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Validation of a Clinical Aberrometer Using Pyramidal Wavefront Sensing

Singh, Neeraj K. BSOptom, MPhil1*; Jaskulski, Matt PhD1; Ramasubramanian, Viswanathan BSOptom, PhD1; Meyer, Dawn OD1; Reed, Olivia OD, MS1; Rickert, Martin E. PhD1; Bradley, Arthur PhD1; Kollbaum, Pete S. OD, PhD1

doi: 10.1097/OPX.0000000000001435

SIGNIFICANCE Measurement of ocular aberrations is a critical component of many optical corrections.

PURPOSE This study examines the accuracy and repeatability of a newly available high-resolution pyramidal wavefront sensor–based aberrometer (Osiris by Costruzione Strumenti Oftalmici, Firenze, Italy).

METHODS An engineered model eye and a dilated presbyopic eye were used to assess accuracy and repeatability of aberration measurements after systematic introduction of lower- and higher-order aberrations with calibrated trial lenses (sphere +10.00 to −10.00 D, and astigmatic −4.00 and −2.00 D with axis 180, 90, and 45°) and phase plates (−0.57 to 0.60 μm of Seidel spherical aberration defined over a 6-mm pupil diameter). Osiris aberration measurements were compared with those acquired on a previously calibrated COAS-HD aberrometer for foveal and peripheral optics both with and without multizone dual-focus contact lenses. The impact of simulated axial and lateral misalignment was evaluated.

RESULTS Root-mean-square errors for paraxial sphere (corneal plane), cylinder, and axis were, respectively, 0.07, 0.11 D, and 1.8° for the engineered model and 0.15, 0.26 D, and 2.7° for the presbyopic eye. Repeatability estimates (i.e., standard deviation of 10 repeat measures) for the model and presbyopic eyes were 0.026 and 0.039 D for spherical error. Root-mean-square errors of 0.01 and 0.02 μm, respectively, were observed for primary spherical aberration and horizontal coma (model eye). Foveal and peripheral measures of higher- and lower-order aberrations measured with the Osiris closely matched parallel data collected with the COAS-HD aberrometer both with and without dual-focus zonal bifocal contact lenses. Operator errors of focus and alignment introduced changes of 0.018 and 0.02 D/mm in sphere estimates.

CONCLUSIONS The newly available clinical pyramidal aberrometer provided accurate and repeatable measures of lower- and higher-order aberrations, even in the challenging but clinically important cases of peripheral retina and multifocal optics.

1School of Optometry, Indiana University, Bloomington, Indiana


Submitted: March 19, 2019

Accepted: June 17, 2019

Funding/Support: CooperVision, CA (to PSK and AB).

Conflict of Interest Disclosure: None of the authors have reported a conflict of interest.

Author Contributions: Conceptualization: AB, PSK; Data Curation: NKS; Formal Analysis: NKS, MJ, MR; Funding Acquisition: PSK; Investigation: NKS, VR, DM, OR, AB, PSK; Methodology: NKS, AB, PSK; Project Administration: PSK; Software: NKS, MJ; Supervision: AB, PSK; Validation: NKS; Visualization: AB, PSK; Writing – Original Draft: NKS; Writing – Review & Editing: NKS, MJ, VR, DM, OR, MR, AB, PSK.

© 2019 American Academy of Optometry