In Memoriam Jean-Marie Besson 1938 to 2014 Bouhassira, Didier; Villanueva, Luis Bouhassira, Didier; Villanueva, Luis Less PAIN. 156(12):2399-2401, December 2015. Favorites PDF Get Content & Permissions Buy
Should we use gabapentin for postoperative pain control? Fletcher, Dominique; Martinez, Valéria Fletcher, Dominique; Martinez, Valéria Less PAIN. 156(12):2402-2403, December 2015. Favorites PDF Get Content & Permissions Buy
Importance of knowing your stimulation paradigm: methodological considerations on laser-evoked pain responses in rats and humans Hess, Andreas Hess, Andreas Less PAIN. 156(12):2404-2405, December 2015. Favorites PDF Get Content & Permissions Buy
Diversity of composition and function of sodium channels in peripheral sensory neurons Dib-Hajj, Sulayman D.; Waxman, Stephen G. Dib-Hajj, Sulayman D.; Waxman, Stephen G. Less PAIN. 156(12):2406-2407, December 2015. Favorites PDF Get Content & Permissions Free
Men, masculinity, and pain Keogh, Edmund Keogh, Edmund Less PAIN. 156(12):2408-2412, December 2015. Favorites PDF Get Content & Permissions Buy
Predictive factors for the development of persistent pain after breast cancer surgery Andersen, Kenneth Geving; Duriaud, Helle Molter; Jensen, Helle Elisabeth; More Andersen, Kenneth Geving; Duriaud, Helle Molter; Jensen, Helle Elisabeth; Kroman, Niels; Kehlet, Henrik Less PAIN. 156(12):2413-2422, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Prospective study of 537 patients treated for breast cancer. Both patient- and treatment-related risk factors predict persistent pain at 1 year. Buy
Quality assurance for Quantitative Sensory Testing laboratories: development and validation of an automated evaluation tool for the analysis of declared healthy samples Vollert, Jan; Mainka, Tina; Baron, Ralf; More Vollert, Jan; Mainka, Tina; Baron, Ralf; Enax-Krumova, Elena K.; Hüllemann, Philipp; Maier, Christoph; Pfau, Doreen Barbara; Tölle, Thomas; Treede, Rolf-Detlef Less PAIN. 156(12):2423-2430, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Quantitative Sensory Testing assessment of groups of healthy subjects is applied for quality control of new Quantitative Sensory Testing laboratories. Buy
Chloride dysregulation and inhibitory receptor blockade yield equivalent disinhibition of spinal neurons yet are differentially reversed by carbonic anhydrase blockade Lee, Kwan Yeop; Prescott, Steven A. Lee, Kwan Yeop; Prescott, Steven A. Less PAIN. 156(12):2431-2437, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Disinhibition caused by chloride dysregulation is reversed by blockade of carbonic anhydrase with acetazolamide, whereas disinhibition caused by GABAA or glycine receptor blockade is not. Buy
Analgesic and sedative effects of perioperative gabapentin in total knee arthroplasty: a randomized, double-blind, placebo-controlled dose-finding study Lunn, Troels Haxholdt; Husted, Henrik; Laursen, Mogens Berg; More Lunn, Troels Haxholdt; Husted, Henrik; Laursen, Mogens Berg; Hansen, Lars Tambour; Kehlet, Henrik Less PAIN. 156(12):2438-2448, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Gabapentin may have limited role in acute postoperative pain management of opioid-naive patients undergoing total knee arthroplasty and should not be recommended as standard of care. Buy
Was it a pain or a sound? Across-species variability in sensory sensitivity Hu, Li; Xia, Xiaolei L.; Peng, Weiwei W.; More Hu, Li; Xia, Xiaolei L.; Peng, Weiwei W.; Su, Wenxin X.; Luo, Fei; Yuan, Hong; Chen, Antao T.; Liang, Meng; Iannetti, Giandomenico Less PAIN. 156(12):2449-2457, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Valid translation of experimental results from animals to humans critically relies on a careful consideration of differences in sensory sensitivity across species. Go to Full Text of this Article Open SDC
A phase 3, multicenter, randomized, double-blind, placebo-controlled, safety, tolerability, and efficacy study of Xtampza ER in patients with moderate-to-severe chronic low back pain Katz, Nathaniel; Kopecky, Ernest A.; O'Connor, Melinda; More Katz, Nathaniel; Kopecky, Ernest A.; O'Connor, Melinda; Brown, Robert H.; Fleming, Alison B. Less PAIN. 156(12):2458-2467, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This 12-week enriched-enrollment randomized-withdrawal clinical trial shows that Xtampza ER, a novel extended-release opioid with abuse-deterrent features, is an efficacious analgesic in patients with moderate-to-severe chronic low back pain. Buy SDC
Heightened cold pain and pressure pain sensitivity in young female adults with moderate-to-severe menstrual pain Slater, Helen; Paananen, Markus; Smith, Anne J.; More Slater, Helen; Paananen, Markus; Smith, Anne J.; O'Sullivan, Peter; Briggs, Andrew M.; Hickey, Martha; Mountain, Jenny; Karppinen, Jaro; Beales, Darren Less PAIN. 156(12):2468-2478, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Heightened pain sensitivity in young women with moderate-to-severe menstrual pain remains significant after adjusting for potential confounding variables, highlighting the need for innovative treatment. Buy SDC
Roles of prefrontal cortex and paraventricular thalamus in affective and mechanical components of visceral nociception Jurik, Angela; Auffenberg, Eva; Klein, Sabine; More Jurik, Angela; Auffenberg, Eva; Klein, Sabine; Deussing, Jan M.; Schmid, Roland M.; Wotjak, Carsten T.; Thoeringer, Christoph K. Less PAIN. 156(12):2479-2491, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Experimental pancreatitis induces a specific pattern of nociceptive behaviors in mice, notably affective responses that are mediated by the prefrontal cortex and midline thalamus. Buy SDC
Histamine H4 receptor activation alleviates neuropathic pain through differential regulation of ERK, JNK, and P38 MAPK phosphorylation Sanna, Maria D.; Stark, Holger; Lucarini, Laura; More Sanna, Maria D.; Stark, Holger; Lucarini, Laura; Ghelardini, Carla; Masini, Emanuela; Galeotti, Nicoletta Less PAIN. 156(12):2492-2504, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Histamine H4 receptor modulation might have a broader role in pain states than those secondary to inflammation. Histamine H4 receptor agonists could be a promising treatment of neuropathic pain. Buy SDC
Learned control over spinal nociception reduces supraspinal nociception as quantified by late somatosensory evoked potentials Ruscheweyh, Ruth; Bäumler, Maximilian; Feller, Moritz; More Ruscheweyh, Ruth; Bäumler, Maximilian; Feller, Moritz; Krafft, Stefanie; Sommer, Jens; Straube, Andreas Less PAIN. 156(12):2505-2513, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The present results suggest that during RIII feedback training, subjects learn to activate their descending pain inhibition. Buy SDC
Protein kinase C gamma-mediated phosphorylation of GluA1 in the postsynaptic density of spinal dorsal horn neurons accompanies neuropathic pain, and dephosphorylation by calcineurin is associated with prolonged analgesia Miletic, Gordana; Hermes, Jessie L.; Bosscher, Georgia L.; More Miletic, Gordana; Hermes, Jessie L.; Bosscher, Georgia L.; Meier, Brenton M.; Miletic, Vjekoslav Less PAIN. 156(12):2514-2520, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Protein kinase C gamma-mediated persistent phosphorylation of a-amino-3-hydroxy-5-methyl-4-isoxazolepropioinic acid receptors in the postsynaptic density of spinal dorsal horn neurons may elicit neuropathic pain because of the loss of calcineurin dephosphorylating activity. Buy
The influence of offset analgesia on the onset and offset of pain in patients with fibromyalgia Oudejans, Linda C.J.; Smit, Jeff M.; van Velzen, Monique; More Oudejans, Linda C.J.; Smit, Jeff M.; van Velzen, Monique; Dahan, Albert; Niesters, Marieke Less PAIN. 156(12):2521-2527, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Patients diagnosed with fibromyalgia have a reduced offset analgesia and adaptation response that influences both the onset and offset of pain. Buy
Involvement of peripheral artemin signaling in tongue pain: possible mechanism in burning mouth syndrome Shinoda, Masamichi; Takeda, Mamoru; Honda, Kuniya; More Shinoda, Masamichi; Takeda, Mamoru; Honda, Kuniya; Maruno, Mitsuru; Katagiri, Ayano; Satoh-Kuriwada, Shizuko; Shoji, Noriaki; Tsuchiya, Masahiro; Iwata, Koichi Less PAIN. 156(12):2528-2537, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The upregulation of TRPV1 in trigeminal ganglion neurons innervating tongue via GFRa3-mediated signaling contributes heat hypersensitivity observed in a mouse model of burning mouth syndrome. Buy
Preoperative dexamethasone reduces acute but not sustained pain after lumbar disk surgery: a randomized, blinded, placebo-controlled trial Nielsen, Rikke V.; Siegel, Hanna; Fomsgaard, Jonna S.; More Nielsen, Rikke V.; Siegel, Hanna; Fomsgaard, Jonna S.; Andersen, Johnny D.H.; Martusevicius, Robertas; Mathiesen, Ole; Dahl, Jørgen B. Less PAIN. 156(12):2538-2544, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Preoperative dexamethasone significantly reduced pain during mobilization and vomiting after lumbar disk surgery. No significant effects on sustained pain or complications 3 months postoperatively. Buy
Somatosensory assessment and conditioned pain modulation in temporomandibular disorders pain patients Kothari, Simple Futarmal; Baad-Hansen, Lene; Oono, Yuka; More Kothari, Simple Futarmal; Baad-Hansen, Lene; Oono, Yuka; Svensson, Peter Less PAIN. 156(12):2545-2555, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Somatosensory abnormalities were commonly detected in TMD pain patients and CPM effects were similar in TMD pain patients and healthy controls. Buy
Inhibition of the primary sensorimotor cortex by topical anesthesia of the forearm in patients with complex regional pain syndrome Strauss, Sebastian; Grothe, Matthias; Usichenko, Taras; More Strauss, Sebastian; Grothe, Matthias; Usichenko, Taras; Neumann, Nicola; Byblow, Winston D.; Lotze, Martin Less PAIN. 156(12):2556-2561, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Cutaneous anesthesia of the forearm in patients with complex regional pain syndrome was used to increase intracortical inhibition and decrease impaired spatial tactile resolution of the affected limb. Buy SDC
Conditioned place preference and spontaneous dorsal horn neuron activity in chronic constriction injury model in rats Dalm, Brian D.; Reddy, Chandan G.; Howard, Matthew A.; More Dalm, Brian D.; Reddy, Chandan G.; Howard, Matthew A.; Kang, Sinyoung; Brennan, Timothy J. Less PAIN. 156(12):2562-2571, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Spontaneous nociception, tested by conditioned place preference, and spontaneous dorsal horn neuron activity were not evident in the rat model of chronic constriction injury to the sciatic nerve. Buy
Wnt/Ryk signaling contributes to neuropathic pain by regulating sensory neuron excitability and spinal synaptic plasticity in rats Liu, Su; Liu, Yue-Peng; Huang, Zhi-Jiang; More Liu, Su; Liu, Yue-Peng; Huang, Zhi-Jiang; Zhang, Yan-Kai; Song, Angela A.; Ma, Ping-Chuan; Song, Xue-Jun Less PAIN. 156(12):2572-2584, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Ryk receptor-mediated Wnt signaling pathway is critical to sensitization of the peripheral sensory neurons and spinal dorsal horn neurons after nerve injury. Buy
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness Cohen, Steven P.; Peterlin, B. Lee; Fulton, Larry; More Cohen, Steven P.; Peterlin, B. Lee; Fulton, Larry; Neely, Edward T.; Kurihara, Connie; Gupta, Anita; Mali, Jimmy; Fu, Diana C.; Jacobs, Michael B.; Plunkett, Anthony R.; Verdun, Aubrey J.; Stojanovic, Milan P.; Hanling, Steven; Constantinescu, Octav; White, Ronald L.; McLean, Brian C.; Pasquina, Paul F.; Zhao, Zirong Less PAIN. 156(12):2585-2594, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In this double-blind, multicenter, comparative-effectiveness study, we found that pulsed radiofrequency provided better pain relief than steroid injections in patients with occipital neuralgia. Buy
Role of brainstem serotonin in analgesia produced by low-intensity exercise on neuropathic pain after sciatic nerve injury in mice Bobinski, Franciane; Ferreira, Tamara A.A.; Córdova, Marina M.; More Bobinski, Franciane; Ferreira, Tamara A.A.; Córdova, Marina M.; Dombrowski, Patrícia A.; da Cunha, Cláudio; Santo, Caroline C. do Espírito; Poli, Anicleto; Pires, Rita G.W.; Martins-Silva, Cristina; Sluka, Kathleen A.; Santos, Adair R.S. Less PAIN. 156(12):2595-2606, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This study shows that analgesia produced by 2 weeks of low-intensity exercise after peripheral nerve injury in mice is dependent on serotonergic neurotransmission on brainstem. Buy
Construct validity and reliability of a real-time multidimensional smartphone app to assess pain in children and adolescents with cancer Stinson, Jennifer N.; Jibb, Lindsay A.; Nguyen, Cynthia; More Stinson, Jennifer N.; Jibb, Lindsay A.; Nguyen, Cynthia; Nathan, Paul C.; Maloney, Anne Marie; Dupuis, L. Lee; Gerstle, J. Ted; Hopyan, Sevan; Alman, Benjamin A.; Strahlendorf, Caron; Portwine, Carol; Johnston, Donna L. Less PAIN. 156(12):2607-2615, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: The construct validity and internal consistency reliability of a real-time data capture app to assess pain in children and adolescents with cancer has been demonstrated. Go to Full Text of this Article Open SDC
Increasing placebo responses over time in U.S. clinical trials of neuropathic pain Tuttle, Alexander H.; Tohyama, Sarasa; Ramsay, Tim; More Tuttle, Alexander H.; Tohyama, Sarasa; Ramsay, Tim; Kimmelman, Jonathan; Schweinhardt, Petra; Bennett, Gary J.; Mogil, Jeffrey S. Less PAIN. 156(12):2616-2626, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Placebo responses in clinical trials of neuropathic pain have increased considerably over 1990 to 2013. This trend has been driven by studies conducted in the United States. Buy SDC
Contributions of physical function and satisfaction with social roles to emotional distress in chronic pain: a Collaborative Health Outcomes Information Registry (CHOIR) study Sturgeon, John A.; Dixon, Eric A.; Darnall, Beth D.; More Sturgeon, John A.; Dixon, Eric A.; Darnall, Beth D.; Mackey, Sean C. Less PAIN. 156(12):2627-2633, December 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Pain intensity affects anger and depression sequentially, distally through disrupted physical function and more proximally through disruptions in satisfaction with social roles and activities. Buy SDC
Importance of quantifying indirect effects from mediation analyses Lee, Hopin; Hübscher, Markus; McAuley, James H. Lee, Hopin; Hübscher, Markus; McAuley, James H. Less PAIN. 156(12):2634-2635, December 2015. Favorites PDF Get Content & Permissions Buy
Further verification by bootstrapped mediation analyses that pain catastrophizing modulates pain report but not spinal nociception: a reply to Lee, Hübscher, and McAuley Rhudy, Jamie L.; Terry, Ellen L. Rhudy, Jamie L.; Terry, Ellen L. Less PAIN. 156(12):2635-2636, December 2015. Favorites PDF Get Content & Permissions Buy
Construct validity and reliability of a real-time multidimensional smartphone app to assess pain in children and adolescents with cancer Creator: Stinson, Jennifer N.; Jibb, Lindsay A.; Nguyen, Cynthia; Nathan, Paul C.; Maloney, Anne Marie; Dupuis, L. Lee; Gerstle, J. Ted; Hopyan, Sevan; Alman, Benjamin A.; Strahlendorf, Caron; Portwine, Carol; Johnston, Donna L Duration: 5:09 Journal: PAIN December 2015, Volume 156, Issue 12; Show More Show Less We evaluated the construct validity, reliability, and feasibility of the Pain Squad multidimensional smartphone-based pain assessment application in children and adolescents with cancer, using 2 descriptive studies with repeated measures. Play Video | + Favorites
