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Comparison of Three Gaze-position Calibration Techniques in First Purkinje Image–based Eye Trackers

Ntodie, Michael PhD, MSc, OD1; Bharadwaj, Shrikant R. PhD, BSOpt2,3; Balaji, Swaathi BSOpt2; Saunders, Kathryn J. PhD1; Little, Julie-Anne PhD, MCOptom1*

doi: 10.1097/OPX.0000000000001405

SIGNIFICANCE This study highlights potential differences that can arise in gaze-position estimates from first Purkinje image–based eye trackers based on how individual Hirschberg ratios (HRs) are calculated.

PURPOSE The purpose of this study was to evaluate the accuracy and repeatability of eccentric-viewing, prism-based, and theoretical techniques that are routinely used to calibrate HR in first Purkinje image–based eye trackers.

METHODS Hirschberg ratios of 28 participants (18 to 40 years old) were obtained using the PlusOptix PowerRef 3 photorefractor and eye tracker. In the gold standard eccentric-viewing technique, participants viewed eccentric targets (±12°, 4° steps) at 2 m. In the prism-based technique, 4 to 16Δ-D base-out and base-in prisms were placed in 4Δ-D steps before an eye occluded with an infrared filter; the fellow eye fixated a target at 1 m. Each participant's HR was calculated as the slope of the linear regression of the shift in Purkinje image relative to the pupil center for each target eccentricity or induced prism power. Theoretical HR was calculated from the participant's corneal curvature and anterior chamber depth measures. Data collection was repeated on another visit using all three techniques to assess repeatability. Data were also obtained from an Indian cohort (n = 30, 18 to 40 years old) using similar protocols.

RESULTS Hirschberg ratio ranged from 10.61 to 14.63°/mm (median, 11.90°/mm) in the eccentric-viewing technique. The prism-based and theoretical techniques demonstrated inaccuracies of 12 and 4% relative to the eccentric-viewing technique. The 95% limits of agreement of intrasubject variability were ±2.00, ±0.40, and ±0.30°/mm for the prism-based, eccentric-viewing, and theoretical techniques, respectively (P > .05). Intraclass correlation coefficients (95% confidence interval) were 0.99 (0.98 to 1.00) for eccentric, 0.99 (0.99 to 1.00) for theoretical, and 0.88 (0.74 to 0.94) for prism-based techniques. Similar results were found for the Indian cohort.

CONCLUSIONS The prism-based and theoretical techniques both demonstrated relative inaccuracies in measures of HR compared with the eccentric-viewing technique. The prism-based technique exhibited the poorest repeatability.

1Optometry and Vision Science Research Group, Biomedical Sciences Research Institute, Ulster University, Coleraine, United Kingdom

2Prof. Brien Holden Eye Research Centre, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India

3Bausch & Lomb School of Optometry, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India


Submitted: August 27, 2017

Accepted: April 2, 2019

Funding/Support: The Vice Chancellor's Research Scholarship, Ulster University, Coleraine, United Kingdom (to MN) and Fast Track for Young Scientist grant (to SRB).

Conflict of Interest Disclosure: None of the authors have reported a financial conflict of interest.

Author Contributions and Acknowledgments: Conceptualization: SRB, KJS, J-AL; Data Curation: MN, J-AL; Formal Analysis: J-AL; Funding Acquisition: SRB, J-AL; Investigation: MN, SRB, SB, J-AL; Methodology: MN, SRB, SB, J-AL; Writing – Original Draft: MN, SRB, SB, KJS, J-AL; Writing – Review & Editing: MN, SRB, J-AL.

The authors thank all the participants at Ulster University and L V Prasad Eye Institute for taking part in the study.

Online date: July 17, 2019

© 2019 American Academy of Optometry