Basic section: PDF OnlyThe role of conditioning and verbal expectancy in the placebo responseVoudouris, Nicholas J.∗,a; Peck, Connie L.b; Coleman, GrahamebAuthor Information aDepartment of Psychology, Plenty Hospital, Mont Park, VictoriaAustralia bDepartment of Psychology, La Trobe University, Bundoora, VictoriaAustralia ∗Correspondence to: Dr. N.J. Voudouris, Dept. of Psychology, Plenty Hospital, Mont Park, Victoria, Australia. Submitted August 23, 1989; revised April 5, 1990; accepted May 1, 1990. Pain: October 1990 - Volume 43 - Issue 1 - p 121-128 doi: 10.1016/0304-3959(90)90057-K Buy Metrics Abstract Both conditioning and expectancy models have been offered in recent years as explanations for the placebo response. Following our earlier work on conditioning placebo responses in human subjects the current study examined the relative contribution made by conditioning and verbal expectancy. Group 1 received a Combined Expectancy and Conditioning Manipulation; group 2 received Expectancy Alone; group 3, Conditioning Alone; and group 4 was the control group. Subjects' responses were compared with and without a placebo cream, using iontophoretic pain stimulation. The results suggest that conditioning was more powerful than verbal expectancy in creating a placebo response. © Lippincott-Raven Publishers.