Uveitis: Fundamentals and Clinical Practice, 3rd Edition.
Robert B. Nussenblatt and Scott M. Whitcup. St. Louis: Mosby, Inc., 2003. Pages: 428. Price: $125.00. ISBN 0-3230-2237-5.
Uveitis: Fundamentals and Clinical Practice, third edition, is an excellent comprehensive text covering everything a practitioner needs to know about uveitis. The book is organized in a logical and well thought out sequence, with 244 illustrations and 77 color plates.
The text is divided into five parts with 29 chapters. In Part I, the authors detail elements of the immune system and discuss essential immune mechanisms involved with intraocular inflammatory disease. Part II evaluates diagnostic methods of ocular inflammation. Chapters in this section include medical history of a patient with uveitis (with a sample uveitis questionnaire), examination of a patient with uveitis, development of a differential diagnosis, diagnostic testing, and evaluation of the uveitis literature. Medical therapy and surgical intervention is described in Part III. The authors discuss indications, dosage, and effects of corticosteroids, cytotoxic agents, cyclosporins, and antivirals as well as the role of surgery in patients with uveitis. Part IV thoroughly covers infectious uveitic conditions and includes chapters about bacterial and fungal diseases, and Acquired Immunodeficiency Syndrome and other viral diseases. Part V, with a layout similar to that of Part IV, evaluates noninfectious uveitic conditions such as anterior uveitis, sarcoidosis, and retinal vasculitis, and contains a new chapter for this most recent edition on scleritis.
As an optometry student, the first author (ML) found Part I to be a thorough and helpful review of the immune system with relationship to the eye, but we are not so sure that a practitioner would benefit as much from this part. Parts II and III are more clinically focused and give a complete account of uveitis from clinical presentation to differential diagnosis and treatment options. We are most excited about Parts IV and V. For each specific disease the etiology, epidemiology, clinical and ocular manifestations, diagnosis, and a detailed treatment are described. We found these sections to be very helpful and easy to use as a reference. We particularly enjoyed the end of each chapter, where cases are presented along with a therapy approach.
Compared to the second edition, great improvements have been made to the text. Color plates have been added, which are more beneficial for diagnosing. Some of the tables and charts have been redesigned for easier interpretation. Most importantly, updated and new information on uveitis has been incorporated into this new edition. Specifically, in the chapter on Acquired Immunodeficiency Syndrome a new section has been dedicated to the use of highly active antiviral therapy to treat cytomegalovirus retinitis. Also, new sections on pharmeceutical agents like infliximab, etanercept, and famciclovir have been added for completeness of current treatments.
Uveitis; Fundamentals and Clinical Practice is an absolutely exceptional reference. In fact, it is difficult to find anything negative about the book. The authors, leading experts on uveitis, do an excellent job of presenting the material in an organized way, with great color plates and illustrations to supplement the text. We recommend Uveitis to every student and physician in eye care as a must-have reference book.
Mary Ellen Luebbers
Michael J. Giese
The Ohio State University College of Optometry