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Electric Charge Requirements of Pediatric Cochlear Implant Recipients Enrolled in the Childhood Development After Cochlear Implantation Study

Zwolan, Teresa A.*; O'Sullivan, Mary Beth*; Fink, Nancy E.; Niparko, John K.The CDACI Investigative Team

doi: 10.1097/MAO.0b013e318161aac7
Original Articles

Objective: To evaluate mapping characteristics of children with cochlear implants who are enrolled in the Childhood Development After Cochlear Implantation (CDACI) multicenter study.

Study Design: Longitudinal evaluation during 24 months of speech processor maps of children with cochlear implants prospectively enrolled in the study.

Setting: Six tertiary referral centers.

Subjects: One hundred eighty-eight children enrolled in the CDACI study who were 5 years old or younger at the time of enrollment. Of these children, 184 received unilateral implants, and 4 received simultaneous bilateral implants.

Intervention: Children attended regular mapping sessions at their implant clinic as part of the study protocol. Maps were examined for each subject at 4 different time intervals: at device activation and 6, 12, and 24 months postactivation.

Main Outcome Measures: Mean C/M levels (in charge per phase) were compared for 4 different time intervals, for 3 different devices, for 6 different implant centers, and for children with normal and abnormal cochleae.

Results: All 3 types of implant devices demonstrate significant increases in C/M levels between device activation and the 24-month appointment. Significant differences in mean C/M levels were noted between devices. Children with cochlear anomalies demonstrate significantly greater C/M levels than children with normal cochleae.

Conclusion: The CDACI study has enabled us to evaluate the mapping characteristics of pediatric patients who use 3 different devices and were implanted at a variety of implant centers. Analysis of such data enables us to better understand the mapping characteristics of children with cochlear implants.

*Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan; †Welch Center for Prevention, Epidemiology, and Clinical Research, Bloomberg School of Public Health; and ‡Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, U.S.A.

Address correspondence and reprint requests to Teresa A. Zwolan, Ph.D., Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI; E-mail:

The CDACI was supported by Grant R0l DC004797 from the National Institute On Deafness And Other Communication Disorders.

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute On Deafness And Other Communication Disorders or the National Institutes of Health.

Members of the CDACI Investigative Team include 1) House Ear Institute: Laurie Eisenberg, William Luxford, Karen Johnson, Amy Martinez, Jean DesJardin, Leslie Visser-Dumont, Sophie Ambrose, Carren Stika, and Melinda Gillinger; 2) Johns Hopkins Medical Center: John Niparko, Jill Chinnici, Howard Francis, Steve Bowditch, Jennifer Yeagle, Courtney Carver, Andrea Marlowe, Andrea Gregg, Jennifer Gross, and Rick Ostrander; 3) The River School: Nancy Mellon, Jennifer Mertes, and Mary O'Leary Kane; 4) University of Miami Medical Center: Annelle Hodges, Thomas Balkany, Alina Lopez, and Leslie Goodwin; 5) University of Michigan: Teresa Zwolan, Mary Beth O'Sullivan, Anita Vereb, and Caroline Arnedt; 6) University of North Carolina: Holly F. B. Teagle, Carolyn J. Brown, Craig A. Buchman, Carlton Zdanski, and Hannah Eskridge; 7) University of Texas at Dallas: Emily Tobey, Andrea Warner-Czyz, Deborah Rekart, Carol Cokely, Nicole Weissner, and Angela Boyd; 8) University of Miami Department of Psychology: Alexandra Quittner, Ivette Cruz, and David Barker; 9) Johns Hopkins University Data Coordinating Center: Nancy Fink, Nae-Yuh Wang, Daniel Habtemariam, Thelma Vilche, and Patricia Bayton.

© 2008 Otology & Neurotology, Inc.