To describe the lid margin
characteristics of contact lens
wearers and relate them to comfort
during lens wear.
Three study sites enrolled habitual contact lens
wearers. Subjects completed the Comfort
domain of the Contact Lens
User Experience (CLUE) questionnaire, and each eye was graded for the presence of mucocutaneous junction
(MCJ) displacement, lid margin
irregularity, and lid margin
vascularity. Examiners counted the number of meibomian gland (MG) orifices in the central centimeter of the lower eyelid and the number of those that showed pouting/plugging and vascular invasion. MG expressibility was graded according to the Shimazaki schema. Subjects were grouped based on presence/absence of each characteristic, total number of orifices (≥5 vs. <5), and expressibility (grade 0 vs. >0). Descriptive statistics are reported. A linear model was used to assess the fixed effect of each characteristic on combined CLUE score and each CLUE statement, if the effect on combined CLUE score showed p < 0.10.
The study included 203 subjects (67.5% female) with mean age (±SD) of 30.3 ± 9.6 years. The most commonly observed characteristics were orifice pouting/plugging, compromised MG expressibility, and lid margin
vascularity (35.0, 30.3, and 20.4%, respectively). MCJ displacement and MG expressibility had an effect on the combined CLUE score such that individual CLUE statements were analyzed (p = 0.01 and p = 0.06, respectively). MCJ displacement had an effect on comfort
upon insertion (p = 0.01), comfort
after 5 minutes (p = 0.03), end-of-day comfort
(p = 0.01), and ability to maintain ocular moisture (p = 0.030). MG expressibility had a significant effect on general comfort
(p = 0.01), comfort
throughout the day (p = 0.02), and the ability to maintain ocular moisture (p = 0.02).
MCJ displacement and MG expressibility have an effect on contact lens comfort