The interpersonal function of pain: conserving multiple resources Vervoort, Tine; Trost, Zina Vervoort, Tine; Trost, Zina Less PAIN. 157(4):773-774, April 2016. Favorites PDF Get Content & Permissions Buy
Controlling for “confounders” in psychosocial pain research Sullivan, Michael J.L. Sullivan, Michael J.L. Less PAIN. 157(4):775-776, April 2016. Favorites PDF Get Content & Permissions Buy
Effectiveness of psychological interventions for chronic pain on health care use and work absence: systematic review and meta-analysis Pike, Andrew; Hearn, Leslie; de C Williams, Amanda C. Pike, Andrew; Hearn, Leslie; de C Williams, Amanda C. Less PAIN. 157(4):777-785, April 2016. Abstract Abstract Favorites PDF Get Content & Permissions Buy SDC
Keratinocytes as modulators of sensory afferent firing Ritter-Jones, Marsha; Najjar, Sarah; Albers, Kathryn M. Ritter-Jones, Marsha; Najjar, Sarah; Albers, Kathryn M. Less PAIN. 157(4):786-787, April 2016. Favorites PDF Get Content & Permissions Free SDC
What can evolutionary theory tell us about chronic pain? Williams, Amanda C. de C Williams, Amanda C. de C Less PAIN. 157(4):788-790, April 2016. Favorites PDF Get Content & Permissions Buy
Pain and the global burden of disease Rice, Andrew S.C.; Smith, Blair H.; Blyth, Fiona M. Rice, Andrew S.C.; Smith, Blair H.; Blyth, Fiona M. Less PAIN. 157(4):791-796, April 2016. Favorites PDF Get Content & Permissions Buy SDC
Vagus nerve stimulation inhibits cortical spreading depression Chen, Shih-Pin; Ay, Ilknur; Lopes de Morais, Andreia; More Chen, Shih-Pin; Ay, Ilknur; Lopes de Morais, Andreia; Qin, Tao; Zheng, Yi; Sadeghian, Homa; Oka, Fumiaki; Simon, Bruce; Eikermann-Haerter, Katharina; Ayata, Cenk Less PAIN. 157(4):797-805, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Vagus nerve stimulation is a novel nonpharmacologic treatment in migraine, the mechanism of which might be mediated by suppressing the susceptibility to cortical spreading depression. Buy SDC
Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice Liu, Tong; Han, Qingjian; Chen, Gang; More Liu, Tong; Han, Qingjian; Chen, Gang; Huang, Ya; Zhao, Lin-Xia; Berta, Temugin; Gao, Yong-Jing; Ji, Ru-Rong Less PAIN. 157(4):806-817, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Toll-like receptor 4 plays an important role in chronic pain. In this study, we show that spinal Toll-like receptor 4 also contributes to chronic itch, alloknesis, astrocyte activation, and central sensitization. Buy SDC
Complexity, comorbidity, and health care costs associated with chronic widespread pain in primary care Morales-Espinoza, Enma Marianela; Kostov, Belchin; Salami, Daniel Cararach; More Morales-Espinoza, Enma Marianela; Kostov, Belchin; Salami, Daniel Cararach; Perez, Zoe Herreras; Rosalen, Anna Pereira; Molina, Jacinto Ortiz; Paz, Luis Gonzalez-de; Momblona, Josep Miquel Sotoca; Àreu, Jaume Benavent; Brito-Zerón, Pilar; Ramos-Casals, Manuel; Sisó-Almirall, Antoni Less PAIN. 157(4):818-826, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Patient's profile with CWP is a sedentary woman with high rates of anxiety and depression, increased cardiovascular risk, higher expected mortality rate and increased costs. Buy SDC
Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development Moreau, Nathan; Mauborgne, Annie; Bourgoin, Sylvie; More Moreau, Nathan; Mauborgne, Annie; Bourgoin, Sylvie; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette B.; Villanueva, Luis; Pohl, Michel; Boucher, Yves Less PAIN. 157(4):827-839, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Local blockade of Hedgehog signaling in rat sciatic nerve mimicked enhanced endoneurial vascular permeability, local neuroinflammation, and mechanical allodynia emergence typically evoked by nerve injury. Buy
Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy Becerra, Lino; Aasted, Christopher M.; Boas, David A.; More Becerra, Lino; Aasted, Christopher M.; Boas, David A.; George, Edward; Yücel, Meryem A.; Kussman, Barry D.; Kelsey, Peter; Borsook, David Less PAIN. 157(4):840-848, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The results from this study indicate that near-infrared spectroscopy may be a suitable technology for continuous pain monitoring in patients undergoing sedation or anesthesia. Buy
Association of levels of opioid use with pain and activity interference among patients initiating chronic opioid therapy: a longitudinal study Turner, Judith A.; Shortreed, Susan M.; Saunders, Kathleen W.; More Turner, Judith A.; Shortreed, Susan M.; Saunders, Kathleen W.; LeResche, Linda; Von Korff, Michael Less PAIN. 157(4):849-857, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: At 1-year follow-up, pain and interference levels of regular/higher-dose and intermittent/lower-dose opioid users were similar, and worse than those of patients with minimal/no opioid use. Buy
Modification of COMT-dependent pain sensitivity by psychological stress and sex Meloto, Carolina B.; Bortsov, Andrey V.; Bair, Eric; More Meloto, Carolina B.; Bortsov, Andrey V.; Bair, Eric; Helgeson, Erika; Ostrom, Cara; Smith, Shad B.; Dubner, Ronald; Slade, Gary D.; Fillingim, Roger B.; Greenspan, Joel D.; Ohrbach, Richard; Maixner, William; McLean, Samuel A.; Diatchenko, Luda Less PAIN. 157(4):858-867, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: COMT genetic variants' effect on pain sensitivity is masked by stress and sex. Buy SDC
A possible neural mechanism for photosensitivity in chronic pain Martenson, Melissa E.; Halawa, Omar I.; Tonsfeldt, Karen J.; More Martenson, Melissa E.; Halawa, Omar I.; Tonsfeldt, Karen J.; Maxwell, Charlene A.; Hammack, Nora; Mist, Scott D.; Pennesi, Mark E.; Bennett, Robert M.; Mauer, Kim M.; Jones, Kim D.; Heinricher, Mary M. Less PAIN. 157(4):868-878, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: An unexpected finding of photosensitivity in pain-modulating neurons in the brain stem could contribute to multisensory hypersensitivity in patients with fibromyalgia, who demonstrated profound photosensitivity compared to healthy control subjects. Buy
Upregulation of the sodium channel NaVβ4 subunit and its contributions to mechanical hypersensitivity and neuronal hyperexcitability in a rat model of radicular pain induced by local dorsal root ganglion inflammation Xie, Wenrui; Tan, Zhi-Yong; Barbosa, Cindy; More Xie, Wenrui; Tan, Zhi-Yong; Barbosa, Cindy; Strong, Judith A.; Cummins, Theodore R.; Zhang, Jun-Ming Less PAIN. 157(4):879-891, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Knockdown of the regulatory subunit NaVβ4 reduced mechanical hypersensitivity and reduced neuronal hyperexcitability and resurgent current upregulation induced by local inflammation of the lumbar dorsal root ganglia. Buy SDC
Differences in demographic, clinical, and symptom characteristics and quality of life outcomes among oncology patients with different types of pain Posternak, Victoria; Dunn, Laura B.; Dhruva, Anand; More Posternak, Victoria; Dunn, Laura B.; Dhruva, Anand; Paul, Steven M.; Luce, Judith; Mastick, Judy; Levine, Jon D.; Aouizerat, Bradley E.; Hammer, Marylin; Wright, Fay; Miaskowski, Christine Less PAIN. 157(4):892-900, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In this study, 72.5% of the patients reported pain. Of the 671 who reported pain, 21.5% reported only noncancer pain, 37.0% only cancer pain, and 41.5% both cancer and noncancer pain. Buy
Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations Andrews, Nick A.; Latrémolière, Alban; Basbaum, Allan I.; More Andrews, Nick A.; Latrémolière, Alban; Basbaum, Allan I.; Mogil, Jeffrey S.; Porreca, Frank; Rice, Andrew S.C.; Woolf, Clifford J.; Currie, Gillian L.; Dworkin, Robert H.; Eisenach, James C.; Evans, Scott; Gewandter, Jennifer S.; Gover, Tony D.; Handwerker, Hermann; Huang, Wenlong; Iyengar, Smriti; Jensen, Mark P.; Kennedy, Jeffrey D.; Lee, Nancy; Levine, Jon; Lidster, Katie; Machin, Ian; McDermott, Michael P.; McMahon, Stephen B.; Price, Theodore J.; Ross, Sarah E.; Scherrer, Grégory; Seal, Rebecca P.; Sena, Emily S.; Silva, Elizabeth; Stone, Laura; Svensson, Camilla I.; Turk, Dennis C.; Whiteside, Garth Less PAIN. 157(4):901-909, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Improved reporting standards, and adoption of experimental protocols that emphasize control of experimental bias, are likely to improve understanding and confidence in pain biology. Go to Full Text of this Article Open
Protein kinase C-mediated mu-opioid receptor phosphorylation and desensitization in rats, and its prevention during early diabetes Mousa, Shaaban A.; Shaqura, Mohammed; Winkler, Jens; More Mousa, Shaaban A.; Shaqura, Mohammed; Winkler, Jens; Khalefa, Baled I.; Al-Madol, Mohammed A.; Shakibaei, Mehdi; Schulz, Stefan; Schäfer, Michael Less PAIN. 157(4):910-921, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This study focuses on opioid receptor phosphorylation in sensory neurons, which leads to a loss in opioid responsiveness during the early phase of diabetic neuropathy. Buy
Does changing pain-related knowledge reduce pain and improve function through changes in catastrophizing? Lee, Hopin; McAuley, James H.; Hübscher, Markus; More Lee, Hopin; McAuley, James H.; Hübscher, Markus; Kamper, Steven J.; Traeger, Adrian C.; Moseley, G. Lorimer Less PAIN. 157(4):922-930, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Explaining pain leads to long-term improvements in pain and function, but this effect is not mediated through changes in catastrophizing. Buy SDC
Chronic pain disorders in HIV primary care: clinical characteristics and association with healthcare utilization Jiao, Jocelyn M.; So, Eric; Jebakumar, Jebakaran; More Jiao, Jocelyn M.; So, Eric; Jebakumar, Jebakaran; George, Mary Catherine; Simpson, David M.; Robinson-Papp, Jessica Less PAIN. 157(4):931-937, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Chronic pain in HIV in the primary care setting is most commonly due to degenerative musculoskeletal disorders, and is associated with increased healthcare utilization. Buy SDC
Dyadic analysis of child and parent trait and state pain catastrophizing in the process of children's pain communication Birnie, Kathryn A.; Chambers, Christine T.; Chorney, Jill; More Birnie, Kathryn A.; Chambers, Christine T.; Chorney, Jill; Fernandez, Conrad V.; McGrath, Patrick J. Less PAIN. 157(4):938-948, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Observational study revealing intrapersonal and interpersonal influences of child and parent state pain catastrophizing on child verbal pain behaviours and parent ratings of child pain. Buy
Quantitative sensory testing and pain-evoked cytokine reactivity: comparison of patients with sickle cell disease to healthy matched controls Campbell, Claudia M.; Carroll, C. Patrick; Kiley, Kasey; More Campbell, Claudia M.; Carroll, C. Patrick; Kiley, Kasey; Han, Dingfen; Haywood, Carlton Jr; Lanzkron, Sophie; Swedberg, Lauren; Edwards, Robert R.; Page, Gayle G.; Haythornthwaite, Jennifer A. Less PAIN. 157(4):949-956, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Patients with sickle cell disease showed moderate pain sensitivity and enhanced reactivity to several cytokines, a vasoactive peptide, and a neuropeptide compared to healthy controls. Buy
Sleep problems and pain: a longitudinal cohort study in emerging adults Bonvanie, Irma J.; Oldehinkel, Albertine J.; Rosmalen, Judith G.M.; More Bonvanie, Irma J.; Oldehinkel, Albertine J.; Rosmalen, Judith G.M.; Janssens, Karin A.M. Less PAIN. 157(4):957-963, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Sleep problems predicted long-term chronic pain and an increase in musculoskeletal pain severity, especially in females, but not headache or abdominal pain severity. Buy
High-resolution transcriptome analysis reveals neuropathic pain gene-expression signatures in spinal microglia after nerve injury Jeong, Heejin; Na, Young-Ji; Lee, Kihwan; More Jeong, Heejin; Na, Young-Ji; Lee, Kihwan; Kim, Yong Ho; Lee, Yunsin; Kang, Minho; Jiang, Bao-Chun; Yeom, Young Il; Wu, Long-Jun; Gao, Yong-Jing; Kim, Junhyong; Oh, Seog Bae Less PAIN. 157(4):964-976, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: High-resolution transcriptome analysis with spinal microglia revealed miRNA29-c and Gria1 as critical factors for microglial activation and neuropathic pain development after peripheral nerve injury. Buy SDC
Recombinant neural progenitor transplants in the spinal dorsal horn alleviate chronic central neuropathic pain Jergova, Stanislava; Gajavelli, Shyam; Pathak, Nirmal; More Jergova, Stanislava; Gajavelli, Shyam; Pathak, Nirmal; Sagen, Jacqueline Less PAIN. 157(4):977-989, April 2016. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Genetically modified rat embryonic GABAergic cells releasing an NMDA receptor antagonist attenuate pain-related behavior in the spinal cord injury–induced pain model. Buy SDC
Unexplained resolution of diagnosed hypogonadism Daniell, Harry W. Daniell, Harry W. Less PAIN. 157(4):990, April 2016. Favorites PDF Get Content & Permissions Buy
Reply Basaria, Shehzad; Edwards, Robert R.; Travison, Thomas G. Basaria, Shehzad; Edwards, Robert R.; Travison, Thomas G. Less PAIN. 157(4):990-991, April 2016. Favorites PDF Get Content & Permissions Buy