Access to PAIN Reports is now open: IASP inaugurates a new journal Yarnitsky, David; Keefe, Francis J. Yarnitsky, David; Keefe, Francis J. Less PAIN. 157(9):1835, September 2016. Favorites PDF Get Content & Permissions Free
Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations Taylor, Ann M.; Phillips, Kristine; Patel, Kushang V.; More Taylor, Ann M.; Phillips, Kristine; Patel, Kushang V.; Turk, Dennis C.; Dworkin, Robert H.; Beaton, Dorcas; Clauw, Daniel J.; Gignac, Monique A.M.; Markman, John D.; Williams, David A.; Bujanover, Shay; Burke, Laurie B.; Carr, Daniel B.; Choy, Ernest H.; Conaghan, Philip G.; Cowan, Penney; Farrar, John T.; Freeman, Roy; Gewandter, Jennifer; Gilron, Ian; Goli, Veeraindar; Gover, Tony D.; Haddox, J. David; Kerns, Robert D.; Kopecky, Ernest A.; Lee, David A.; Malamut, Richard; Mease, Philip; Rappaport, Bob A.; Simon, Lee S.; Singh, Jasvinder A.; Smith, Shannon M.; Strand, Vibeke; Tugwell, Peter; Vanhove, Gertrude F.; Veasley, Christin; Walco, Gary A.; Wasan, Ajay D.; Witter, James Less PAIN. 157(9):1836-1850, September 2016. Abstract Abstract Favorites PDF Get Content & Permissions Buy
Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations Edwards, Robert R.; Dworkin, Robert H.; Turk, Dennis C.; More Edwards, Robert R.; Dworkin, Robert H.; Turk, Dennis C.; Angst, Martin S.; Dionne, Raymond; Freeman, Roy; Hansson, Per; Haroutounian, Simon; Arendt-Nielsen, Lars; Attal, Nadine; Baron, Ralf; Brell, Joanna; Bujanover, Shay; Burke, Laurie B.; Carr, Daniel; Chappell, Amy S.; Cowan, Penney; Etropolski, Mila; Fillingim, Roger B.; Gewandter, Jennifer S.; Katz, Nathaniel P.; Kopecky, Ernest A.; Markman, John D.; Nomikos, George; Porter, Linda; Rappaport, Bob A.; Rice, Andrew S.C.; Scavone, Joseph M.; Scholz, Joachim; Simon, Lee S.; Smith, Shannon M.; Tobias, Jeffrey; Tockarshewsky, Tina; Veasley, Christine; Versavel, Mark; Wasan, Ajay D.; Wen, Warren; Yarnitsky, David Less PAIN. 157(9):1851-1871, September 2016. Abstract Abstract Favorites PDF Get Content & Permissions Buy
Psychological interventions in managing postoperative pain in children: a systematic review Davidson, Fiona; Snow, Stephanie; Hayden, Jill A.; More Davidson, Fiona; Snow, Stephanie; Hayden, Jill A.; Chorney, Jill Less PAIN. 157(9):1872-1886, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This systematic review revealed that psychological interventions, particularly distraction/imagery, may be effective in the management of children's postoperative pain when measured in the short term. Buy SDC
Pain in acquired inflammatory demyelinating polyneuropathies Thakur, Siddarth; Dworkin, Robert H.; Freeman, Roy; More Thakur, Siddarth; Dworkin, Robert H.; Freeman, Roy; Gorson, Kenneth C.; Herrmann, David N. Less PAIN. 157(9):1887-1894, September 2016. Favorites PDF Get Content & Permissions Buy SDC
Cognitive behavioral training reverses the effect of pain exposure on brain network activity Kucyi, Aaron; Salomons, Tim V.; Davis, Karen D. Kucyi, Aaron; Salomons, Tim V.; Davis, Karen D. Less PAIN. 157(9):1895-1904, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Eight sessions of cognitive–behavioral training diminishes the effects of repeated noxious stimulation on the brain's default mode network response during pain. Buy
Effectiveness of dry needling for chronic nonspecific neck pain: a randomized, single-blinded, clinical trial Cerezo-Téllez, Ester; Torres-Lacomba, María; Fuentes-Gallardo, Isabel; More Cerezo-Téllez, Ester; Torres-Lacomba, María; Fuentes-Gallardo, Isabel; Perez-Muñoz, Milagros; Mayoral-del-Moral, Orlando; Lluch-Girbés, Enrique; Prieto-Valiente, Luis; Falla, Deborah Less PAIN. 157(9):1905-1917, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Deep dry needling of myofascial trigger points is an effective treatment for patients with chronic nonspecific neck pain. Buy
Predicting preschool pain-related anticipatory distress: the relative contribution of longitudinal and concurrent factors Racine, Nicole M.; Pillai Riddell, Rebecca R.; Flora, David B.; More Racine, Nicole M.; Pillai Riddell, Rebecca R.; Flora, David B.; Taddio, Anna; Garfield, Hartley; Greenberg, Saul Less PAIN. 157(9):1918-1932, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In a longitudinal cohort of parent–child dyads, parent behaviour from infancy and preschool are strongest predictors of anticipatory distress at preschool. Buy
Pharmacologic attenuation of cross-modal sensory augmentation within the chronic pain insula Harte, Steven E.; Ichesco, Eric; Hampson, Johnson P.; More Harte, Steven E.; Ichesco, Eric; Hampson, Johnson P.; Peltier, Scott J.; Schmidt-Wilcke, Tobias; Clauw, Daniel J.; Harris, Richard E. Less PAIN. 157(9):1933-1945, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Sensitivity to visual stimuli is increased in patients with fibromyalgia and improved with administration of pregabalin. Go to Full Text of this Article Open SDC
The reciprocal associations between catastrophizing and pain outcomes in patients being treated for neuropathic pain: a cross-lagged panel analysis study Racine, Mélanie; Moulin, Dwight E.; Nielson, Warren R.; More Racine, Mélanie; Moulin, Dwight E.; Nielson, Warren R.; Morley-Forster, Patricia K.; Lynch, Mary; Clark, Alexander J.; Stitt, Larry; Gordon, Allan; Nathan, Howard; Smyth, Catherine; Ware, Mark A.; Jensen, Mark P. Less PAIN. 157(9):1946-1953, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Decreases in catastrophizing early in chronic neuropathic pain treatment predicted a subsequent improvement of both pain intensity and interference and vice versa, suggesting mutual causation. Buy
Dipeptidyl peptidase-4 inhibitor use is not associated with elevated risk of severe joint pain in patients with type 2 diabetes: a population-based cohort study Hou, Wen-Hsuan; Chang, Kai-Cheng; Li, Chung-Yi; More Hou, Wen-Hsuan; Chang, Kai-Cheng; Li, Chung-Yi; Ou, Huang-Tz Less PAIN. 157(9):1954-1959, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The use of dipeptidyl peptidase-4 inhibitors slightly but non-significantly reduced the risk of severe joint pain in patients with type 2 diabetes. Buy SDC
Nociceptin/orphanin FQ receptor expression in clinical pain disorders and functional effects in cultured neurons Anand, Praveen; Yiangou, Yiangos; Anand, Uma; More Anand, Praveen; Yiangou, Yiangos; Anand, Uma; Mukerji, Gaurav; Sinisi, Marco; Fox, Michael; McQuillan, Anthony; Quick, Tom; Korchev, Yuri E.; Hein, Peter Less PAIN. 157(9):1960-1969, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: N/OFQ receptor (NOP) was found to be increased in bladder tissue from patients with painful bladder syndrome. Potent inhibition in cultured nociceptors indicates analgesic potential of NOP agonists. Buy
Perturbed connectivity of the amygdala and its subregions with the central executive and default mode networks in chronic pain Jiang, Ying; Oathes, Desmond; Hush, Julia; More Jiang, Ying; Oathes, Desmond; Hush, Julia; Darnall, Beth; Charvat, Mylea; Mackey, Sean; Etkin, Amit Less PAIN. 157(9):1970-1978, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Patients with chronic pain had heightened amygdala connectivity with central executive network, and those with most exaggerated amygdala–central executive network connectivity reported greatest pain catastrophizing. Buy SDC
The cortical response to a noxious procedure changes over time in preterm infants Bembich, Stefano; Marrazzo, Francesca; Barini, Alice; More Bembich, Stefano; Marrazzo, Francesca; Barini, Alice; Ravalico, Paola; Cont, Gabriele; Demarini, Sergio Less PAIN. 157(9):1979-1987, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The premature brain response to repeated nociceptive stimuli may be explained by both endogenous cortical maturation and experience-dependent neuroplasticity, triggered by repetitive noxious experience. Buy SDC
Pain sensitivity profiles in patients with advanced knee osteoarthritis Frey-Law, Laura A.; Bohr, Nicole L.; Sluka, Kathleen A.; More Frey-Law, Laura A.; Bohr, Nicole L.; Sluka, Kathleen A.; Herr, Keela; Clark, Charles R.; Noiseux, Nicolas O.; Callaghan, John J.; Zimmerman, M. Bridget; Rakel, Barbara A. Less PAIN. 157(9):1988-1999, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Quantitative sensory testing in individuals with advanced knee osteoarthritis resulted in 4 pain sensitivity components and 5 pain sensitivity profiles associated with differences in pain and function. Buy SDC
Nonpainful wide-area compression inhibits experimental pain Honigman, Liat; Bar-Bachar, Ofrit; Yarnitsky, David; More Honigman, Liat; Bar-Bachar, Ofrit; Yarnitsky, David; Sprecher, Elliot; Granovsky, Yelena Less PAIN. 157(9):2000-2011, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Upper limb experimental heat pain is attenuated by lower limb nonpainful compression pants in an area-dependent mode, and in correlation with conditioned pain modulation, in healthy controls. Go to Full Text of this Article Open SDC
Prior voluntary wheel running attenuates neuropathic pain Grace, Peter M.; Fabisiak, Timothy J.; Green-Fulgham, Suzanne M.; More Grace, Peter M.; Fabisiak, Timothy J.; Green-Fulgham, Suzanne M.; Anderson, Nathan D.; Strand, Keith A.; Kwilasz, Andrew J.; Galer, Erika L.; Walker, Frederick Rohan; Greenwood, Benjamin N.; Maier, Steven F.; Fleshner, Monika; Watkins, Linda R. Less PAIN. 157(9):2012-2023, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Prior voluntary wheel running prevented allodynia after sciatic chronic constriction injury and decreased neuroinflammation in the lumbar spinal dorsal horn, dorsal root ganglia, and injured sciatic nerve. Buy SDC
Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus Kimura, Masafumi; Eisenach, James C.; Hayashida, Ken-ichiro Kimura, Masafumi; Eisenach, James C.; Hayashida, Ken-ichiro Less PAIN. 157(9):2024-2032, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Gabapentin loses efficacy over time after neuropathic injury via downregulation of GLT-1 in the LC. Histone deacetylase inhibition can rescue this impaired efficacy. Buy
Pediatric-Collaborative Health Outcomes Information Registry (Peds-CHOIR): a learning health system to guide pediatric pain research and treatment Bhandari, Rashmi P.; Feinstein, Amanda B.; Huestis, Samantha E.; More Bhandari, Rashmi P.; Feinstein, Amanda B.; Huestis, Samantha E.; Krane, Elliot J.; Dunn, Ashley L.; Cohen, Lindsey L.; Kao, Ming C.; Darnall, Beth D.; Mackey, Sean C. Less PAIN. 157(9):2033-2044, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This is a foundation article describing the first application of Peds-CHOIR, a free, open-source learning health care system to guide research and precision pain medicine. Buy
Increased fronto-hippocampal connectivity in the Prrxl1 knockout mouse model of congenital hypoalgesia Monteiro, Clara; Cardoso-Cruz, Helder; Matos, Mariana; More Monteiro, Clara; Cardoso-Cruz, Helder; Matos, Mariana; Dourado, Margarida; Lima, Deolinda; Galhardo, Vasco Less PAIN. 157(9):2045-2056, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The Prrxl1-/- model of congenital hypoalgesia shows increased fronto-hippocampal functional connectivity, together with a phenotype of enhanced performance in memory tasks, and reduced fear responses. Buy SDC
A randomized, double-blind, positive-controlled, 3-way cross-over human experimental pain study of a TRPV1 antagonist (V116517) in healthy volunteers and comparison with preclinical profile Arendt-Nielsen, Lars; Harris, Steve; Whiteside, Garth T.; More Arendt-Nielsen, Lars; Harris, Steve; Whiteside, Garth T.; Hummel, Michele; Knappenberger, Terri; O'Keefe, Sarah; Kapil, Ram; Kyle, Don Less PAIN. 157(9):2057-2067, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: A TRPV1 antagonist and a COX-2 inhibitor were profiled using human experimental pain models. The TRPV1 antagonist inhibited capsaicin sensitization and the COX-2 inhibitor reduced UV-B sensitization. Buy
Thrombospondin-4 divergently regulates voltage-gated Ca2+ channel subtypes in sensory neurons after nerve injury Pan, Bin; Guo, Yuan; Wu, Hsiang-En; More Pan, Bin; Guo, Yuan; Wu, Hsiang-En; Park, John; Trinh, Van Nancy; Luo, Z. David; Hogan, Quinn H. Less PAIN. 157(9):2068-2080, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Thrombospondin-4, which increases in dorsal root ganglia after nerve injury, decreases calcium entry into sensory neurons through high-voltage–activated channels but increases influx through low-voltage–activated channels. Buy
Group II mGluRs suppress hyperexcitability in mouse and human nociceptors Davidson, Steve; Golden, Judith P.; Copits, Bryan A.; More Davidson, Steve; Golden, Judith P.; Copits, Bryan A.; Ray, Pradipta R.; Vogt, Sherri K.; Valtcheva, Manouela V.; Schmidt, Robert E.; Ghetti, Andrea; Price, Theodore J.; Gereau, Robert W. IV Less PAIN. 157(9):2081-2088, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Peripheral sensitization is blocked by activation of group II metabotropic glutamate receptors in both mouse and human sensory neurons. Buy
Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan Miki, Kenji; Murakami, Masato; Oka, Hiroshi; More Miki, Kenji; Murakami, Masato; Oka, Hiroshi; Onozawa, Kaname; Yoshida, Sadahiro; Osada, Kenichi Less PAIN. 157(9):2089-2096, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Twelve-week treatment with mirtazapine (30 mg/d) was effective and safe in controlling fibromyalgia pain in Japanese nonelderly adult patients without coexisting depression. Go to Full Text of this Article Open SDC
Ultramicronized palmitoylethanolamide in spinal cord injury neuropathic pain: a randomized, double-blind, placebo-controlled trial Andresen, Sven R.; Bing, Jette; Hansen, Rikke M.; More Andresen, Sven R.; Bing, Jette; Hansen, Rikke M.; Biering-Sørensen, Fin; Johannesen, Inger L.; Hagen, Ellen Merete; Rice, Andrew S. C.; Nielsen, Jørgen F.; Bach, Flemming W.; Finnerup, Nanna B. Less PAIN. 157(9):2097-2103, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This randomized controlled trial found no effect of ultramicronized palmitoylethanolamide as add-on-therapy on neuropathic pain after spinal cord injury. Buy SDC
Experimental pain phenotyping in community-dwelling individuals with knee osteoarthritis Cardoso, Josue S.; Riley, Joseph L. III; Glover, Toni; More Cardoso, Josue S.; Riley, Joseph L. III; Glover, Toni; Sibille, Kimberly T.; Bartley, Emily J.; Goodin, Burel R.; Bulls, Hailey W.; Herbert, Matthew; Addison, Adriana S.; Staud, Roland; Redden, David T.; Bradley, Laurence A.; Fillingim, Roger B.; Cruz-Almeida, Yenisel Less PAIN. 157(9):2104-2114, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Our results support the hypothesis that different phenotypic profiles exist within persons with knee osteoarthritis. Our experimental pain-based groupings differed in demographic, psychological, and clinical characteristics. Buy
Cognitive behavioral therapy for chronic pain is effective, but for whom? Broderick, Joan E.; Keefe, Francis J.; Schneider, Stefan; More Broderick, Joan E.; Keefe, Francis J.; Schneider, Stefan; Junghaenel, Doerte U.; Bruckenthal, Patricia; Schwartz, Joseph E.; Kaell, Alan T.; Caldwell, David S.; McKee, Daphne; Gould, Elaine Less PAIN. 157(9):2115-2123, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Moderators of treatment effects were analyzed in a large, randomized, controlled trial of Pain Coping Skills Training for osteoarthritis patients with chronic pain. Buy SDC
Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential Xie, Jennifer Y.; Chew, Lindsey A.; Yang, Xiaofang; More Xie, Jennifer Y.; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yuying; Qu, Chaoling; Wang, Yue; Federici, Lauren M.; Fitz, Stephanie D.; Ripsch, Matthew S.; Due, Michael R.; Moutal, Aubin; Khanna, May; White, Fletcher A.; Vanderah, Todd W.; Johnson, Philip L.; Porreca, Frank; Khanna, Rajesh Less PAIN. 157(9):2124-2140, September 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: R9-CBD3-A6K, a calcium-channel allosteric inhibitory peptide, reversed tactile hypersensitivity and relieved ongoing neuropathic pain after immediate or sustained subcutaneous administration in rats. Buy SDC
Persistent pain after breast cancer surgery Harmon, Dominic; Holmes, Lorraine Harmon, Dominic; Holmes, Lorraine Less PAIN. 157(9):2141, September 2016. Favorites PDF Get Content & Permissions Buy
Changing pain-related knowledge may or may not reduce pain and improve function through changes in catastrophising Costa, Daniel S.J. Costa, Daniel S.J. Less PAIN. 157(9):2141-2142, September 2016. Favorites PDF Get Content & Permissions Buy
Reply Lee, Hopin; McAuley, James H.; Hübscher, Markus; More Lee, Hopin; McAuley, James H.; Hübscher, Markus; Kamper, Steven J.; Traeger, Adrian C.; Moseley, G. Lorimer Less PAIN. 157(9):2142, September 2016. Favorites PDF Get Content & Permissions Buy
