Is health-related quality of life a useful outcome in pain intervention research? Costa, Daniel S.J. Costa, Daniel S.J. Less PAIN. 161(1):1-2, January 2020. Favorites PDF Get Content & Permissions Buy
Rescue and concomitant analgesics in placebo-controlled trials of pharmacotherapy for neuropathic pain and low back pain Grøvle, Lars; Hasvik, Eivind; Haugen, Anne Julsrud Grøvle, Lars; Hasvik, Eivind; Haugen, Anne Julsrud Less PAIN. 161(1):3-10, January 2020. Abstract Abstract Favorites PDF Get Content & Permissions Go to Full Text of this Article Free SDC
Neurotransmitter systems involved in placebo and nocebo effects in healthy participants and patients with chronic pain: a systematic review Skyt, Ina; Lunde, Sigrid J.; Baastrup, Cathrine; More Skyt, Ina; Lunde, Sigrid J.; Baastrup, Cathrine; Svensson, Peter; Jensen, Troels S.; Vase, Lene Less PAIN. 161(1):11-23, January 2020. Abstract Abstract Favorites PDF Get Content & Permissions Go to Full Text of this Article Free SDC
Systematic review and meta-analysis of placebo/sham controlled randomised trials of spinal cord stimulation for neuropathic pain Duarte, Rui V.; Nevitt, Sarah; McNicol, Ewan; More Duarte, Rui V.; Nevitt, Sarah; McNicol, Ewan; Taylor, Rod S.; Buchser, Eric; North, Richard B.; Eldabe, Sam Less PAIN. 161(1):24-35, January 2020. Abstract Abstract Favorites PDF Get Content & Permissions Go to Full Text of this Article Free SDC
Translating clinical trials into improved real-world management of pain: convergence of translational, population-based, and primary care research Gilron, Ian; Blyth, Fiona; Smith, Blair H. Gilron, Ian; Blyth, Fiona; Smith, Blair H. Less PAIN. 161(1):36-42, January 2020. Favorites PDF Get Content & Permissions Buy
Targeting network hubs with noninvasive brain stimulation in patients with fibromyalgia Kaplan, Chelsea M.; Harris, Richard E.; Lee, UnCheol; More Kaplan, Chelsea M.; Harris, Richard E.; Lee, UnCheol; DaSilva, Alexandre F.; Mashour, George A.; Harte, Steven E. Less PAIN. 161(1):43-46, January 2020. Favorites PDF Get Content & Permissions Buy
MicroRNA-19b predicts widespread pain and posttraumatic stress symptom risk in a sex-dependent manner following trauma exposure Linnstaedt, Sarah D.; Rueckeis, Cathleen A.; Riker, Kyle D.; More Linnstaedt, Sarah D.; Rueckeis, Cathleen A.; Riker, Kyle D.; Pan, Yue; Wu, Alan; Yu, Shan; Wanstrath, Britannia; Gonzalez, Michael; Harmon, Evan; Green, Paul; Chen, Chieh V.; King, Tony; Lewandowski, Christopher; Hendry, Phyllis L.; Pearson, Claire; Kurz, Michael C.; Datner, Elizabeth; Velilla, Marc-Anthony; Domeier, Robert; Liberzon, Israel; Mogil, Jeffrey S.; Levine, Jon; McLean, Samuel A. Less PAIN. 161(1):47-60, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Translational research approaches identified miR-19b as a potential miRNA regulatory hub for posttraumatic widespread pain and posttraumatic stress symptoms that is expressed differently in males and females after trauma/stress exposure Buy SDC
Peripheral brain-derived neurotrophic factor contributes to chronic osteoarthritis joint pain Gowler, Peter R.W.; Li, Li; Woodhams, Stephen G.; More Gowler, Peter R.W.; Li, Li; Woodhams, Stephen G.; Bennett, Andrew J.; Suzuki, Rie; Walsh, David A.; Chapman, Victoria Less PAIN. 161(1):61-73, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Brain-derived neurotrophic factor is expressed in human osteoarthritis synovia. These data provide evidence for its importance as a mediator of osteoarthritis pain. Buy SDC
Upregulation of cortical GABAA receptor concentration in fibromyalgia Pomares, Florence B.; Roy, Steve; Funck, Thomas; More Pomares, Florence B.; Roy, Steve; Funck, Thomas; Feier, Natasha A.; Thiel, Alexander; Fitzcharles, Mary-Ann; Schweinhardt, Petra Less PAIN. 161(1):74-82, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: A widespread upregulation of cortical GABAA receptors was observed using [18F]flumazenil positron emission tomography in fibromyalgia patients, which correlated with functioning and pain. Go to Full Text of this Article Open SDC
Psychometric properties of Short Form-36 Health Survey, EuroQol 5-dimensions, and Hospital Anxiety and Depression Scale in patients with chronic pain LoMartire, Riccardo; Äng, Björn Olov; Gerdle, Björn; More LoMartire, Riccardo; Äng, Björn Olov; Gerdle, Björn; Vixner, Linda Less PAIN. 161(1):83-95, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: This large-sample item response theory-based evaluation assessed the measurement properties of SF-36, EQ-5D, and hospital anxiety and depression scale for chronic pain patients in clinical settings. Go to Full Text of this Article Open SDC
Epigenetic reduction of miR-214-3p upregulates astrocytic colony-stimulating factor-1 and contributes to neuropathic pain induced by nerve injury Liu, Lian; Xu, Dan; Wang, Tao; More Liu, Lian; Xu, Dan; Wang, Tao; Zhang, Yi; Yang, Xijing; Wang, Xiangxiu; Tang, Yuying Less PAIN. 161(1):96-108, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: In summary, our data indicated that DNMT3a-mediated epigenetic reduction of miR-214-3p upregulated astrocytic colony-stimulating factor-1 and contributed to the development of neuropathic pain. Buy SDC
Pain as a predictor of frailty over time among older Mexican Americans Sodhi, Jaspreet K.; Karmarkar, Amol; Raji, Mukaila; More Sodhi, Jaspreet K.; Karmarkar, Amol; Raji, Mukaila; Markides, Kyriakos S.; Ottenbacher, Kenneth J.; Al Snih, Soham Less PAIN. 161(1):109-113, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: In summary, our study determines that nonfrail older Mexican Americans with pain are more likely to experience frailty over time than those without pain. Go to Full Text of this Article Free SDC
Machine-learning–based knowledge discovery in rheumatoid arthritis–related registry data to identify predictors of persistent pain Lötsch, Jörn; Alfredsson, Lars; Lampa, Jon Lötsch, Jörn; Alfredsson, Lars; Lampa, Jon Less PAIN. 161(1):114-126, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: A machine-learning–based workflow was developed for the analysis of risk factors for persistent pain in data acquired from disease- and pain-related registries. Go to Full Text of this Article Free SDC
Adoptive immunotherapy with autologous T-cell infusions reduces opioid requirements in advanced cancer patients Zhou, Xinna; Qiao, Guoliang; Ren, Jun; More Zhou, Xinna; Qiao, Guoliang; Ren, Jun; Wang, Xiaoli; Wang, Shuo; Zhu, Siyu; Yuan, Yanhua; Morse, Michael A.; Hobeika, Amy; Lyerly, Herbert Kim Less PAIN. 161(1):127-134, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Adoptive cellular therapy could reduce cancer pain severity, opioid consumption, and improved immune parameters in the management of severe or refractory cancer pain. Buy
The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects Cavallone, Laura F.; Montana, Michael C.; Frey, Karen; More Cavallone, Laura F.; Montana, Michael C.; Frey, Karen; Kallogjeri, Dorina; Wages, James M.; Rodebaugh, Thomas L.; Doshi, Tina; Kharasch, Evan D.; Gereau, Robert W. IV Less PAIN. 161(1):135-146, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: We did not observe any persistent analgesic effect of the mGlu5 antagonist fenobam. In healthy volunteers, oral fenobam was well tolerated and showed highly variable disposition. Go to Full Text of this Article Free SDC
Neuromas and postamputation pain Buch, Nina Stockfleth; Qerama, Erisela; Brix Finnerup, Nanna; More Buch, Nina Stockfleth; Qerama, Erisela; Brix Finnerup, Nanna; Nikolajsen, Lone Less PAIN. 161(1):147-155, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Ultrasound-verified swollen neuromas are equally present in amputees with and without postamputation pain. Buy
Heightened risk of pain in young adult women with a history of childhood maltreatment: a prospective longitudinal study Beal, Sarah J.; Kashikar-Zuck, Susmita; King, Christopher; More Beal, Sarah J.; Kashikar-Zuck, Susmita; King, Christopher; Black, William; Barnes, Jaclyn; Noll, Jennie G. Less PAIN. 161(1):156-165, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: This study examined associations between childhood maltreatment and pain in young adult women; adolescent post-traumatic stress symptoms partially explained relations between maltreatment and subsequent pain. Go to Full Text of this Article Free SDC
Spared nerve injury differentially alters parabrachial monosynaptic excitatory inputs to molecularly specific neurons in distinct subregions of the central amygdala Li, Jun-Nan; Sheets, Patrick L. Li, Jun-Nan; Sheets, Patrick L. Less PAIN. 161(1):166-176, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Using viral optogenetics in transgenic reporter mice, it was revealed that spared nerve injury model of neuropathic pain differentially alters synaptic efficacy of monosynaptic parabrachial inputs targeting distinct regions and neurons in the central amygdala. Go to Full Text of this Article Open
Sexually dimorphic therapeutic response in bortezomib-induced neuropathic pain reveals altered pain physiology in female rodents Stockstill, Katherine; Wahlman, Carrie; Braden, Kathryn; More Stockstill, Katherine; Wahlman, Carrie; Braden, Kathryn; Chen, Zhoumou; Yosten, Gina L.; Tosh, Dilip K.; Jacobson, Kenneth A.; Doyle, Timothy M.; Samson, Willis K.; Salvemini, Daniela Less PAIN. 161(1):177-184, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: We have found that there are sexually dimorphic responses to S1PR1 antagonists and A3AR agonists for the treatment of bortezomib-induced neuropathic pain. Buy
Selective-cold output through a distinct subset of lamina I spinoparabrachial neurons Hachisuka, Junichi; Koerber, H. Richard; Ross, Sarah E. Hachisuka, Junichi; Koerber, H. Richard; Ross, Sarah E. Less PAIN. 161(1):185-194, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Cold output from the spinal cord to the parabrachial nucleus is mediated by a specific cell type with distinct properties. Buy
Are there really only 2 kinds of people in the world? Evaluating the distribution of change from baseline in pain clinical trials Mbowe, Omar B.; Gewandter, Jennifer S.; Turk, Dennis C.; More Mbowe, Omar B.; Gewandter, Jennifer S.; Turk, Dennis C.; Dworkin, Robert H.; McDermott, Michael P. Less PAIN. 161(1):195-201, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: An investigation into the claim that changes in pain intensity from baseline have a bimodal distribution was conducted. No evidence of bimodality was found. Buy SDC
Innate immune response to bacterial urinary tract infection sensitises high-threshold bladder afferents and recruits silent nociceptors Brierley, Stuart M.; Goh, Kelvin G.K.; Sullivan, Matthew J.; More Brierley, Stuart M.; Goh, Kelvin G.K.; Sullivan, Matthew J.; Moore, Kate H.; Ulett, Glen C.; Grundy, Luke Less PAIN. 161(1):202-210, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: The innate immune response to E. coli-induced urinary tract infection sensitises “high-threshold” mechanosensitive bladder afferent neurons to initiate pelvic pain during bladder distension. Buy SDC
Foot shock stress generates persistent widespread hypersensitivity and anhedonic behavior in an anxiety-prone strain of mice Wu, Pau Yen; Yang, Xiaofang; Wright, Douglas E.; More Wu, Pau Yen; Yang, Xiaofang; Wright, Douglas E.; Christianson, Julie A. Less PAIN. 161(1):211-219, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions In Brief: Stress exposure in an anxiety-prone mouse strain recapitulates many symptoms observed in patients with urologic chronic pain, including bladder and widespread hypersensitivity and anhedonia. Buy
The association of early life stressors with pain sensitivity and pain experience at 22 years Waller, Robert; Smith, Anne J.; O'Sullivan, Peter B.; More Waller, Robert; Smith, Anne J.; O'Sullivan, Peter B.; Slater, Helen; Sterling, Michele; Straker, Leon M. Less PAIN. 161(1):220-229, January 2020. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Go to Full Text of this Article In Brief: Early life is a critical period of development, with this investigation reporting an association between early life stress and future pain sensitivity. Go to Full Text of this Article Free
Abnormal medial prefrontal cortex functional connectivity and its association with clinical symptoms in chronic low back pain: Erratum Less PAIN. 161(1):230-231, January 2020. Favorites PDF Get Content & Permissions Free
Thank you to PAIN reviewers Less PAIN. 161(1):232-235, January 2020. Favorites PDF Get Content & Permissions Buy
