Evaluation of a polymer-coated nanoparticle cream formulation of resiniferatoxin for the treatment of painful diabetic peripheral neuropathy Baskaran, Padmamalini; Mohandass, Adithya; Gustafson, Noah; More Baskaran, Padmamalini; Mohandass, Adithya; Gustafson, Noah; Bennis, Jane; Louis, Somaja; Alexander, Brenda; Nemenov, Mikhail I.; Thyagarajan, Baskaran; Premkumar, Louis S. Less PAIN. 164(4):782-790, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A highly penetrable nanoparticle cream formulation of resiniferatoxin has been developed and demonstrated its effectiveness in small and large animal models of painful diabetic peripheral neuropathy. Buy SDC
Adjuvanted recombinant zoster vaccine decreases herpes zoster-associated pain and the use of pain medication across 3 randomized, placebo-controlled trials Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; More Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; Cunningham, Anthony L.; Amakrane, Mohamed; Sullivan, Keith M.; Dagnew, Alemnew F.; Curran, Desmond; Schuind, Anne Less PAIN. 164(4):741-748, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Recombinant zoster vaccine is efficacious in reducing herpes zoster incidence in at-risk populations and seems to decrease pain duration and need for pain medication in breakthrough herpes zoster cases. Go to Full Text of this Article Open SDC
Mirror peripheral neuropathy and unilateral chronic neuropathic pain: insights from asymmetric neurological patterns in leprosy Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; More Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; Frassetto, Mariana; Stump, Patrick R. N. A. G.; Trindade, Maria A. B.; Harnik, Simone; Oliveira, Rodrigo A.; Macarenco, Ricardo S. S.; Doppler, Kathrin; Üçeyler, Nurcan; Mello, Evandro S.; Sommer, Claudia; Teixeira, Manoel J.; Galhardoni, Ricardo; de Andrade, Daniel C. Less PAIN. 164(4):717-727, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Mirror limb assessment in the same individual with leprosy showed that neuropathic pain was associated with heat pain thresholds but not with skin innervation. Go to Full Text of this Article Free SDC
Estimating individualized treatment effects using a risk-modeling approach: an application to epidural steroid injections for lumbar spinal stenosis Liu, Pinyan; Wu, Yitao; Xiao, Ziyu; More Liu, Pinyan; Wu, Yitao; Xiao, Ziyu; Gold, Laura S.; Heagerty, Patrick J.; Annaswamy, Thiru; Friedly, Janna; Turner, Judith A.; Jarvik, Jeffrey G.; Suri, Pradeep Less PAIN. 164(4):811-819, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A “risk-modeling” approach was used in randomized controlled trials of back pain to examine heterogeneity of treatment effect guided by the Predictive Approaches to Treatment effect Heterogeneity Statement framework. Buy SDC
Perception threshold tracking: validating a novel method for assessing function of large and small sensory nerve fibers in diabetic peripheral neuropathy with and without pain Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; More Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; Hansen, Tine Maria; Arendt-Nielsen, Lars; Ejskjaer, Niels; Mørch, Carsten Dahl Less PAIN. 164(4):886-894, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Perception threshold tracking is a novel method suitable for differentiating diabetic polyneuropathies from controls and some painful diabetic polyneuropathies from nonpainful ones. Buy SDC
Consistent pattern between physical activity measures and chronic pain levels: the Tromsø Study 2015 to 2016 Fjeld, Mats Kirkeby; Årnes, Anders Pedersen; Engdahl, Bo; More Fjeld, Mats Kirkeby; Årnes, Anders Pedersen; Engdahl, Bo; Morseth, Bente; Hopstock, Laila Arnesdatter; Horsch, Alexander; Stubhaug, Audun; Strand, Bjørn Heine; Nielsen, Christopher Sivert; Steingrímsdóttir, Ólöf Anna Less PAIN. 164(4):838-847, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Applying extensive physical activity measurements, results suggest inverse dose–response relationship between physical activity and chronic pain, with stronger associations for those with more severe pain. Go to Full Text of this Article Open SDC
Unbiased analysis of the dorsal root ganglion after peripheral nerve injury: no neuronal loss, no gliosis, but satellite glial cell plasticity Schulte, Annemarie; Lohner, Hannah; Degenbeck, Johannes; More Schulte, Annemarie; Lohner, Hannah; Degenbeck, Johannes; Segebarth, Dennis; Rittner, Heike L.; Blum, Robert; Aue, Annemarie Less PAIN. 164(4):728-740, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Deep learning-based analysis of large-scale bioimages of the dorsal root ganglion after nerve injury reveals satellite glial cell plasticity but no loss of sensory neurons. Go to Full Text of this Article Open SDC
Noncoding rare variants in PANX3 are associated with chronic back pain Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; More Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; Williams, Frances M. K.; Suri, Pradeep; Aulchenko, Yurii S.; Axenovich, Tatiana I.; Tsepilov, Yakov A. Less PAIN. 164(4):864-869, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Association of PANX3 with chronic back pain discovered and replicated using gene-based association analysis and summary statistics obtained from the UK Biobank and FinnGen samples. Buy SDC
Noncoding rare variants in PANX3 are associated with chronic back pain Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; More Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; Williams, Frances M. K.; Suri, Pradeep; Aulchenko, Yurii S.; Axenovich, Tatiana I.; Tsepilov, Yakov A. Less PAIN. 164(4):864-869, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Association of PANX3 with chronic back pain discovered and replicated using gene-based association analysis and summary statistics obtained from the UK Biobank and FinnGen samples. Buy SDC
Intrinsic and synaptic properties of adult mouse spinoperiaqueductal gray neurons and the influence of neonatal tissue damage Li, Jie; Serafin, Elizabeth K.; Baccei, Mark L. Li, Jie; Serafin, Elizabeth K.; Baccei, Mark L. Less PAIN. 164(4):905-917, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: The intrinsic membrane properties and primary afferent synaptic inputs that govern the firing of adult lamina I spino-periaqueductal gray neurons are unaffected by neonatal tissue damage. Buy SDC
Association between prescribed opioid dose and risk of motor vehicle crashes Quinn, Patrick D.; Chang, Zheng; Pujol, Toyya A.; More Quinn, Patrick D.; Chang, Zheng; Pujol, Toyya A.; Bair, Matthew J.; Gibbons, Robert D.; Kroenke, Kurt; D'Onofrio, Brian M. Less PAIN. 164(4):e228-e236, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Among 772,404 prescription opioid recipients, motor vehicle crash risk was greater during opioid therapy periods, even those involving doses ≤60 morphine milligram equivalents per day. Buy SDC
Indifference or hypersensitivity? Solving the riddle of the pain profile in individuals with autism Hoffman, Tseela; Bar-Shalita, Tami; Granovsky, Yelena; More Hoffman, Tseela; Bar-Shalita, Tami; Granovsky, Yelena; Gal, Eynat; Kalingel-Levi, Merry; Dori, Yael; Buxbaum, Chen; Yarovinsky, Natalya; Weissman-Fogel, Irit Less PAIN. 164(4):791-803, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Individuals with autism show that a pronociceptive profile comprises facilitative state and less efficient inhibition of tonic pain attributed to disease severity and sensory modulating disturbances. Buy SDC
Evaluation of a polymer-coated nanoparticle cream formulation of resiniferatoxin for the treatment of painful diabetic peripheral neuropathy Baskaran, Padmamalini; Mohandass, Adithya; Gustafson, Noah; More Baskaran, Padmamalini; Mohandass, Adithya; Gustafson, Noah; Bennis, Jane; Louis, Somaja; Alexander, Brenda; Nemenov, Mikhail I.; Thyagarajan, Baskaran; Premkumar, Louis S. Less PAIN. 164(4):782-790, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A highly penetrable nanoparticle cream formulation of resiniferatoxin has been developed and demonstrated its effectiveness in small and large animal models of painful diabetic peripheral neuropathy. Buy SDC
Tolerability and efficacy of duloxetine for the prevention of persistent musculoskeletal pain after trauma and injury: a pilot three-group randomized controlled trial Beaudoin, Francesca L.; Gaither, Rachel; DeLomba, Weston C.; More Beaudoin, Francesca L.; Gaither, Rachel; DeLomba, Weston C.; McLean, Samuel A. Less PAIN. 164(4):855-863, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A randomized, double-blind, placebo-controlled clinical trial of duloxetine shows promise for the prevention of persistent posttraumatic pain when initiated in the acute period of injury. Buy
Delphi study to explore a new diagnosis for “ineffective” long-term opioid therapy for chronic pain Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; More Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; Van Cleve, Raymond; Black, Anne C.; Compton, Peggy; Becker, William C. Less PAIN. 164(4):870-876, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A Delphi study explored the creation of a new diagnostic entity, separate from opioid use disorder, to characterize problems that arise for some patients prescribed opioids. Buy SDC
Noncoding rare variants in PANX3 are associated with chronic back pain Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; More Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; Williams, Frances M. K.; Suri, Pradeep; Aulchenko, Yurii S.; Axenovich, Tatiana I.; Tsepilov, Yakov A. Less PAIN. 164(4):864-869, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Association of PANX3 with chronic back pain discovered and replicated using gene-based association analysis and summary statistics obtained from the UK Biobank and FinnGen samples. Buy SDC
Generalization of pain-related avoidance behavior based on de novo categorical knowledge Glogan, Eveliina; Gatzounis, Rena; Bennett, Marc Patrick; More Glogan, Eveliina; Gatzounis, Rena; Bennett, Marc Patrick; Holthausen, Katharina; Meulders, Ann Less PAIN. 164(4):895-904, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: In healthy participants, pain-associated movements were categorically associated with proprioceptively dissimilar pain-free movements, thus motivating unnecessary avoidance of the categorically associated, pain-free movements. Go to Full Text of this Article Open SDC
Evaluation of a polymer-coated nanoparticle cream formulation of resiniferatoxin for the treatment of painful diabetic peripheral neuropathy Baskaran, Padmamalini; Mohandass, Adithya; Gustafson, Noah; More Baskaran, Padmamalini; Mohandass, Adithya; Gustafson, Noah; Bennis, Jane; Louis, Somaja; Alexander, Brenda; Nemenov, Mikhail I.; Thyagarajan, Baskaran; Premkumar, Louis S. Less PAIN. 164(4):782-790, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A highly penetrable nanoparticle cream formulation of resiniferatoxin has been developed and demonstrated its effectiveness in small and large animal models of painful diabetic peripheral neuropathy. Buy SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Delphi study to explore a new diagnosis for “ineffective” long-term opioid therapy for chronic pain Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; More Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; Van Cleve, Raymond; Black, Anne C.; Compton, Peggy; Becker, William C. Less PAIN. 164(4):870-876, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A Delphi study explored the creation of a new diagnostic entity, separate from opioid use disorder, to characterize problems that arise for some patients prescribed opioids. Buy SDC
Unbiased analysis of the dorsal root ganglion after peripheral nerve injury: no neuronal loss, no gliosis, but satellite glial cell plasticity Schulte, Annemarie; Lohner, Hannah; Degenbeck, Johannes; More Schulte, Annemarie; Lohner, Hannah; Degenbeck, Johannes; Segebarth, Dennis; Rittner, Heike L.; Blum, Robert; Aue, Annemarie Less PAIN. 164(4):728-740, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Deep learning-based analysis of large-scale bioimages of the dorsal root ganglion after nerve injury reveals satellite glial cell plasticity but no loss of sensory neurons. Go to Full Text of this Article Open SDC
Healthy dietary indices and noncancer pain: a systematic review of cross-sectional and longitudinal studies Chand, Rani R.; Blyth, Fiona M.; Khalatbari-Soltani, Saman Chand, Rani R.; Blyth, Fiona M.; Khalatbari-Soltani, Saman Less PAIN. 164(4):e177-e189, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Free SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
A qualitative exploration of dentists' opioid prescribing decisions within U.S. veterans affairs facilities Sharp, Lisa K.; Solanki, Pooja; Boyer, Taylor; More Sharp, Lisa K.; Solanki, Pooja; Boyer, Taylor; Vivo, Amanda; Kale, Ibuola; Hughes, Ashley M.; Gibson, Gretchen; Jurasic, M. Marianne; Evans, Charlesnika T.; Suda, Katie J. Less PAIN. 164(4):749-757, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Qualitative interviews with dentists offered possible intervention targets to expand implementation of safe opioid prescribing for acute dental pain management within the Veterans Affairs. Go to Full Text of this Article Open SDC
Indifference or hypersensitivity? Solving the riddle of the pain profile in individuals with autism Hoffman, Tseela; Bar-Shalita, Tami; Granovsky, Yelena; More Hoffman, Tseela; Bar-Shalita, Tami; Granovsky, Yelena; Gal, Eynat; Kalingel-Levi, Merry; Dori, Yael; Buxbaum, Chen; Yarovinsky, Natalya; Weissman-Fogel, Irit Less PAIN. 164(4):791-803, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Individuals with autism show that a pronociceptive profile comprises facilitative state and less efficient inhibition of tonic pain attributed to disease severity and sensory modulating disturbances. Buy SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Microdosing psilocybin for chronic pain: a case series Lyes, Matthew; Yang, Kevin H.; Castellanos, Joel; More Lyes, Matthew; Yang, Kevin H.; Castellanos, Joel; Furnish, Timothy Less PAIN. 164(4):698-702, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Low-dose psilocybin, a psychedelic serotonergic agonist, may provide analgesic benefits to patients with chronic neuropathic pain with minimal physical or psychotropic side effects. Buy
Healthy dietary indices and noncancer pain: a systematic review of cross-sectional and longitudinal studies Chand, Rani R.; Blyth, Fiona M.; Khalatbari-Soltani, Saman Chand, Rani R.; Blyth, Fiona M.; Khalatbari-Soltani, Saman Less PAIN. 164(4):e177-e189, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Free SDC
Mild cognitive impairment and major depressive disorder as confounders in the study on association between chronic low back pain and brain atrophy Chang, Min Cheol Chang, Min Cheol Less PAIN. 164(4):e237, April 2023. Favorite PDF Permissions Buy
Association between prescribed opioid dose and risk of motor vehicle crashes Quinn, Patrick D.; Chang, Zheng; Pujol, Toyya A.; More Quinn, Patrick D.; Chang, Zheng; Pujol, Toyya A.; Bair, Matthew J.; Gibbons, Robert D.; Kroenke, Kurt; D'Onofrio, Brian M. Less PAIN. 164(4):e228-e236, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Among 772,404 prescription opioid recipients, motor vehicle crash risk was greater during opioid therapy periods, even those involving doses ≤60 morphine milligram equivalents per day. Buy SDC
No association of postoperative opioid usage with long-term surgery outcomes in patients with liver cancer: a population-based retrospective cohort study Yeh, Pin-Hung; Yeh, Han-Wei; Yang, Shun-Fa; More Yeh, Pin-Hung; Yeh, Han-Wei; Yang, Shun-Fa; Wang, Yu-Hsun; Chou, Ming-Chih; Tsai, Ping-Kun; Yeh, Chao-Bin Less PAIN. 164(4):848-854, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: In this 812-case retrospective cohort study, postoperative opioids do not affect overall survival and recurrence-free survival for hepatocellular carcinoma patient who underwent hepatectomy or liver transplantation. Buy SDC
A double-blind phase II randomized controlled trial of an online cognitive bias modification for interpretation program with and without psychoeducation for people with chronic pain Sharpe, Louise; Jones, Emma Blaisdale; Pradhan, Poorva; More Sharpe, Louise; Jones, Emma Blaisdale; Pradhan, Poorva; Todd, Jemma; Colagiuri, Ben Less PAIN. 164(4):e217-e227, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Cognitive bias modification of interpretation improved pain severity and pain interference compared with placebo. Psychoeducation did not improve the efficacy of cognitive bias modification of interpretation. Go to Full Text of this Article Free SDC
Delphi study to explore a new diagnosis for “ineffective” long-term opioid therapy for chronic pain Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; More Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; Van Cleve, Raymond; Black, Anne C.; Compton, Peggy; Becker, William C. Less PAIN. 164(4):870-876, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A Delphi study explored the creation of a new diagnostic entity, separate from opioid use disorder, to characterize problems that arise for some patients prescribed opioids. Buy SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Perception threshold tracking: validating a novel method for assessing function of large and small sensory nerve fibers in diabetic peripheral neuropathy with and without pain Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; More Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; Hansen, Tine Maria; Arendt-Nielsen, Lars; Ejskjaer, Niels; Mørch, Carsten Dahl Less PAIN. 164(4):886-894, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Perception threshold tracking is a novel method suitable for differentiating diabetic polyneuropathies from controls and some painful diabetic polyneuropathies from nonpainful ones. Buy SDC
Adjuvanted recombinant zoster vaccine decreases herpes zoster-associated pain and the use of pain medication across 3 randomized, placebo-controlled trials Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; More Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; Cunningham, Anthony L.; Amakrane, Mohamed; Sullivan, Keith M.; Dagnew, Alemnew F.; Curran, Desmond; Schuind, Anne Less PAIN. 164(4):741-748, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Recombinant zoster vaccine is efficacious in reducing herpes zoster incidence in at-risk populations and seems to decrease pain duration and need for pain medication in breakthrough herpes zoster cases. Go to Full Text of this Article Open SDC
Adjuvanted recombinant zoster vaccine decreases herpes zoster-associated pain and the use of pain medication across 3 randomized, placebo-controlled trials Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; More Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; Cunningham, Anthony L.; Amakrane, Mohamed; Sullivan, Keith M.; Dagnew, Alemnew F.; Curran, Desmond; Schuind, Anne Less PAIN. 164(4):741-748, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Recombinant zoster vaccine is efficacious in reducing herpes zoster incidence in at-risk populations and seems to decrease pain duration and need for pain medication in breakthrough herpes zoster cases. Go to Full Text of this Article Open SDC
Association between prescribed opioid dose and risk of motor vehicle crashes Quinn, Patrick D.; Chang, Zheng; Pujol, Toyya A.; More Quinn, Patrick D.; Chang, Zheng; Pujol, Toyya A.; Bair, Matthew J.; Gibbons, Robert D.; Kroenke, Kurt; D'Onofrio, Brian M. Less PAIN. 164(4):e228-e236, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Among 772,404 prescription opioid recipients, motor vehicle crash risk was greater during opioid therapy periods, even those involving doses ≤60 morphine milligram equivalents per day. Buy SDC
Adjuvanted recombinant zoster vaccine decreases herpes zoster-associated pain and the use of pain medication across 3 randomized, placebo-controlled trials Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; More Kim, Joon Hyung; Johnson, Robert; Kovac, Martina; Cunningham, Anthony L.; Amakrane, Mohamed; Sullivan, Keith M.; Dagnew, Alemnew F.; Curran, Desmond; Schuind, Anne Less PAIN. 164(4):741-748, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Recombinant zoster vaccine is efficacious in reducing herpes zoster incidence in at-risk populations and seems to decrease pain duration and need for pain medication in breakthrough herpes zoster cases. Go to Full Text of this Article Open SDC
Mirror peripheral neuropathy and unilateral chronic neuropathic pain: insights from asymmetric neurological patterns in leprosy Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; More Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; Frassetto, Mariana; Stump, Patrick R. N. A. G.; Trindade, Maria A. B.; Harnik, Simone; Oliveira, Rodrigo A.; Macarenco, Ricardo S. S.; Doppler, Kathrin; Üçeyler, Nurcan; Mello, Evandro S.; Sommer, Claudia; Teixeira, Manoel J.; Galhardoni, Ricardo; de Andrade, Daniel C. Less PAIN. 164(4):717-727, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Mirror limb assessment in the same individual with leprosy showed that neuropathic pain was associated with heat pain thresholds but not with skin innervation. Go to Full Text of this Article Free SDC
Unbiased analysis of the dorsal root ganglion after peripheral nerve injury: no neuronal loss, no gliosis, but satellite glial cell plasticity Schulte, Annemarie; Lohner, Hannah; Degenbeck, Johannes; More Schulte, Annemarie; Lohner, Hannah; Degenbeck, Johannes; Segebarth, Dennis; Rittner, Heike L.; Blum, Robert; Aue, Annemarie Less PAIN. 164(4):728-740, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Deep learning-based analysis of large-scale bioimages of the dorsal root ganglion after nerve injury reveals satellite glial cell plasticity but no loss of sensory neurons. Go to Full Text of this Article Open SDC
Tolerability and efficacy of duloxetine for the prevention of persistent musculoskeletal pain after trauma and injury: a pilot three-group randomized controlled trial Beaudoin, Francesca L.; Gaither, Rachel; DeLomba, Weston C.; More Beaudoin, Francesca L.; Gaither, Rachel; DeLomba, Weston C.; McLean, Samuel A. Less PAIN. 164(4):855-863, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A randomized, double-blind, placebo-controlled clinical trial of duloxetine shows promise for the prevention of persistent posttraumatic pain when initiated in the acute period of injury. Buy
Opioid dose and pain effects of an online pain self-management program to augment usual care in adults with chronic pain: a multisite randomized clinical trial Wilson, Marian; Dolor, Rowena J.; Lewis, Daniel; More Wilson, Marian; Dolor, Rowena J.; Lewis, Daniel; Regan, Saundra L.; Vonder Meulen, Mary Beth; Winhusen, T. John Less PAIN. 164(4):877-885, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Online pain self-management can augment usual care for adults with chronic pain. Benefits include opioid dose reductions that coincide with improved pain symptom management. Go to Full Text of this Article Open SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Patient preferences in the treatment of chronic musculoskeletal pain: a systematic review of discrete choice experiments Zhu, Mengting; Dong, Dong; Lo, Hermione Hin-Man; More Zhu, Mengting; Dong, Dong; Lo, Hermione Hin-Man; Wong, Samuel Yeung-Shan; Mo, Phoenix Kit-Han; Sit, Regina Wing-Shan Less PAIN. 164(4):675-689, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Mirror peripheral neuropathy and unilateral chronic neuropathic pain: insights from asymmetric neurological patterns in leprosy Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; More Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; Frassetto, Mariana; Stump, Patrick R. N. A. G.; Trindade, Maria A. B.; Harnik, Simone; Oliveira, Rodrigo A.; Macarenco, Ricardo S. S.; Doppler, Kathrin; Üçeyler, Nurcan; Mello, Evandro S.; Sommer, Claudia; Teixeira, Manoel J.; Galhardoni, Ricardo; de Andrade, Daniel C. Less PAIN. 164(4):717-727, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Mirror limb assessment in the same individual with leprosy showed that neuropathic pain was associated with heat pain thresholds but not with skin innervation. Go to Full Text of this Article Free SDC
Indifference or hypersensitivity? Solving the riddle of the pain profile in individuals with autism Hoffman, Tseela; Bar-Shalita, Tami; Granovsky, Yelena; More Hoffman, Tseela; Bar-Shalita, Tami; Granovsky, Yelena; Gal, Eynat; Kalingel-Levi, Merry; Dori, Yael; Buxbaum, Chen; Yarovinsky, Natalya; Weissman-Fogel, Irit Less PAIN. 164(4):791-803, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Individuals with autism show that a pronociceptive profile comprises facilitative state and less efficient inhibition of tonic pain attributed to disease severity and sensory modulating disturbances. Buy SDC
Stimulation of alpha-1 adrenoceptors may intensify cutaneous inflammation in complex regional pain syndrome Wijaya, Linda K.; Morici, Michael V.; Stumbles, Philip A.; More Wijaya, Linda K.; Morici, Michael V.; Stumbles, Philip A.; Finch, Philip M.; Drummond, Peter D. Less PAIN. 164(4):771-781, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Production of the proinflammatory cytokine interleukin-6 increased normally after in vitro stimulation of cutaneous α1 adrenoceptors in patients with complex regional pain syndrome. Buy
Auditory disturbances in patients with complex regional pain syndrome Drummond, Peter D.; Finch, Philip M. Drummond, Peter D.; Finch, Philip M. Less PAIN. 164(4):804-810, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Hyperacusis originates in the ipsilateral brainstem and midbrain rather than the peripheral auditory apparatus of patients with complex regional pain syndrome. Go to Full Text of this Article Free SDC
Recovery expectations can be assessed with single-item measures: findings of a systematic review and meta-analysis on the role of recovery expectations on return-to-work outcomes after musculoskeletal pain conditions Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; More Carrière, Junie S.; Donayre Pimentel, Stephania; Bou Saba, Sabine; Boehme, Blake; Berbiche, Djamal; Coutu, Marie-France; Durand, Marie-José Less PAIN. 164(4):e190-e206, April 2023. Abstract Abstract Favorite PDF Permissions Go to Full Text of this Article Open SDC
Reply to Monticone O'Connell, Neil Edward; Moore, R. Andrew; Stewart, Gavin; More O'Connell, Neil Edward; Moore, R. Andrew; Stewart, Gavin; Fisher, Emma; Hearn, Leslie; Eccleston, Christopher; Williams, Amanda C. de C. Less PAIN. 164(4):e239-e241, April 2023. Favorite PDF Permissions Buy
Delphi study to explore a new diagnosis for “ineffective” long-term opioid therapy for chronic pain Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; More Edmond, Sara N.; Snow, Jennifer L.; Pomeranz, Jamie; Van Cleve, Raymond; Black, Anne C.; Compton, Peggy; Becker, William C. Less PAIN. 164(4):870-876, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A Delphi study explored the creation of a new diagnostic entity, separate from opioid use disorder, to characterize problems that arise for some patients prescribed opioids. Buy SDC
Distinct and sex-specific expression of mu opioid receptors in anterior cingulate and somatosensory S1 cortical areas Zamfir, Maria; Sharif, Behrang; Locke, Samantha; More Zamfir, Maria; Sharif, Behrang; Locke, Samantha; Ehrlich, Aliza T.; Ochandarena, Nicole E.; Scherrer, Grégory; Ribeiro-da-Silva, Alfredo; Kieffer, Brigitte L.; Séguéla, Philippe Less PAIN. 164(4):703-716, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Pain-processing anterior cingulate and primary somatosensory cortical areas display distinct MOR expression profiles with prominent differences between output layers and sexes. Go to Full Text of this Article Open SDC
Perception threshold tracking: validating a novel method for assessing function of large and small sensory nerve fibers in diabetic peripheral neuropathy with and without pain Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; More Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; Hansen, Tine Maria; Arendt-Nielsen, Lars; Ejskjaer, Niels; Mørch, Carsten Dahl Less PAIN. 164(4):886-894, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Perception threshold tracking is a novel method suitable for differentiating diabetic polyneuropathies from controls and some painful diabetic polyneuropathies from nonpainful ones. Buy SDC
Consistent pattern between physical activity measures and chronic pain levels: the Tromsø Study 2015 to 2016 Fjeld, Mats Kirkeby; Årnes, Anders Pedersen; Engdahl, Bo; More Fjeld, Mats Kirkeby; Årnes, Anders Pedersen; Engdahl, Bo; Morseth, Bente; Hopstock, Laila Arnesdatter; Horsch, Alexander; Stubhaug, Audun; Strand, Bjørn Heine; Nielsen, Christopher Sivert; Steingrímsdóttir, Ólöf Anna Less PAIN. 164(4):838-847, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Applying extensive physical activity measurements, results suggest inverse dose–response relationship between physical activity and chronic pain, with stronger associations for those with more severe pain. Go to Full Text of this Article Open SDC
Spinal neurovascular coupling is preserved despite time-dependent alterations of spinal cord blood flow responses in a rat model of chronic back pain: implications for functional spinal cord imaging Paquette, Thierry; Eskandari, Nasim; Leblond, Hugues; More Paquette, Thierry; Eskandari, Nasim; Leblond, Hugues; Piché, Mathieu Less PAIN. 164(4):758-770, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Chronic pain does not alter spinal neurovascular coupling, which supports the use of spinal functional magnetic resonance imaging in animals and patients with chronic pain. Buy
A qualitative exploration of dentists' opioid prescribing decisions within U.S. veterans affairs facilities Sharp, Lisa K.; Solanki, Pooja; Boyer, Taylor; More Sharp, Lisa K.; Solanki, Pooja; Boyer, Taylor; Vivo, Amanda; Kale, Ibuola; Hughes, Ashley M.; Gibson, Gretchen; Jurasic, M. Marianne; Evans, Charlesnika T.; Suda, Katie J. Less PAIN. 164(4):749-757, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Qualitative interviews with dentists offered possible intervention targets to expand implementation of safe opioid prescribing for acute dental pain management within the Veterans Affairs. Go to Full Text of this Article Open SDC
A rose by another name? Characteristics that distinguish headache secondary to temporomandibular disorder from headache that is comorbid with temporomandibular disorder Sharma, Sonia; Slade, Gary D.; Fillingim, Roger B.; More Sharma, Sonia; Slade, Gary D.; Fillingim, Roger B.; Ohrbach, Richard Less PAIN. 164(4):820-830, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Coexistence of painful temporomandibular disorder and headache attributed to temporomandibular disorder increases the biopsychosocial burden of primary headache, highlighting the importance of comprehensive assessment and differential management. Buy SDC
Stimulation of alpha-1 adrenoceptors may intensify cutaneous inflammation in complex regional pain syndrome Wijaya, Linda K.; Morici, Michael V.; Stumbles, Philip A.; More Wijaya, Linda K.; Morici, Michael V.; Stumbles, Philip A.; Finch, Philip M.; Drummond, Peter D. Less PAIN. 164(4):771-781, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Production of the proinflammatory cytokine interleukin-6 increased normally after in vitro stimulation of cutaneous α1 adrenoceptors in patients with complex regional pain syndrome. Buy
Auditory disturbances in patients with complex regional pain syndrome Drummond, Peter D.; Finch, Philip M. Drummond, Peter D.; Finch, Philip M. Less PAIN. 164(4):804-810, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Hyperacusis originates in the ipsilateral brainstem and midbrain rather than the peripheral auditory apparatus of patients with complex regional pain syndrome. Go to Full Text of this Article Free SDC
Reply to Monticone O'Connell, Neil Edward; Moore, R. Andrew; Stewart, Gavin; More O'Connell, Neil Edward; Moore, R. Andrew; Stewart, Gavin; Fisher, Emma; Hearn, Leslie; Eccleston, Christopher; Williams, Amanda C. de C. Less PAIN. 164(4):e239-e241, April 2023. Favorite PDF Permissions Buy
Consistent pattern between physical activity measures and chronic pain levels: the Tromsø Study 2015 to 2016 Fjeld, Mats Kirkeby; Årnes, Anders Pedersen; Engdahl, Bo; More Fjeld, Mats Kirkeby; Årnes, Anders Pedersen; Engdahl, Bo; Morseth, Bente; Hopstock, Laila Arnesdatter; Horsch, Alexander; Stubhaug, Audun; Strand, Bjørn Heine; Nielsen, Christopher Sivert; Steingrímsdóttir, Ólöf Anna Less PAIN. 164(4):838-847, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Applying extensive physical activity measurements, results suggest inverse dose–response relationship between physical activity and chronic pain, with stronger associations for those with more severe pain. Go to Full Text of this Article Open SDC
Mirror peripheral neuropathy and unilateral chronic neuropathic pain: insights from asymmetric neurological patterns in leprosy Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; More Raicher, Irina; Zandonai, Alexandra P.; Anghinah, Isadora W.; Frassetto, Mariana; Stump, Patrick R. N. A. G.; Trindade, Maria A. B.; Harnik, Simone; Oliveira, Rodrigo A.; Macarenco, Ricardo S. S.; Doppler, Kathrin; Üçeyler, Nurcan; Mello, Evandro S.; Sommer, Claudia; Teixeira, Manoel J.; Galhardoni, Ricardo; de Andrade, Daniel C. Less PAIN. 164(4):717-727, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions Go to Full Text of this Article In Brief: Mirror limb assessment in the same individual with leprosy showed that neuropathic pain was associated with heat pain thresholds but not with skin innervation. Go to Full Text of this Article Free SDC
Pain interference in young adulthood and work participation Pooleri, Anand; Yeduri, Rishita; Horne, Gabrielle; More Pooleri, Anand; Yeduri, Rishita; Horne, Gabrielle; Frech, Adrianne; Tumin, Dmitry Less PAIN. 164(4):831-837, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Pain interference reported at age 29 predicted increased hazard of subsequent labor force exit and health-related work limitation in a nationally representative longitudinal study. Buy SDC
Noncoding rare variants in PANX3 are associated with chronic back pain Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; More Belonogova, Nadezhda M.; Kirichenko, Anatoly V.; Freidin, Maxim B.; Williams, Frances M. K.; Suri, Pradeep; Aulchenko, Yurii S.; Axenovich, Tatiana I.; Tsepilov, Yakov A. Less PAIN. 164(4):864-869, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Association of PANX3 with chronic back pain discovered and replicated using gene-based association analysis and summary statistics obtained from the UK Biobank and FinnGen samples. Buy SDC
Estimating individualized treatment effects using a risk-modeling approach: an application to epidural steroid injections for lumbar spinal stenosis Liu, Pinyan; Wu, Yitao; Xiao, Ziyu; More Liu, Pinyan; Wu, Yitao; Xiao, Ziyu; Gold, Laura S.; Heagerty, Patrick J.; Annaswamy, Thiru; Friedly, Janna; Turner, Judith A.; Jarvik, Jeffrey G.; Suri, Pradeep Less PAIN. 164(4):811-819, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: A “risk-modeling” approach was used in randomized controlled trials of back pain to examine heterogeneity of treatment effect guided by the Predictive Approaches to Treatment effect Heterogeneity Statement framework. Buy SDC
Perception threshold tracking: validating a novel method for assessing function of large and small sensory nerve fibers in diabetic peripheral neuropathy with and without pain Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; More Røikjer, Johan; Croosu, Suganthiya Santhiapillai; Frøkjær, Jens Brøndum; Hansen, Tine Maria; Arendt-Nielsen, Lars; Ejskjaer, Niels; Mørch, Carsten Dahl Less PAIN. 164(4):886-894, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Perception threshold tracking is a novel method suitable for differentiating diabetic polyneuropathies from controls and some painful diabetic polyneuropathies from nonpainful ones. Buy SDC
Microdosing psilocybin for chronic pain: a case series Lyes, Matthew; Yang, Kevin H.; Castellanos, Joel; More Lyes, Matthew; Yang, Kevin H.; Castellanos, Joel; Furnish, Timothy Less PAIN. 164(4):698-702, April 2023. Abstract Abstract In Brief In Brief Favorite PDF Permissions In Brief: Low-dose psilocybin, a psychedelic serotonergic agonist, may provide analgesic benefits to patients with chronic neuropathic pain with minimal physical or psychotropic side effects. Buy
Tolerability and efficacy of duloxetine for the prevention of persistent musculoskeletal pain after trauma and injury: a pilot three-group randomized controlled trial Beaudoin, Francesca L
