The response ratio
the defining parameter in determining Equivalent Oxygen Percentages (EOP), was calculated for several different test conditions on five subjects with and without the use of a commonly used topical corneal anesthetic (proparacaine 0.25%). In addition, corneal oxygen uptake (microliters per square centimeter per hour) was measured through the respective contact lenses by the method of Fatt and Rasson with and without this anesthetic. In all cases, there was no statistically significant difference found (p < 0.01) between anesthetized and unanesthetized corneas. Therefore, the limited use of a commonly used topical anesthetic in clinical doses appears to be permissible and seems to increase patient comfort and compliance during the procedure.
Received April 14, 1983; revision received July 8, 1983.
* Optometrist, M.S., Member of Faculty, F.A.A.O.
† Optometrist, Ph.D., Member of Faculty, F.A.A.O.
William R. Roscoe
The University of Alabama in Birmingham
The Medical Center/School of Optometry
Birmingham, Alabama 35294
© 1983 American Academy of Optometry