-2157, October 2016. Favorite PDF Permissions Buy SDC
The epidemiology of chronic pain Macfarlane, Gary J. Macfarlane, Gary J. Less PAIN. 157(10):2158-2159, October 2016. Favorite PDF Permissions Free
Back schools for the treatment of chronic low back pain: possibility of benefit but no convincing evidence after 47 years of research—systematic review and meta-analysis Straube, Sebastian; Harden, Markus; Schröder, Heiko; More Straube, Sebastian; Harden, Markus; Schröder, Heiko; Arendacka, Barbora; Fan, Xiangning; Moore, R. Andrew; Friede, Tim Less PAIN. 157(10):2160-2172, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: A systematic review demonstrates that the evidence base for the use of back schools to treat low back pain is weak. No unequivocal evidence of benefit has emerged; adverse events were poorly reported in the studies. Go to Full Text of this Article Open
Adolescent context of exposure to prescription opioids and substance use disorder symptoms at age 35: a national longitudinal study McCabe, Sean Esteban; Veliz, Philip; Schulenberg, John E. McCabe, Sean Esteban; Veliz, Philip; Schulenberg, John E. Less PAIN. 157(10):2173-2178, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Appropriate medical use of prescription opioids in adolescence was not associated with substance use disorder symptoms in adulthood, whereas any nonmedical use predicted substance use disorder symptoms. Buy SDC
The effect of pain on task switching: pain reduces accuracy and increases reaction times across multiple switching paradigms Attridge, Nina; Keogh, Edmund; Eccleston, Christopher Attridge, Nina; Keogh, Edmund; Eccleston, Christopher Less PAIN. 157(10):2179-2193, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Participants completed attention switching tasks with or without pain. Pain increased reaction times on multiple task versions but did not increase switch costs. Buy SDC
Insular balance of glutamatergic and GABAergic signaling modulates pain processing Watson, Christopher J. Watson, Christopher J. Less PAIN. 157(10):2194-2207, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Decreasing the insular excitatory to inhibitory signaling ratio in nerve-injured rats reduces persistent pain-like behaviors. Increasing this ratio in uninjured rats increases pain-like behaviors. Buy
Does association of opioid use with pain and function differ by fibromyalgia or widespread pain status? Turner, Judith A.; Shortreed, Susan M.; Saunders, Kathleen W.; More Turner, Judith A.; Shortreed, Susan M.; Saunders, Kathleen W.; LeResche, Linda; Thielke, Stephen; Von Korff, Michael Less PAIN. 157(10):2208-2216, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Among patients who sustained long-term opioid use for chronic pain, pain and function outcomes did not differ for those with fibromyalgia. Buy SDC
Endogenous opioidergic dysregulation of pain in fibromyalgia: a PET and fMRI study Schrepf, Andrew; Harper, Daniel E.; Harte, Steven E.; More Schrepf, Andrew; Harper, Daniel E.; Harte, Steven E.; Wang, Heng; Ichesco, Eric; Hampson, Johnson P.; Zubieta, Jon-Kar; Clauw, Daniel J.; Harris, Richard E. Less PAIN. 157(10):2217-2225, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The μ-opioid receptor system is intricately linked to brain responses to pain in fibromyalgia. Patients with fibromyalgia may be less responsive to endogenous and other opioids. Buy SDC
Using a graphical risk tool to examine willingness to take migraine prophylactic medications Turner, Dana P.; Golding, Adrienne N.; Houle, Timothy T. Turner, Dana P.; Golding, Adrienne N.; Houle, Timothy T. Less PAIN. 157(10):2226-2234, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: When informed of the side effect profile using graphical risk communication tools, the majority of headache sufferers would not be willing to take migraine medications. Buy
A novel intrinsic analgesic mechanism: the enhancement of the conduction failure along polymodal nociceptive C-fibers Wang, Xiuchao; Wang, Shan; Wang, Wenting; More Wang, Xiuchao; Wang, Shan; Wang, Wenting; Duan, Jianhong; Zhang, Ming; Lv, Xiaohua; Niu, Chunxiao; Tan, Chao; Wu, Yuanbin; Yang, Jing; Hu, Sanjue; Xing, Junling Less PAIN. 157(10):2235-2247, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Conduction failure represents a prime target for modulating pain signals along C-fibers and might provide a new promising strategy to modulating pain with little side effects. Go to Full Text of this Article Open SDC
Combined glutamate and glutamine levels in pain-processing brain regions are associated with individual pain sensitivity Zunhammer, Matthias; Schweizer, Lauren M.; Witte, Vanessa; More Zunhammer, Matthias; Schweizer, Lauren M.; Witte, Vanessa; Harris, Richard E.; Bingel, Ulrike; Schmidt-Wilcke, Tobias Less PAIN. 157(10):2248-2256, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Levels of combined glutamate and glutamine, but not γ-aminobutyric acid within pain-related brain regions of healthy subjects are positively correlated with experimental pain sensitivity. Buy SDC
The Pain Course: exploring predictors of clinical response to an Internet-delivered pain management program Dear, B.F.; Gandy, M.; Karin, E.; More Dear, B.F.; Gandy, M.; Karin, E.; Ricciardi, T.; Langman, N.; Staples, L.G.; Fogliati, V.J.; Sharpe, L.; McLellan, L.F.; Titov, N. Less PAIN. 157(10):2257-2268, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: No dominant predictors of clinical response to an Internet-delivered pain management program were found. A broad range of participants may benefit from these programs. Buy
Health-related quality of life and burden of disease in chronic pain measured with the 15D instrument Vartiainen, Pekka; Heiskanen, Tarja; Sintonen, Harri; More Vartiainen, Pekka; Heiskanen, Tarja; Sintonen, Harri; Roine, Risto P.; Kalso, Eija Less PAIN. 157(10):2269-2276, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The health-related quality of life of chronic pain patients is one of the poorest recorded using the 15D instrument, which appears sensitive, discriminative and useful. Buy
Posttraumatic stress disorder symptoms in youth with vs without chronic pain Noel, Melanie; Wilson, Anna C.; Holley, Amy Lewandowski; More Noel, Melanie; Wilson, Anna C.; Holley, Amy Lewandowski; Durkin, Lindsay; Patton, Michaela; Palermo, Tonya M. Less PAIN. 157(10):2277-2284, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Youth with chronic pain and their parents had higher posttraumatic stress disorder symptoms than pain-free peers. Among youth with pain, posttraumatic stress disorder symptoms were linked to reduced functioning. Buy
Reduced thermal sensitivity and increased opioidergic tone in the TASTPM mouse model of Alzheimer's disease Aman, Yahyah; Pitcher, Thomas; Simeoli, Raffaele; More Aman, Yahyah; Pitcher, Thomas; Simeoli, Raffaele; Ballard, Clive; Malcangio, Marzia Less PAIN. 157(10):2285-2296, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Increased inhibition and decreased excitation in the spinal cord may be responsible for the reduced thermal sensitivity in TASTPM transgenic mouse model of Alzheimer disease. Go to Full Text of this Article Open
A standardized clinical evaluation of phenotypic diversity in diabetic polyneuropathy Scholz, Joachim; Rathmell, James P.; David, William S.; More Scholz, Joachim; Rathmell, James P.; David, William S.; Chad, David A.; Broderick, Alithia C.; Perros, Stephen G.; Shin, Naomi S.; Wells, Jenna L.; Davis, John B.; DiMaggio, Charles J.; Wang, Shuang; Tate, Simon N. Less PAIN. 157(10):2297-2308, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A structured interview and bedside physical tests capture the diversity of symptoms and signs in diabetic polyneuropathy and provide a pragmatic approach to phenotyping pain. Buy SDC
Electrical high-frequency stimulation of the human thoracolumbar fascia evokes long-term potentiation-like pain amplification Schilder, Andreas; Magerl, Walter; Hoheisel, Ulrich; More Schilder, Andreas; Magerl, Walter; Hoheisel, Ulrich; Klein, Thomas; Treede, Rolf-Detlef Less PAIN. 157(10):2309-2317, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The spinal input originating from the human thoracolumbar fascia is able to induce long-lasting changes in pain sensitivity likely contributing to non-specific low back pain. Buy
Expose or protect? A randomized controlled trial of exposure in vivo vs pain-contingent treatment as usual in patients with complex regional pain syndrome type 1 den Hollander, Marlies; Goossens, Mariëlle; de Jong, Jeroen; More den Hollander, Marlies; Goossens, Mariëlle; de Jong, Jeroen; Ruijgrok, Joop; Oosterhof, Jan; Onghena, Patrick; Smeets, Rob; Vlaeyen, Johan W. S. Less PAIN. 157(10):2318-2329, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: In CRPS-I patients with at least moderate levels of pain-related fear, exposure to daily activities is more effective than a pain-contingent treatment in reducing disability. Buy SDC
Electroencephalographic signatures of pain and analgesia in rats LeBlanc, Brian W.; Bowary, Paul M.; Chao, Yu-Chieh; More LeBlanc, Brian W.; Bowary, Paul M.; Chao, Yu-Chieh; Lii, Theresa R.; Saab, Carl Y. Less PAIN. 157(10):2330-2340, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pain increases EEG power and corticocortical coherence in different pain models, whereas analgesic treatments reverse these trends. Buy SDC
The impact of peripheral nerve blocks on perioperative outcome in hip and knee arthroplasty—a population-based study Memtsoudis, Stavros G.; Poeran, Jashvant; Cozowicz, Crispiana; More Memtsoudis, Stavros G.; Poeran, Jashvant; Cozowicz, Crispiana; Zubizarreta, Nicole; Ozbek, Umut; Mazumdar, Madhu Less PAIN. 157(10):2341-2349, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: In over 1 million orthopedic surgeries, peripheral nerve blocks were associated with beneficial outcomes, calling for further research to establish causality to support a broader utilization with potential benefits. Buy SDC
Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study Wodarski, Rachel; Delaney, Ada; Ultenius, Camilla; More Wodarski, Rachel; Delaney, Ada; Ultenius, Camilla; Morland, Rosie; Andrews, Nick; Baastrup, Catherine; Bryden, Luke A.; Caspani, Ombretta; Christoph, Thomas; Gardiner, Natalie J.; Huang, Wenlong; Kennedy, Jeffrey D.; Koyama, Suguru; Li, Dominic; Ligocki, Marcin; Lindsten, Annika; Machin, Ian; Pekcec, Anton; Robens, Angela; Rotariu, Sanziana M.; Voß, Sabrina; Segerdahl, Marta; Stenfors, Carina; Svensson, Camilla I.; Treede, Rolf-Detlef; Uto, Katsuhiro; Yamamoto, Kazumi; Rutten, Kris; Rice, Andrew S.C. Less PAIN. 157(10):2350-2365, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: This unique multicenter approach provides high-quality evidence validating burrowing as a robust and reproducible outcome measure to infer the global effect of pain on rodents. Go to Full Text of this Article Open SDC
Effects of topical combinations of clonidine and pentoxifylline on capsaicin-induced allodynia and postcapsaicin tourniquet-induced pain in healthy volunteers: a double-blind, randomized, controlled study Ragavendran, J. Vaigunda; Laferrière, André; Bennett, Gary J.; More Ragavendran, J. Vaigunda; Laferrière, André; Bennett, Gary J.; Ware, Mark A.; Gandhi, Wiebke; Bley, Keith; Schweinhardt, Petra; Coderre, Terence J. Less PAIN. 157(10):2366-2374, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Topical combination of clonidine and pentoxifylline, more effectively than single agents alone, alleviates postcapsaicin tourniquet-induced pain, as well as capsaicin-induced allodynia, in healthy human volunteers. Buy SDC
Impaired conditioned pain modulation in youth with functional abdominal pain Morris, Matthew C.; Walker, Lynn S.; Bruehl, Stephen; More Morris, Matthew C.; Walker, Lynn S.; Bruehl, Stephen; Stone, Amanda L.; Mielock, Alyssa S.; Rao, Uma Less PAIN. 157(10):2375-2381, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Findings suggest weaker conditioned pain modulation effects in youth with functional abdominal pain compared with healthy youth. Buy
Chronic physical illness in early life and risk of chronic widespread and regional pain at age 68: evidence from the 1946 British birth cohort Muthuri, Stella G.; Kuh, Diana; Bendayan, Rebecca; More Muthuri, Stella G.; Kuh, Diana; Bendayan, Rebecca; Macfarlane, Gary J.; Cooper, Rachel Less PAIN. 157(10):2382-2389, October 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: In a British birth cohort study, experience of serious illness in earlier life is associated with increased risk of chronic widespread pain at age 68. Go to Full Text of this Article Open SDC
Harnessing positive placebo effect and minimize negative nocebo effect: the art of a healing profession Ruan, Xiulu; Tran, Lien; Kaye, Alan David Ruan, Xiulu; Tran, Lien; Kaye, Alan David Less PAIN. 157(10):2390, October 2016. Favorite PDF Permissions Buy
Curcumin reduces pain in DOMS Drobnic, Franchek Drobnic, Franchek Less PAIN. 157(10):2390-2391, October 2016. Favorite PDF Permissions Buy
Reply Singla, Neil; Desjardins, Paul J. Singla, Neil; Desjardins, Paul J. Less PAIN. 157(10):2391, October 2016. Favorite PDF Permissions Buy
