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Devor Marshall; Govrin-Lippmann, Ruth
PAIN: May 1983
doi: 10.1016/0304-3959(83)90087-8
Research report: PDF Only

Abstract AbstractAfferent fibers ending in nerve end neuromas in rats generate a substantial ectopic discharge and are sensitive to light pressure and to circulating adrenaline. Treatment of the nerve with colchicine or vinblastine at the time of the nerve section resulted in a dose-dependent reduction in the extent of this discharge. Such treatment also reduced neuroma discharge that had already gotten underway.

(Received 26 May 1982, accepted 7 September 1982)

© Lippincott-Raven Publishers.

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