Excessive numbers of the mite, Demodex folliculorum, in the eyelash follicles cause itching and is referred to as demodicosis. We evaluated 4% pilocarpine gel as a treatment for this condition.
An advertisement was placed in a retirement home newsletter, requesting persons with ocular discomfort. Respondents were examined for Demodex and persons with abundant mites were invited to participate. One eye was treated with pilocarpine gel; the other eye was untreated. The relative abundance of mites was evaluated at baseline, after 1 and 2 weeks of treatment. Subjects kept a daily log of symptoms.
Eleven of 22 persons with ocular itching had abundant Demodex. Mites were reduced significantly by the treatment (p=0.017). The amount of mite reduction was closely correlated with the extent to which itching was alleviated (r=0.811, p=0.008).
Abundant Demodex is an important cause of ocular itching in older persons. Mites can be reduced with pilocarpine gel and itching alleviated.
© 1996 American Academy of Optometry