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Intratympanic Corticosteroids for Sudden Idiopathic Sensorineural Hearing Loss

Banerjee, Avik; Parnes, Lorne S

doi: 10.1097/01.mao.0000185052.07513.5a
Sudden Sensorineural Hearing Loss
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Objective: To determine whether instillation of intratympanic steroids is effective in the treatment of sudden idiopathic sensorineural hearing loss.

Methods: A retrospective chart review of all patients who underwent intratympanic steroid treatment (methylprednisolone and/or dexamethasone) between 1996 and 2002 at a tertiary care university otology clinic. Thirty-three patients were identified, of which 26 met inclusion criteria for having an idiopathic hearing loss. Pretreatment and posttreatment pure-tone audiograms and speech discrimination scores were compared.

Results: Overall, there was a 27.2 ± 5.7dB improvement in the pure-tone thresholds and a 25.4 ± 6.2% improvement in speech discrimination scores. Those treated within 10 days of onset had a statistically significant better outcome than those treated after 10 days. No adverse reactions or complications were reported.

Conclusion: Instillation of intratympanic steroids represents a safe and potentially effective treatment of sudden idiopathic sensorineural hearing loss.

Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada

Address correspondence and reprint requests to Lorne S. Parnes, M.D., Department of Otolaryngology, University of Western Ontario, 339 Windermere Road, Room 6OF15, London, Ontario N6A 5A5, Canada; E-mail: parnes@uwo.ca

© 2005 Otology & Neurotology, Inc.