Purpose. Silicone hydrogel
(SH) lenses are usually replaced after 2 weeks (2W) or 1 month (1M); however, many patients do not comply with the manufacturers' recommended replacement frequency (MRRF). The purpose of this analysis was to investigate the effect of compliance
with MRRF on comfort
in SH wearers.
As a part of a larger study investigating compliance
with MRRF, patients were asked to rate their subjective comfort
from 0 (very poor) to 10 (excellent) in the morning, at the end of the day (EVE), when lenses were new, and needed replacing (NR).
One thousand three hundred forty-four patients wore 2W replacement modality (2WR) (n = 717) or 1M replacement modality (1MR) (n = 617) SH lenses. Comfort
in the morning and when lenses are new were significantly higher than for EVE and NR (p < 0.001). Twenty-nine percent (95% confidence interval 25.3–32.4) of 1MR and 59% (95% confidence interval 55.5–62.7) of 2WR wearers were non-compliant with the MRRF. Compliance
had a significant effect on EVE (p = 0.002, p = 0.008) and NR (p < 0.001, p < 0.001) comfort
. After accounting for compliance
, EVE and NR comfort
and EVE vision
were higher for 1MR than 2WR (p = 0.015, p = 0.044, p = 0.019).
Compliant patients had better EVE and NR comfort
than non-compliant patients, regardless of replacement modality. Optimal subjective performance with SH lenses seems to be facilitated by replacing lenses as recommended.