PAIN

Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming
Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain
The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits
Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice
Nerve injury increases native Ca_V2.2 trafficking in dorsal root ganglion mechanoreceptors
Towards harmonizing the concepts and definitions of pain in the World Health Organization's Family of International Classifications

Current Issue Highlights

Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain

Caspi, Yaki; Mazar, Michael; Kushnir, Yishai; More

PAIN. 164(6):1388-1401, June 2023.

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Neuroendocrine mechanisms in oxaliplatin-induced hyperalgesic priming

Staurengo-Ferrari, Larissa; Araldi, Dionéia; Green, Paul G.; More

PAIN. 164(6):1375-1387, June 2023.

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Understanding the concurrent and predictive relations between child-led emotion regulation behaviors and pain during vaccination in toddlerhood

Gennis, Hannah G.; Flora, David B.; Norton, Lucas; More

PAIN. 164(6):1291-1302, June 2023.

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Nerve injury increases native Ca_V2.2 trafficking in dorsal root ganglion mechanoreceptors

Nieto-Rostro, Manuela; Patel, Ryan; Dickenson, Anthony H.; More

PAIN. 164(6):1264-1279, June 2023.

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The genesis of the unequal burden of pain: a selective review examining social inequities and unheard voices

Green, Carmen Renee

PAIN. 164(6):1258-1263, June 2023.

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Towards harmonizing the concepts and definitions of pain in the World Health Organization's Family of International Classifications

Reneman, Michiel F.; Selb, Melissa; Korwisi, Beatrice; More

PAIN. 164(6):1240-1244, June 2023.

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Do “central sensitization” questionnaires reflect measures of nociceptive sensitization or psychological constructs? A systematic review and meta-analyses

Adams, Greig R.; Gandhi, Wiebke; Harrison, Richard; More

PAIN. 164(6):1222-1239, June 2023.

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2023 Global Year for Integrative Pain Care

Welcome to the 2023 Global Year for Integrative Pain Care. This year's theme aims to raise awareness about integrative pain care and illustrate the knowns and unknowns of this important topic via different initiatives, including a fact sheet series and several webinars.

Articles published in PAIN related to this year's theme are marked with the Global Year logo and added to an article collection.

Call for papers relevant to COVID-19

PAIN is issuing calls for papers relevant to the global COVID-19 pandemic.

PAIN is seeking both basic and applied science papers addressing pain-related topics of importance to the pandemic. PAIN seeks submissions that fit the following types of articles: Clinical and Basic Science Research Reports, Clinical Notes, Epidemiology, Comprehensive Reviews, Narrative Reviews, and Systematic Reviews. All submissions are subject to peer review. Manuscripts should be submitted here.

IASP Remembers Ronald Dubner, DDS, PhD

Ronald Dubner, DDS, PhD

12 October 1934 – 22 January 2023

Ronald Dubner, DDS, PhD, passed away in Bethesda, Maryland on 22 January 2023. Ron pioneered orofacial pain research during his years at the National Institutes of Health and the University of Maryland. He was a past Editor-in-Chief of PAIN, past IASP Councilor and a colleague and mentor to many IASP members. His passing represents a momentous loss to the pain field in general, and to the orofacial pain field specifically. He will be greatly missed.

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Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming

Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain

The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits

Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice

Nerve injury increases native Ca_V2.2 trafficking in dorsal root ganglion mechanoreceptors

Towards harmonizing the concepts and definitions of pain in the World Health Organization's Family of International Classifications

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Current Issue Highlights

Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain

In Brief:

Neuroendocrine mechanisms in oxaliplatin-induced hyperalgesic priming

In Brief:

Understanding the concurrent and predictive relations between child-led emotion regulation behaviors and pain during vaccination in toddlerhood

In Brief:

Nerve injury increases native Ca_V2.2 trafficking in dorsal root ganglion mechanoreceptors

In Brief:

The genesis of the unequal burden of pain: a selective review examining social inequities and unheard voices

Towards harmonizing the concepts and definitions of pain in the World Health Organization's Family of International Classifications

Do “central sensitization” questionnaires reflect measures of nociceptive sensitization or psychological constructs? A systematic review and meta-analyses

2023 Global Year for Integrative Pain Care

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Call for papers relevant to COVID-19

IASP Remembers Ronald Dubner, DDS, PhD

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Video Summary – August 2016 Issue