To investigate the relationship between myopia
and changes in ocular biometry
and macular thickness
in young adults.
Two hundred sixteen eyes from 108 adults (23.3 ± 6.3 years old, mean ± SD) were measured for refractive status, corneal curvature, and axial components of the eye. Macular thickness
was measured in 118 eyes (59 subjects) by optical coherence tomography
. All eyes were categorized into emmetropia, low, moderate, or high myopia
based on the refractive status. Biometric results from right eyes of all subjects were compared between sub-groups with the linear correlation analyzed between refraction and other parameters for each group.
The vitreous chamber depth was longest in high myopia
, followed by the moderate myopia
group, the low myopia
group and finally the emmetropic group (p ≤ 0.004). Average thickness of the inner and outer ring macula in all the myopia
groups was significantly thinner than in the emmetropia group (p ≤ 0.021). Among different macular regions, the inferior quadrant of the outer ring was consistently the thinnest in myopia
. Corneal curvature, anterior chamber depth, and lens thickness measures were not associated with myopia
in young adults is associated with an increase in vitreous length and a decrease in para-foveal thickness. The thinness in the retinal region inferior to the fovea appears to be more highly correlated with myopia
than any other retinal region.