To describe a successful paradigm for the treatment of large acoustic neuromas (vestibular schwannomas).
Retrospective case review.
Tertiary referral center.
The charts of 2,875 acoustic neuroma patients at Michigan Ear Institute were reviewed to identify 153 patients who underwent surgical resection for large acoustic neuromas (≥3 cm) between 2000 and 2009.
Staged surgical resection or single stage surgery with or without adjuvant stereotactic radiosurgery
Main Outcome Measure(s)
Postoperative facial nerve
outcomes are reported using the House-Brackmann (HB) facial nerve
grading scale and compared with historical controls from a literature review. Rates of adverse outcomes are also reported.
Seventy-five patients underwent staged surgical resection of their tumors, whereas 78 patients underwent either single stage surgery or surgery with subsequent stereotactic radiosurgery
. Eighty-one percent of patients in the staged surgical resection group had a postoperative HB Grade I or II facial nerve
function compared with 75% in the single stage surgical group. Overall, 78% of patients in the current study had HB Grade I or II after treatment compared with a mean of 53% in the literature for similar sized tumors. Our methods including the decision to use staged surgery
when necessary, dissection of tumor with stimulating dissector-directed intraoperative monitoring, and use of adjuvant stereotactic radiosurgery
Using the described paradigm, large acoustic neuromas can be successfully treated with either staged or single-stage surgical resection with or without adjuvant radiosurgery to obtain more favorable facial nerve
outcomes than historically reported controls while minimizing morbidity for the patient.