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Assessing the Validity of Measurements of Swept-source and Partial Coherence Interferometry Devices in Cataract Patients

Ghaffari, Reza MD1; Mahmoudzadeh, Raziyeh MD1; Mohammadi, S.Saeed MD1; Salabati, Mirataollah MD1; Latifi, Golshan MD1*; Ghassemi, Hamed MD1

doi: 10.1097/OPX.0000000000001433
ORIGINAL INVESTIGATION
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SIGNIFICANCE The validity of measurements of OA-2000 (Tomey, Nagoya, Japan), a new swept-source optical coherence tomography–based biometer, was evaluated in comparison with IOLMaster 500 (Carl Zeiss Meditec AG, Jena, Germany) as a reference method for optical biometry in cataract patients.

PURPOSE This article compares the validity of measurements between OA-2000 and IOLMaster 500.

METHODS In this cross-sectional study, axial length, lens thickness, anterior chamber depth, and keratometry readings were obtained by the OA-2000 and IOLMaster 500. Two measurements were taken by each method. Patients in which any one of the biometry methods could not be performed owing to severity of the cataract were excluded from the study. Repeatability of measurements was presented by coefficient of variation, and Bland-Altman method was used for evaluating the agreement between the two biometers.

RESULTS Fifty-eight eyes of 58 cataract patients with mean ± standard deviation age of 61.4 ± 8.3 years were included in this study. Intraclass correlation ranged from 0.898 to 0.901 and showed good to excellent reliability. It was good for keratometry 1 (0.898) and excellent for keratometry 2 (0.992), axial length (0.999), and anterior chamber depth (0.901). Bland-Altman analysis showed good agreement between the swept-source optical coherence tomography and partial coherence interferometry devices for axial length, anterior chamber depth, and mean keratometry, with narrow 95% limits of agreement (−0.09 to 0.1 mm, −0.33 to 0.54 mm, −0.97 to 1.03 D, respectively), and also indicated small mean difference (0.01 for axial length, 0.11 for anterior chamber depth, 0.03 for mean keratometry, respectively) for all comparisons.

CONCLUSIONS OA-2000 as a new swept-source optical coherence tomography has an excellent repeatability for measurement of biometric data in cataract patients, comparing with the standard partial coherence interferometry biometer (IOLMaster 500).

1Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

*golshan24@yahoo.com

Submitted: February 12, 2019

Accepted: June 12, 2019

Funding/Support: None of the authors have reported funding/support.

Conflict of Interest Disclosure: None of the authors have reported a conflict of interest. The authors were responsible for preparation of this article and the decision to submit this article for publication. Each of the authors had full access to the study data and take full responsibility for their presentation in this article.

Study Registration Information: Original study registered in Tehran University of Medical Sciences.

Author Contributions: Conceptualization: RG, GL, HG; Data Curation: RG, RM, MS, GL, HG; Formal Analysis: RM, MS; Investigation: GL; Methodology: RG, GL; Project Administration: SSM, MS, GL; Resources: RG; Software: HG; Supervision: SSM, GL, HG; Validation: RG, MS, GL; Visualization: RG, GL; Writing – Original Draft: RM, GL; Writing – Review & Editing: SSM, GL.

© 2019 American Academy of Optometry