An Absence of TinnitusLowry, Louis D.*; Eisenman, Leonard M.†; Saunders, James C.‡Otology & Neurotology: July 2004 - Volume 25 - Issue 4 - p 474-478 Tinnitus Abstract Author Information We present and discuss a case of lifelong tinnitus in an otolaryngologist (L.D.L.) followed by complete elimination of the tinnitus as a result of a cerebral vascular accident located in the left corona radiata. Pre- and post-CVA audiograms showed no change in hearing. A magnetic resonance imaging study of the brain documents the size and location of the lesion. Discussion looks at recent studies of the central nervous system showing evidence of increased activity related to tinnitus. Our assessment of the lesion and the resulting loss of tinnitus can be explained by the neurophysiological model of tinnitus, which includes plasticity of the central nervous system. *Departments of Otolaryngology/Head and Neck Surgery and †Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania; and ‡Department of Otorhinolaryngology/Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A. Address correspondence and reprint requests to Dr. Louis D. Lowry, Department of Otolaryngology/Head and Neck Surgery, Thomas Jefferson University, 925 Chestnut Street, 6th Floor, Philadelphia, PA 19107; Email: email@example.com © 2004 Otology & Neurotology, Inc.