To determine the prevalence of radiographic cochlear–facial nerve dehiscence (CFD).
Retrospective radiological study.
Two tertiary-referral centers.
Two hundred six temporal-bone computed tomography (CT) scans (405 total ears) of otology/neurotology patients from two academic institutions between the years 2014 and 2017.
The cochlear–facial nerve partition width (CFPW) was measured on coronal CT sections and defined as the shortest distance between the cochlear basal turn and facial nerve (FN) labyrinthine segment. We used logistics regression analyses to determine positive predictors for radiographic evidence of CFD.
The overall prevalence of radiographic CFD was 5.4% (22/406 ears). 9.2% of patients (19/206) had CFD. Of these 19 patients, only one patient had mixed hearing loss that could not be explained by any other vestibular or auditory etiology. Three out of 206 patients had dehiscence in both ears (1.4%). The average CFPW was 0.6 ± 0.2 mm, and fallopian canal width was 1.1 ± 0.02 mm (n = 405). Older age, use of traditional CT scans, and thinner CT slice thickness were significant predictors for radiographic CFD.
The radiographic prevalence of CFD is higher than what is reported in histologic studies, and may over-estimate the true prevalence of CFD. The clinician should keep this in mind when considering this as potential cause for third-window symptoms.
*Division of Otology & Neurotology, Department of Otolaryngology–Head and Neck Surgery, Stanford University School of Medicine, Stanford, California
†Division of Otolaryngology–Head and Neck Surgery, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts
Address correspondence and reprint requests to Nikolas H. Blevins, MD, Division of Otology & Neurotology, Department of Otolaryngology–Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Road, 2nd Floor, Stanford, CA 94305; E-mail: firstname.lastname@example.org
This work was supported by a National Institutes of Health National Center for Advancing Translational Science Clinical and Translational Science Award (UL1TR001085). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
The authors disclose no conflicts of interest.
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