Clarifying our cultural contest about chronic pain Sullivan, Mark D. Sullivan, Mark D. Less PAIN. 160(2):279-280, February 2019. Favorites PDF Get Content & Permissions
Pain that does not interfere with daily life—a new focus for population epidemiology and public health? Jordan, Kelvin P.; Sim, Julius; Croft, Peter; More Jordan, Kelvin P.; Sim, Julius; Croft, Peter; Blyth, Fiona Less PAIN. 160(2):281-285, February 2019. Favorites PDF Get Content & Permissions
Structural, functional, and symptom relations in painful distal symmetric polyneuropathies: a systematic review Karlsson, Pall; Hincker, Alexander M.; Jensen, Troels Staehelin; More Karlsson, Pall; Hincker, Alexander M.; Jensen, Troels Staehelin; Freeman, Roy; Haroutounian, Simon Less PAIN. 160(2):286-297, February 2019. Abstract Abstract Favorites PDF Get Content & Permissions Abstract:
Social representations of chronic pain in newspapers, online media, and film Kugelmann, Robert; Watson, Kelsey; Frisby, Gregory Kugelmann, Robert; Watson, Kelsey; Frisby, Gregory Less PAIN. 160(2):298-306, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Qualitative analysis of newspaper articles, memes, video blogs, and a film explored how social representations of chronic pain are produced and reproduced.
Dual enkephalinase inhibitor PL265: a novel topical treatment to alleviate corneal pain and inflammation Reaux-Le Goazigo, Annabelle; Poras, Hervé; Ben-Dhaou, Cyrine; More Reaux-Le Goazigo, Annabelle; Poras, Hervé; Ben-Dhaou, Cyrine; Ouimet, Tanja; Baudouin, Christophe; Wurm, Michel; Melik Parsadaniantz, Stéphane Less PAIN. 160(2):307-321, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Dual enkephalinase inhibitors are a promising topical medication for the safe and efficacious alleviation of corneal pain and inflammation.
Parental emotion and pain control behaviour when faced with child's pain: the emotion regulatory role of parental pain-related attention-set shifting and heart rate variability Vervoort, Tine; Karos, Kai; Johnson, Dan; More Vervoort, Tine; Karos, Kai; Johnson, Dan; Sütterlin, Stefan; Van Ryckeghem, Dimitri Less PAIN. 160(2):322-333, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Parental pain-related attention-set shifting and heart rate variability impacts parental distress and pain control behaviour when faced with their child's pain.
Dopamine receptor D2, but not D1, mediates descending dopaminergic pathway–produced analgesic effect in a trigeminal neuropathic pain mouse model Liu, Sufang; Tang, Yuanyuan; Shu, Hui; More Liu, Sufang; Tang, Yuanyuan; Shu, Hui; Tatum, Delton; Bai, Qian; Crawford, Joshua; Xing, Ying; Lobo, Mary Kay; Bellinger, Larry; Kramer, Phillip; Tao, Feng Less PAIN. 160(2):334-344, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: The descending A11-spinal trigeminal nucleus caudalis dopaminergic pathway–produced analgesic effect on trigeminal neuropathic pain is mediated by dopamine receptor D2, but not D1.
Acquisition of analgesic properties by the cholecystokinin (CCK)/CCK2 receptor system within the amygdala in a persistent inflammatory pain condition Roca-Lapirot, Olivier; Fossat, Pascal; Ma, Sherie; More Roca-Lapirot, Olivier; Fossat, Pascal; Ma, Sherie; Egron, Karine; Trigilio, Gabriella; López-González, María-José; Covita, João; Bouali-Benazzouz, Rabia; Favereaux, Alexandre; Gundlach, Andrew L.; Landry, Marc Less PAIN. 160(2):345-357, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: In inflammatory pain conditions, the CCK/CCK2 system of the central amygdala switches from an anxiogenic to an analgesic role that implicates descending control to the spinal cord.
Increased pain sensitivity and decreased opioid analgesia in T-cell-deficient mice and implications for sex differences Rosen, Sarah F.; Ham, Boram; Haichin, Michael; More Rosen, Sarah F.; Ham, Boram; Haichin, Michael; Walters, Ilana C.; Tohyama, Sarasa; Sotocinal, Susana G.; Mogil, Jeffrey S. Less PAIN. 160(2):358-366, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: We find T-cell-deficient mice to have increased baseline pain sensitivity, decreased morphine analgesia, and absent opioid-mediated stress-induced analgesia, all due to CD4+ T cells.
PRISM: a brief screening tool to identify risk in parents of youth with chronic pain Simons, Laura E.; Lewandowski Holley, Amy; Phelps, Emily; More Simons, Laura E.; Lewandowski Holley, Amy; Phelps, Emily; Wilson, Anna C. Less PAIN. 160(2):367-374, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Parent Risk Screening Measure is the first tool to identify level of risk associated with distress and maladaptive behaviors in parents of youth with pain.
Contribution of dorsal root ganglion octamer transcription factor 1 to neuropathic pain after peripheral nerve injury Yuan, Jingjing; Wen, Jing; Wu, Shaogen; More Yuan, Jingjing; Wen, Jing; Wu, Shaogen; Mao, Yuanyuan; Mo, Kai; Li, Zhisong; Su, Songxue; Gu, Hanwen; Ai, Yanqiu; Bekker, Alex; Zhang, Wei; Tao, Yuan-Xiang Less PAIN. 160(2):375-384, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Dorsal root ganglion octamer transcription factor 1 participates in neuropathic pain by transcriptionally activating Dnmt3a and subsequently epigenetic silencing of Oprm1 and Kcan2 in the dorsal root ganglion.
Divergent influences of the locus coeruleus on migraine pathophysiology Vila-Pueyo, Marta; Strother, Lauren C; Kefel, Malak; More Vila-Pueyo, Marta; Strother, Lauren C; Kefel, Malak; Goadsby, Peter J.; Holland, Philip R. Less PAIN. 160(2):385-394, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: Go to Full Text of this Article In Brief: In vivo, electrophysiology highlights a role for the locus coeruleus in trigeminal nociception and migraine aura, linking pain and dysfunctional arousal in migraine. Go to Full Text of this Article
Perceptions of gendered and ungendered pain relief norms and stereotypes using Q-methodology Wratten, Samantha; Eccleston, Christopher; Keogh, Edmund Wratten, Samantha; Eccleston, Christopher; Keogh, Edmund Less PAIN. 160(2):395-406, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Two Q-sort studies found that perceived analgesic efficacy and gender norm conformity determine social acceptability of male and female use of analgesic behaviours.
Children and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events Brandow, Amanda M.; Hansen, Karla; Nugent, Melodee; More Brandow, Amanda M.; Hansen, Karla; Nugent, Melodee; Pan, Amy; Panepinto, Julie A.; Stucky, Cheryl L. Less PAIN. 160(2):407-416, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: Go to Full Text of this Article In Brief: Quantitative sensory testing in patients with sickle cell disease prospectively shows increased cold and mechanical hypersensitivity during acute painful events as compared to baseline health. Go to Full Text of this Article
Incident opioid use and risk of hip fracture among persons with Alzheimer disease: a nationwide matched cohort study Taipale, Heidi; Hamina, Aleksi; Karttunen, Niina; More Taipale, Heidi; Hamina, Aleksi; Karttunen, Niina; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija Less PAIN. 160(2):417-423, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: Go to Full Text of this Article In Brief: New opioid use was associated with an increased risk of hip fracture and the risk increased with opioid strength, among persons with Alzheimer disease. Go to Full Text of this Article
The association between multiple sclerosis and pain medications Burkill, Sarah; Montgomery, Scott; Kockum, Ingrid; More Burkill, Sarah; Montgomery, Scott; Kockum, Ingrid; Piehl, Fredrik; Strid, Pernilla; Hillert, Jan; Alfredsson, Lars; Olsson, Tomas; Bahmanyar, Shahram Less PAIN. 160(2):424-432, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: The increased risk of pain in patients with multiple sclerosis is driven primarily by neuropathic pain, rather than by migraine or musculoskeletal pain.
Long-term outcomes of adolescents with juvenile-onset fibromyalgia into adulthood and impact of depressive symptoms on functioning over time Kashikar-Zuck, Susmita; Cunningham, Natoshia; Peugh, James; More Kashikar-Zuck, Susmita; Cunningham, Natoshia; Peugh, James; Black, William R.; Nelson, Sarah; Lynch-Jordan, Anne M.; Pfeiffer, Megan; Tran, Susan T.; Ting, Tracy V.; Arnold, Lesley M.; Carle, Adam; Noll, Jennie; Powers, Scott W.; Lovell, Daniel J. Less PAIN. 160(2):433-441, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Longitudinal trajectory analyses showed decreasing pain over time in juvenile-onset fibromyalgia. A worsening depressive symptom trajectory was associated with the poorest outcomes in adulthood.
Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn Dickie, Allen C.; Bell, Andrew M.; Iwagaki, Noboru; More Dickie, Allen C.; Bell, Andrew M.; Iwagaki, Noboru; Polgár, Erika; Gutierrez-Mecinas, Maria; Kelly, Rosalind; Lyon, Heather; Turnbull, Kirsten; West, Steven J.; Etlin, Alexander; Braz, Joao; Watanabe, Masahiko; Bennett, David L.H.; Basbaum, Allan I.; Riddell, John S.; Todd, Andrew J. Less PAIN. 160(2):442-462, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: Go to Full Text of this Article In Brief: Superficial dorsal horn excitatory interneuron populations, as identified by neuropeptide expression, differ in morphological, electrophysiological, and pharmacological properties. This has implications for understanding pain processing. Go to Full Text of this Article
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury Baskozos, Georgios; Dawes, John M.; Austin, Jean S.; More Baskozos, Georgios; Dawes, John M.; Austin, Jean S.; Antunes-Martins, Ana; McDermott, Lucy; Clark, Alex J.; Trendafilova, Teodora; Lees, Jon G.; McMahon, Stephen B.; Mogil, Jeffrey S.; Orengo, Christine; Bennett, David L. Less PAIN. 160(2):463-485, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: Go to Full Text of this Article In Brief: Novel and annotated LncRNAs showed marked transcriptional change during neuron differentiation and after nerve injury. Identified LncRNAs were antisense or adjacent to pain genes and ion channels. Go to Full Text of this Article
Mechanistic pain profiling as a tool to predict the efficacy of 3-week nonsteroidal anti-inflammatory drugs plus paracetamol in patients with painful knee osteoarthritis Petersen, Kristian Kjær; Olesen, Anne Estrup; Simonsen, Ole; More Petersen, Kristian Kjær; Olesen, Anne Estrup; Simonsen, Ole; Arendt-Nielsen, Lars Less PAIN. 160(2):486-492, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: This study found that facilitated temporal summation was associated with poor pain alleviation after 3-week treatment of nonsteroidal anti-inflammatory drugs and paracetamol.
Behavioural discrimination of noxious stimuli in infants is dependent on brain maturation Green, Gabrielle; Hartley, Caroline; Hoskin, Amy; More Green, Gabrielle; Hartley, Caroline; Hoskin, Amy; Duff, Eugene; Shriver, Adam; Wilkinson, Dominic; Adams, Eleri; Rogers, Richard; Moultrie, Fiona; Slater, Rebeccah Less PAIN. 160(2):493-500, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: Go to Full Text of this Article In Brief: Facial expression discrimination between noxious and innocuous stimuli in preterm infants emerges at approximately 33 weeks' gestation and relates to evoked brain activity maturation. Go to Full Text of this Article
What is the effect of alcohol consumption on the risk of chronic widespread pain? A Mendelian randomisation study using UK Biobank Beasley, Marcus; Freidin, Maxim B.; Basu, Neil; More Beasley, Marcus; Freidin, Maxim B.; Basu, Neil; Williams, Frances M.K.; Macfarlane, Gary J. Less PAIN. 160(2):501-507, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Despite the strong association of moderate alcohol consumption with lowered reporting of chronic widespread pain, Mendelian randomisation does not support a beneficial effect for alcohol.
Vti1b promotes TRPV1 sensitization during inflammatory pain Sondermann, Julia R.; Barry, Allison M.; Jahn, Olaf; More Sondermann, Julia R.; Barry, Allison M.; Jahn, Olaf; Michel, Niklas; Abdelaziz, Reham; Kügler, Sebastian; Gomez-Varela, David; Schmidt, Manuela Less PAIN. 160(2):508-527, February 2019. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Discovery of Vti1b as a novel modulator of TRPV1 during inflammatory pain. Application of functional proteomics to define novel and pain state-dependent binding partners of native TRPV1 in dorsal root ganglia.
