ArticlesInternet-enhanced management of fibromyalgia: A randomized controlled trialWilliams, David A.a,*; Kuper, Davidb; Segar, Michellec; Mohan, Nivedithad; Sheth, Manishe; Clauw, Daniel J.fAuthor Information aAnesthesiology, Medicine, Psychiatry, and Psychology, The University of Michigan, USA bAvera Research Institute, The Avera McKennan Hosptial and Health Center, Sioux Falls, SD, USA cInstitute for Research on Women and Gender, The University of Michigan, USA dMedicine, The University of Pittsburgh, USA eThe Avera McKennan Hosptial and Health Center, Sioux Falls, SD, USA fAnesthesiology, Medicine, and Psychiatry, The University of Michigan, USA *Corresponding author. Address: Chronic Pain and Fatigue Research Center, University of Michigan, 24 Frank Lloyd Wright Drive, Lobby M, Ann Arbor, MI 48106, USA. Tel.: +1 734 998 6961; fax: +1 734 998 6900. E-mail address:[email protected] Submitted March 30, 2010; revised August 5, 2010; accepted August 20, 2010. Pain: December 2010 - Volume 151 - Issue 3 - p 694-702 doi: 10.1016/j.pain.2010.08.034 Buy Metrics Abstract Both pharmacological and non-pharmacological interventions have demonstrated efficacy in the management of fibromyalgia (FM). Non-pharmacological interventions however are far less likely to be used in clinical settings, in part due to limited access. This manuscript presents the findings of a randomized controlled trail of an Internet-based exercise and behavioral self-management program for FM designed for use in the context of a routine clinical care. 118 individuals with FM were randomly assigned to either (a) standard care or (b) standard care plus access to a Web-Enhanced Behavioral Self-Management program (WEB-SM) grounded in cognitive and behavioral pain management principles. Individuals were assessed at baseline and again at 6 months for primary endpoints: reduction of pain and an improvement in physical functioning. Secondary outcomes included fatigue, sleep, anxiety and depressive symptoms, and a patient global impression of improvement. Individuals assigned to the WEB-SM condition reported significantly greater improvement in pain, physical functioning, and overall global improvement. Exercise and relaxation techniques were the most commonly used skills throughout the 6 month period. A no-contact, Internet-based, self-management intervention demonstrated efficacy on key outcomes for FM. While not everyone is expected to benefit from this approach, this study demonstrated that non-pharmacological interventions can be efficiently integrated into routine clinical practice with positive outcomes. © 2010 Lippincott Williams & Wilkins, Inc.