Pain language and evaluation Gracely, Richard H. Gracely, Richard H. Less PAIN. 157(7):1369-1372, July 2016. Favorite PDF Permissions Buy
Acute analgesic effects of nicotine and tobacco in humans: a meta-analysis Ditre, Joseph W.; Heckman, Bryan W.; Zale, Emily L.; More Ditre, Joseph W.; Heckman, Bryan W.; Zale, Emily L.; Kosiba, Jesse D.; Maisto, Stephen A. Less PAIN. 157(7):1373-1381, July 2016. Abstract Abstract Favorite PDF Permissions Buy
Do we need a third mechanistic descriptor for chronic pain states? Kosek, Eva; Cohen, Milton; Baron, Ralf; More Kosek, Eva; Cohen, Milton; Baron, Ralf; Gebhart, Gerald F.; Mico, Juan-Antonio; Rice, Andrew S.C.; Rief, Winfried; Sluka, A. Kathleen Less PAIN. 157(7):1382-1386, July 2016. Favorite PDF Permissions Free SDC
Pain assessment in context: a state of the science review of the McGill pain questionnaire 40 years on Main, Chris J. Main, Chris J. Less PAIN. 157(7):1387-1399, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The MPQ questionnaires are re-appraised in the light of advances in clinical science pain assessment and measurement over the last 40 years. Buy SDC
Preoperative pain mechanisms assessed by cuff algometry are associated with chronic postoperative pain relief after total knee replacement Petersen, Kristian Kjær; Graven-Nielsen, Thomas; Simonsen, Ole; More Petersen, Kristian Kjær; Graven-Nielsen, Thomas; Simonsen, Ole; Laursen, Mogens Berg; Arendt-Nielsen, Lars Less PAIN. 157(7):1400-1406, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Patients with knee osteoarthritis with low conditioned pain modulation and high temporal summation have more pain 12 months after total knee replacement surgery. Buy
Quantitative sensory testing in classical trigeminal neuralgia—a blinded study in patients with and without concomitant persistent pain Younis, Samaira; Maarbjerg, Stine; Reimer, Maren; More Younis, Samaira; Maarbjerg, Stine; Reimer, Maren; Wolfram, Frauke; Olesen, Jes; Baron, Ralf; Bendtsen, Lars Less PAIN. 157(7):1407-1414, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Classical trigeminal neuralgia patients with no sensory abnormalities at neurological examination had bilateral hypoesthesia and hyperalgesia in the face. Buy
Differential pain modulation properties in central neuropathic pain after spinal cord injury Gruener, Hila; Zeilig, Gabi; Laufer, Yocheved; More Gruener, Hila; Zeilig, Gabi; Laufer, Yocheved; Blumen, Nava; Defrin, Ruth Less PAIN. 157(7):1415-1424, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pain modulation is differentially altered in central neuropathic pain (CNP); reduced descending inhibition is associated with the extent of CNP distribution, whereas hyperexcitability is associated with CNP intensity. Buy
Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women de Kruijf, Marjolein; Stolk, Lisette; Zillikens, M. Carola; More de Kruijf, Marjolein; Stolk, Lisette; Zillikens, M. Carola; de Rijke, Yolanda B.; Bierma-Zeinstra, Sita M.A.; Hofman, Albert; Huygen, Frank J.P.M.; Uitterlinden, Andre G.; van Meurs, Joyce B.J. Less PAIN. 157(7):1425-1431, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Lower sex hormone levels are associated with chronic musculoskeletal pain, independent from lifestyle and health-related factors, in community-dwelling elderly women. Buy SDC
Loss of inhibitory tone on spinal cord dorsal horn spontaneously and nonspontaneously active neurons in a mouse model of neuropathic pain Medrano, Maria Carmen; Dhanasobhon, Dhanasak; Yalcin, Ipek; More Medrano, Maria Carmen; Dhanasobhon, Dhanasak; Yalcin, Ipek; Schlichter, Rémy; Cordero-Erausquin, Matilde Less PAIN. 157(7):1432-1442, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: In vivo electrophysiological recordings demonstrate unambiguous and dramatic loss of spinal inhibitory transmission in the spinal cord of a mouse model of neuropathic pain. Buy
Chronic musculoskeletal complaints as a predictor of mortality—The HUNT study Åsberg, Anders N.; Stovner, Lars J.; Zwart, John-Anker; More Åsberg, Anders N.; Stovner, Lars J.; Zwart, John-Anker; Winsvold, Bendik S.; Heuch, Ingrid; Hagen, Knut Less PAIN. 157(7):1443-1447, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Individuals with chronic musculoskeletal complaints or chronic widespread musculoskeletal complaints should find reassurance knowing that their conditions do not represent a health hazard in the long run. Buy
(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology Moutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; More Moutal, Aubin; Chew, Lindsey A.; Yang, Xiaofang; Wang, Yue; Yeon, Seul Ki; Telemi, Edwin; Meroueh, Seeneen; Park, Ki Duk; Shrinivasan, Raghuraman; Gilbraith, Kerry B.; Qu, Chaoling; Xie, Jennifer Y.; Patwardhan, Amol; Vanderah, Todd W.; Khanna, May; Porreca, Frank; Khanna, Rajesh Less PAIN. 157(7):1448-1463, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: (S)-lacosamide blocks CRMP2 phosphorylation leading to reduced voltage-gated calcium activity. (S)-lacosamide demonstrates antinociceptive efficacy through actions on distinct classes of sensory neurons identified by constellation pharmacology. Buy SDC
The heterogeneity of headache patients who self-medicate: a cluster analysis approach Mehuys, Els; Paemeleire, Koen; Crombez, Geert; More Mehuys, Els; Paemeleire, Koen; Crombez, Geert; Adriaens, Els; Van Hees, Thierry; Demarche, Sophie; Christiaens, Thierry; Van Bortel, Luc; Van Tongelen, Inge; Remon, Jean-Paul; Boussery, Koen Less PAIN. 157(7):1464-1471, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Individuals with headache who self-medicate form a rather heterogenous group. Cluster analysis identified 3 subtypes exhibiting marked differences in prevalence of medication overuse. Buy
Depression in patients with chronic pain attending a specialised pain treatment centre: prevalence and impact on health care costs Rayner, Lauren; Hotopf, Matthew; Petkova, Hristina; More Rayner, Lauren; Hotopf, Matthew; Petkova, Hristina; Matcham, Faith; Simpson, Anna; McCracken, Lance M. Less PAIN. 157(7):1472-1479, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Depression in chronic pain is highly prevalent (60.8%) and is a significant predictor of poorer functioning, pain interference, reduced work status, and increased health care costs. Go to Full Text of this Article Open
Pain modulatory phenotypes differentiate subgroups with different clinical and experimental pain sensitivity Vaegter, Henrik B.; Graven-Nielsen, Thomas Vaegter, Henrik B.; Graven-Nielsen, Thomas Less PAIN. 157(7):1480-1488, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Subgrouping based on pronociceptive and antinociceptive mechanisms differentiates patients with chronic pain and patients with different clinical pain and experimental pain sensitivity. Buy
Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic noncancer pain: do different measures identify the same patients? Campbell, Gabrielle; Bruno, Raimondo; Lintzeris, Nicholas; More Campbell, Gabrielle; Bruno, Raimondo; Lintzeris, Nicholas; Cohen, Milton; Nielsen, Suzanne; Hall, Wayne; Larance, Briony; Mattick, Richard P.; Blyth, Fiona; Farrell, Michael; Degenhardt, Louisa Less PAIN. 157(7):1489-1498, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The “Addiction” concept used in pain medicine is broad and encompasses patients who may not be at high-risk of problematic opioid use. Buy SDC
A randomized controlled trial of gabapentin for chronic low back pain with and without a radiating component Atkinson, J. Hampton; Slater, Mark A.; Capparelli, Edmund V.; More Atkinson, J. Hampton; Slater, Mark A.; Capparelli, Edmund V.; Patel, Shetal M.; Wolfson, Tanya; Gamst, Anthony; Abramson, Ian S.; Wallace, Mark S.; Funk, Stephen D.; Rutledge, Thomas R.; Wetherell, Julie L.; Matthews, Scott C.; Zisook, Sidney; Garfin, Steven R. Less PAIN. 157(7):1499-1507, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Gabapentin is widely prescribed for chronic back pain. This randomized trial failed to find analgesic efficacy for either back or leg pain. Buy
Obstacles to activity pacing: assessment, relationship to activity and functioning Cane, Douglas; McCarthy, Mary; Mazmanian, Dwight Cane, Douglas; McCarthy, Mary; Mazmanian, Dwight Less PAIN. 157(7):1508-1514, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Various obstacles limit the use of activity pacing in managing chronic pain. Treatment may reduce some barriers increasing activity pacing and improving psychosocial functioning. Buy SDC
Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1 Wang, Sen; Joseph, John; Diatchenko, Luda; More Wang, Sen; Joseph, John; Diatchenko, Luda; Ro, Jin Y.; Chung, Man-Kyo Less PAIN. 157(7):1515-1524, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Five common nonsynonymous variants of TRPV1 show differential activation, permeation, and desensitization in an agonist-dependent manner. Buy
Trends in long-term opioid prescribing in primary care patients with musculoskeletal conditions: an observational database study Bedson, John; Chen, Ying; Hayward, Richard A.; More Bedson, John; Chen, Ying; Hayward, Richard A.; Ashworth, Julie; Walters, Kate; Dunn, Kate M.; Jordan, Kelvin P. Less PAIN. 157(7):1525-1531, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Long-term opioid use decreased from 2011, but the proportion of more potent opioids prescribed increased. Ongoing review of effectiveness and need for discontinuation is important. Go to Full Text of this Article Open SDC
Combination of pregabalin with duloxetine for fibromyalgia: a randomized controlled trial Gilron, Ian; Chaparro, Luis E.; Tu, Dongsheng; More Gilron, Ian; Chaparro, Luis E.; Tu, Dongsheng; Holden, Ronald R.; Milev, Roumen; Towheed, Tanveer; DuMerton-Shore, Deborah; Walker, Sarah Less PAIN. 157(7):1532-1540, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: This double-blind randomized controlled trial demonstrates improved outcomes with a duloxetine–pregabalin combination over either single drug for fibromyalgia. Buy
Epac–protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation Gu, Yanping; Li, Guangwen; Chen, Yong; More Gu, Yanping; Li, Guangwen; Chen, Yong; Huang, Li-Yen Mae Less PAIN. 157(7):1541-1550, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Protein kinase C alpha plays a major role in mediating Epac-dependent enhancement of purinergic P2X3R activity in dorsal root ganglion neurons after inflammation. Go to Full Text of this Article Open
Helping motivation and well-being of chronic pain couples: a daily diary study Kindt, Sara; Vansteenkiste, Maarten; Loeys, Tom; More Kindt, Sara; Vansteenkiste, Maarten; Loeys, Tom; Goubert, Liesbet Less PAIN. 157(7):1551-1562, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Motives underlying partners' helping behavior seem critical in understanding when and why daily provided help yields benefits for both partners and individuals with chronic pain. Buy
Brief time-based activity pacing instruction as a singular behavioral intervention was not effective in participants with symptomatic osteoarthritis Murphy, Susan L.; Kratz, Anna L.; Kidwell, Kelley; More Murphy, Susan L.; Kratz, Anna L.; Kidwell, Kelley; Lyden, Angela K.; Geisser, Michael E.; Williams, David A. Less PAIN. 157(7):1563-1573, July 2016. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Time-based activity pacing as a singular behavioral intervention did not improve outcomes. The interventions may not be appropriate for people with knee and hip osteoarthritis and would need refinements for further testing. Buy SDC
Measuring chronic pain Okkels, Niels; Kyle, Phillip Raphael; Bech, Per Okkels, Niels; Kyle, Phillip Raphael; Bech, Per Less PAIN. 157(7):1574, July 2016. Favorite PDF Permissions Buy
Reply Sullivan, Mark D.; Ballantyne, Jane Sullivan, Mark D.; Ballantyne, Jane Less PAIN. 157(7):1574-1575, July 2016. Favorite PDF Permissions Buy
What reliability can and cannot tell us about pain report and pain neuroimaging Letzen, Janelle E.; Boissoneault, Jeff; Sevel, Landrew S.; More Letzen, Janelle E.; Boissoneault, Jeff; Sevel, Landrew S.; Robinson, Michael E. Less PAIN. 157(7):1575-1576, July 2016. Favorite PDF Permissions Buy
Reply Wager, Tor D.; Woo, Choong-Wan Wager, Tor D.; Woo, Choong-Wan Less PAIN. 157(7):1576-1577, July 2016. Favorite PDF Permissions Buy
Human surrogate models of neuropathic pain: validity and limitations: Erratum Less PAIN. 157(7):1578, July 2016. Favorite PDF Permissions Free
July 2016 Issue Video Introduction Creator: Duration: 4:54 PAIN July 2016, Volume 157, Issue 7; Play Favorite
