Local anesthetics take a central action in analgesia Zeilhofer, Hanns Ulrich; Schmelz, Martin Zeilhofer, Hanns Ulrich; Schmelz, Martin Less PAIN. 156(9):1579-1580, September 2015. Favorites PDF Get Content & Permissions Buy
The puzzle of attentional bias to pain: beyond attention Crombez, Geert; Heathcote, Lauren C.; Fox, Elaine Crombez, Geert; Heathcote, Lauren C.; Fox, Elaine Less PAIN. 156(9):1581-1582, September 2015. Favorites PDF Get Content & Permissions Buy
Primary preventive effects of a multifaceted workplace intervention on low back pain van der Beek, Allard J. van der Beek, Allard J. Less PAIN. 156(9):1583-1584, September 2015. Favorites PDF Get Content & Permissions Buy
Running from pain: mechanisms of exercise-mediated prevention of neuropathic pain Bonin, Robert P. Bonin, Robert P. Less PAIN. 156(9):1585-1586, September 2015. Favorites PDF Get Content & Permissions Buy
Frozen shoulder and corticosteroids—still a need for needles? Kvarstein, Gunnvald Kvarstein, Gunnvald Less PAIN. 156(9):1587-1588, September 2015. Favorites PDF Get Content & Permissions Buy
Towards a new model of attentional biases in the development, maintenance, and management of pain Todd, Jemma; Sharpe, Louise; Johnson, Ameika; More Todd, Jemma; Sharpe, Louise; Johnson, Ameika; Nicholson Perry, Kathryn; Colagiuri, Ben; Dear, Blake F. Less PAIN. 156(9):1589-1600, September 2015. Abstract Abstract Favorites PDF Get Content & Permissions Buy SDC
Transcranial magnetic stimulation of the brain: guidelines for pain treatment research Klein, Max M.; Treister, Roi; Raij, Tommi; More Klein, Max M.; Treister, Roi; Raij, Tommi; Pascual-Leone, Alvaro; Park, Lawrence; Nurmikko, Turo; Lenz, Fred; Lefaucheur, Jean-Pascal; Lang, Magdalena; Hallett, Mark; Fox, Michael; Cudkowicz, Merit; Costello, Ann; Carr, Daniel B.; Ayache, Samar S.; Oaklander, Anne Louise Less PAIN. 156(9):1601-1614, September 2015. Abstract Abstract Favorites PDF Get Content & Permissions Buy
Reporting of IMMPACT-recommended core outcome domains among trials assessing opioids for chronic non-cancer pain Mulla, Sohail M.; Maqbool, Amna; Sivananthan, Laxsanaa; More Mulla, Sohail M.; Maqbool, Amna; Sivananthan, Laxsanaa; Lopes, Luciane C.; Schandelmaier, Stefan; Kamaleldin, Mostafa; Hsu, Sandy; Riva, John J.; Vandvik, Per Olav; Tsoi, Ludwig; Lam, Tommy; Ebrahim, Shanil; Johnston, Bradley C.; Olivieri, Lori; Montoya, Luis; Kunz, Regina; Scheidecker, Anne; Buckley, D. Norman; Sessler, Daniel I.; Guyatt, Gordon H.; Busse, Jason W. Less PAIN. 156(9):1615-1619, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Among clinical trials of opioids for chronic non-cancer pain, reporting of 9 IMMPACT-recommended outcome domains ranged from 99% for pain to 7% for interpersonal functioning. Buy SDC
Induction of thermal and mechanical hypersensitivity by parathyroid hormone–related peptide through upregulation of TRPV1 function and trafficking Mickle, Aaron D.; Shepherd, Andrew J.; Loo, Lipin; More Mickle, Aaron D.; Shepherd, Andrew J.; Loo, Lipin; Mohapatra, Durga P. Less PAIN. 156(9):1620-1636, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Cellular and molecular mechanisms underlying parathyroid hormone–related peptide-induced nociceptor sensitization and induction of thermal and mechanical hypersensitivity through upregulation of transient receptor potential vanilloid-1 function and trafficking. Buy SDC
Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7 Namer, Barbara; Ørstavik, Kristin; Schmidt, Roland; More Namer, Barbara; Ørstavik, Kristin; Schmidt, Roland; Kleggetveit, Inge-Petter; Weidner, Christian; Mørk, Cato; Kvernebo, Mari Skylstad; Kvernebo, Knut; Salter, Hugh; Carr, Thomas Hedley; Segerdahl, Märta; Quiding, Hans; Waxman, Stephen George; Handwerker, Hermann Otto; Torebjörk, Hans Erik; Jørum, Ellen; Schmelz, Martin Less PAIN. 156(9):1637-1646, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Axonal depolarization may counteract gain-of-function of Nav1.7 mutations under resting conditions, but upon activity-dependent hyperpolarization, Nav1.7 is deinactivating and thus can facilitate severe pain attacks in patients with erythromelalgia. Buy
The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain Werdehausen, Robert; Mittnacht, Sebastian; Bee, Lucy A.; More Werdehausen, Robert; Mittnacht, Sebastian; Bee, Lucy A.; Minett, Michael S.; Armbruster, Anja; Bauer, Inge; Wood, John N.; Hermanns, Henning; Eulenburg, Volker Less PAIN. 156(9):1647-1659, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: The lidocaine metabolite N-ethylglycine specifically reduces GlyT1-dependent glycine uptake and has antinociceptive effects in experimental inflammatory and neuropathic pain, while no adverse effects are observed. Go to Full Text of this Article Open SDC
A randomized double-blind, placebo-controlled efficacy and safety study of ALO-02 (extended-release oxycodone surrounding sequestered naltrexone) for moderate-to-severe chronic low back pain treatment Rauck, Richard L.; Hale, Martin E.; Bass, Almasa; More Rauck, Richard L.; Hale, Martin E.; Bass, Almasa; Bramson, Candace; Pixton, Glenn; Wilson, Jacquelyn G.; Setnik, Beatrice; Meisner, Paul; Sommerville, Kenneth W.; Malhotra, Bimal K.; Wolfram, Gernot Less PAIN. 156(9):1660-1669, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: ALO-02, an abuse-deterrent formulation containing pellets of extended-release oxycodone hydrochloride surrounding sequestered naltrexone hydrochloride, was efficacious and tolerated in a similar manner to other opioids in treating chronic low back pain. Buy
The role of spatial frequency information in the recognition of facial expressions of pain Wang, Shan; Eccleston, Christopher; Keogh, Edmund Wang, Shan; Eccleston, Christopher; Keogh, Edmund Less PAIN. 156(9):1670-1682, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Both low– and high–spatial frequency information make the recognition of pain expressions possible, with low–spatial frequency information playing a more prominent role. Buy
Ultrasound-guided intra-articular and rotator interval corticosteroid injections in adhesive capsulitis of the shoulder: a double-blind, sham-controlled randomized study Prestgaard, Tore; Wormgoor, Marjon E.A.; Haugen, Simen; More Prestgaard, Tore; Wormgoor, Marjon E.A.; Haugen, Simen; Harstad, Herlof; Mowinckel, Petter; Brox, Jens Ivar Less PAIN. 156(9):1683-1691, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In the treatment of adhesive capsulitis, ultrasound-guided corticosteroid intra-articular injection or combined intra-articular/rotator interval corticosteroid injection was similarly effective for at least 12 weeks. Buy
Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer Thompson, Michelle L.; Jimenez-Andrade, Juan M.; Chartier, Stephane; More Thompson, Michelle L.; Jimenez-Andrade, Juan M.; Chartier, Stephane; Tsai, James; Burton, Elizabeth A.; Habets, Gaston; Lin, Paul S.; West, Brian L.; Mantyh, Patrick W. Less PAIN. 156(9):1692-1702, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Inhibition of myeloid lineage attenuates bone cancer pain and disease progression. Buy SDC
Efficacy and safety of tanezumab in the treatment of pain from bone metastases Sopata, Maciej; Katz, Nathaniel; Carey, William; More Sopata, Maciej; Katz, Nathaniel; Carey, William; Smith, Michael D.; Keller, David; Verburg, Kenneth M.; West, Christine R.; Wolfram, Gernot; Brown, Mark T. Less PAIN. 156(9):1703-1713, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Two phase 2 trials indicate tanezumab may provide additional sustained analgesia in patients with metastatic bone pain despite daily opioid use. Buy
Subpopulations of PKCγ interneurons within the medullary dorsal horn revealed by electrophysiologic and morphologic approach Alba-Delgado, Cristina; El Khoueiry, Corinne; Peirs, Cédric; More Alba-Delgado, Cristina; El Khoueiry, Corinne; Peirs, Cédric; Dallel, Radhouane; Artola, Alain; Antri, Myriam Less PAIN. 156(9):1714-1728, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: At least 2 functionally and morphologically distinct subpopulations of PKCγ+ interneurons coexist in the medullary dorsal horn, which might play different roles in tactile allodynia processing. Buy SDC
Behavioral and electrophysiological abnormalities in two rat models of antiretroviral drug-induced neuropathy Garcia-Perez, Elizabeth; Solà, Romà; Sumalla, Mireia; More Garcia-Perez, Elizabeth; Solà, Romà; Sumalla, Mireia; Serra, Jordi Less PAIN. 156(9):1729-1736, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Animal models of antiretroviral-induced neuropathy differ in the effects on peripheral nerves. Abnormalities affect both large and small nerve fibers. Buy
CXCR3 chemokine receptor signaling mediates itch in experimental allergic contact dermatitis Qu, Lintao; Fu, Kai; Yang, Jennifer; More Qu, Lintao; Fu, Kai; Yang, Jennifer; Shimada, Steven G.; LaMotte, Robert H. Less PAIN. 156(9):1737-1746, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In a murine model of allergic contact dermatitis, the chemokine CXCL10, acting on the receptor CXCR3, directly activates cutaneous sensory neurons to elicit itch. Buy
Use of aspirin combinations with caffeine and increasing headache frequency: a prospective population-based study Schramm, Sara H.; Moebus, Susanne; Özyurt Kugumcu, Melek; More Schramm, Sara H.; Moebus, Susanne; Özyurt Kugumcu, Melek; Geisel, Marie H.; Obermann, Mark; Yoon, Min-Suk; Diener, Hans-Christoph; Jöckel, Karl-Heinz; Katsarava, Zaza Less PAIN. 156(9):1747-1754, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: This study reveals no evidence that aspirin combined with caffeine is a risk factor for increasing headache frequency or promoting the development of chronic headache. Buy
The posterior medial cortex in urologic chronic pelvic pain syndrome: detachment from default mode network—a resting-state study from the MAPP Research Network Martucci, Katherine T.; Shirer, William R.; Bagarinao, Epifanio; More Martucci, Katherine T.; Shirer, William R.; Bagarinao, Epifanio; Johnson, Kevin A.; Farmer, Melissa A.; Labus, Jennifer S.; Apkarian, A. Vania; Deutsch, Georg; Harris, Richard E.; Mayer, Emeran A.; Clauw, Daniel J.; Greicius, Michael D.; Mackey, Sean C. Less PAIN. 156(9):1755-1764, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In chronic pelvic pain, the posterior cingulate cortex is functionally detached from the default mode network and instead joined to pain and emotion processing regions. Buy SDC
Chronic pain in the pelvic area or lower extremities after rectal cancer treatment and its impact on quality of life: a population-based cross-sectional study Feddern, Marie-Louise; Jensen, Troels Staehelin; Laurberg, Søren Feddern, Marie-Louise; Jensen, Troels Staehelin; Laurberg, Søren Less PAIN. 156(9):1765-1771, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Chronic pain in the pelvic area and lower extremities is a common late complication to rectal cancer treatment with impact on quality of life. Buy SDC
Brain mechanisms supporting violated expectations of pain Zeidan, Fadel; Lobanov, Oleg V.; Kraft, Robert A.; More Zeidan, Fadel; Lobanov, Oleg V.; Kraft, Robert A.; Coghill, Robert C. Less PAIN. 156(9):1772-1785, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The left posterior parietal cortex is activated when expectations of an impending noxious stimulus are violated by a large discrepancy between expected and experienced pain. Buy SDC
A multifaceted workplace intervention for low back pain in nurses' aides: a pragmatic stepped wedge cluster randomised controlled trial Rasmussen, Charlotte Diana Nørregaard; Holtermann, Andreas; Bay, Hans; More Rasmussen, Charlotte Diana Nørregaard; Holtermann, Andreas; Bay, Hans; Søgaard, Karen; Birk Jørgensen, Marie Less PAIN. 156(9):1786-1794, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: A multifaceted workplace intervention with participatory ergonomics, cognitive–behavioural training, and physical training was effective in reducing low back pain days, intensity, and bothersomeness. Go to Full Text of this Article Open
Predictors of the placebo analgesia response in randomized controlled trials of chronic pain: a meta-analysis of the individual data from nine industrially sponsored trials Vase, Lene; Vollert, Jan; Finnerup, Nanna B.; More Vase, Lene; Vollert, Jan; Finnerup, Nanna B.; Miao, Xiaopeng; Atkinson, Gary; Marshall, Scott; Nemeth, Robert; Lange, Bernd; Liss, Charlie; Price, Donald D.; Maier, Christoph; Jensen, Troels S.; Segerdahl, Märta Less PAIN. 156(9):1795-1802, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Expectancy-related factors significantly predicted the placebo response in randomized controlled trials. Buy
Diffuse noxious inhibitory controls and nerve injury: restoring an imbalance between descending monoamine inhibitions and facilitations Bannister, Kirsty; Patel, Ryan; Goncalves, Leonor; More Bannister, Kirsty; Patel, Ryan; Goncalves, Leonor; Townson, Louisa; Dickenson, Anthony H. Less PAIN. 156(9):1803-1811, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Diffuse noxious inhibitory controls (DNICs) are reduced after neuropathy. α2 adrenoceptor- and 5-HT3 receptor-mediated mechanisms underlie DNIC because drugs that modulate these receptors restore DNIC-mediated inhibition after neuropathy. Buy
Early increasing-intensity treadmill exercise reduces neuropathic pain by preventing nociceptor collateral sprouting and disruption of chloride cotransporters homeostasis after peripheral nerve injury López-Álvarez, Víctor M.; Modol, Laura; Navarro, Xavier; More López-Álvarez, Víctor M.; Modol, Laura; Navarro, Xavier; Cobianchi, Stefano Less PAIN. 156(9):1812-1825, September 2015. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Specific treadmill exercise reduces neuropathic pain by modulating neurotrophin expression that induces collateral sprouting and disruption of NKCC1 and KCC2 homeostasis after sciatic nerve injury. Buy
Do genetic factors improve prediction of postherniotomy pain? Macfarlane, Gary J. Macfarlane, Gary J. Less PAIN. 156(9):1826, September 2015. Favorites PDF Get Content & Permissions Buy
Reply Belfer, Inna Belfer, Inna Less PAIN. 156(9):1826, September 2015. Favorites PDF Get Content & Permissions Buy
Diagnostic requirements are necessary before dry needling in the treatment of chronic pain Fleckenstein, Johannes Fleckenstein, Johannes Less PAIN. 156(9):1827, September 2015. Favorites PDF Get Content & Permissions Buy
Reply Sterling, Michele; Vicenzino, Bill; Souvlis, Tina Sterling, Michele; Vicenzino, Bill; Souvlis, Tina Less PAIN. 156(9):1827-1828, September 2015. Favorites PDF Get Content & Permissions Buy
Concern regarding use of the term “nonhuman animals” in the article “Ontogeny and phylogeny of facial expression of pain” Cooke, Gavan M. Cooke, Gavan M. Less PAIN. 156(9):1828, September 2015. Favorites PDF Get Content & Permissions Buy
Reply Mogil, Jeffrey S.; Chambers, Christine T. Mogil, Jeffrey S.; Chambers, Christine T. Less PAIN. 156(9):1828-1829, September 2015. Favorites PDF Get Content & Permissions Buy
