To ascertain the effect of cochlear implantation (CI) on tinnitus and quality of life.
PubMed, Scopus, Web of Science, and Cochrane Library were searched through August 21, 2020. Search strategies used a combination of subject headings (e.g., MeSH in PubMed) and keywords for the following two concepts: cochlear implantation and tinnitus.
English articles reporting on pre-intervention tinnitus-related patient-reported outcome measures (e.g., Tinnitus Handicap Inventory [THI], Tinnitus Questionnaire [TQ], Visual Analogue Scale [VAS] for loudness) and quality of life measures (e.g., Nijmegen Cochlear Implantation Questionnaire [NCIQ] and Hospital Anxiety and Depression Scale [HADS]) for CI recipients were included.
Demographics, baseline, and follow-up data.
Total of 27 articles reporting on 1,285 patients (mean age 54.5 years, range 14–81) were included. Meta-analysis of all tinnitus-related measures demonstrated improvement following implantation, with a mean difference of −23.2 [95% CI: −28.8 to –17.7], –12.6 [95% CI: −17.5 to –7.8], and –4.5 [95% CI: −5.5 to –3.4] (p < 0.05 for all) for THI, TQ, and VAS, respectively. NCIQ increased by 12.2 points [95% CI: 8.2–16.2] (p < 0.05), indicating improved quality of life among CI recipients. Psychological comorbidities were also ameliorated, as evidenced by reductions in HADS depression (−1.7 [95% CI: −2.4 to −0.9]) and anxiety (−1.3 [95% CI: −2.1 to −0.5]) (p < 0.05 for both) scores.
Following CI, patients reported significant improvement in tinnitus via several validated questionnaires. Additional benefits include improved quality of life and reduction in psychological comorbidities.