The animal model for chronic pain following sciatic nerve section in the rat has been studied varying the sensory afferents prior to nerve section, using the anaesthetic blocking of the sciatic nerve. The experimental parameters used were the day of onset of autotomy and the time course of autotomy. The results show that the anaesthetic blocking prior to nerve section significantly reduces the degree of autotomy.
Department of Neurosurgery, Faculty of Medicine, University of Cádiz, 11002, CádizSpain
*Correspondence address: José M. González-Darder, Department of Neurosurgery, Faculty of Medicine, 11002 Cádiz, Spain.
Submitted March 19, 1985; accepted June 21, 1985.