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Novel Use of Porcine Urinary Bladder Matrix in the Exenterated Socket

Wilson, Caroline W. M.D.*; Fisher, Mark T. M.D.; Pagedar, Nitin A. M.D., M.P.H.; Kass, Gretchen A.R.N.P., M.S.N.; Terry, William W. M.D., M.P.H.§; Shriver, Erin M. M.D.*

Ophthalmic Plastic & Reconstructive Surgery: September/October 2019 - Volume 35 - Issue 5 - p e122–e124
doi: 10.1097/IOP.0000000000001453
Case Reports

The aim of exenteration reconstruction is to stabilize the postsurgical wound bed to promote expeditious healing particularly in patients who are undergoing adjuvant radiation and/or chemotherapy. Porcine urinary bladder matrix has previously been used successfully as a wound-healing scaffold in treatment of burns and in acute, chronic, and surgical wounds, but the use of these products has not previously been reported in the exenterated orbit. The authors present a case of the novel use of porcine urinary bladder matrix in a pediatric patient who underwent exenteration for recurrent embryonal rhabdomyosarcoma, subsequent split-thickness skin grafting, and adjuvant radiation.

Porcine urinary bladder matrix was used for primary closure prior to split-thickness skin grafting in the exenterated orbit of a pediatric patient with an aggressive orbital mass, in anticipation of adjuvant proton-beam radiation.

*Department of Ophthalmology and Visual Sciences

Department of Surgery

Department of Otolaryngology

§Department of Pediatrics, University of Iowa Hospital and Clinics, Iowa City, Iowa, U.S.A.

Accepted for publication July 2, 2019.

The authors have no financial or conflicts of interest to disclose.

Address correspondence and reprint requests to Erin M. Shriver, M.D., Carver College of Medicine, University of Iowa, Iowa City, IA. Department of Ophthalmology and Visual Sciences, 200 Hawkins Drive, Iowa City, IA 52242. E-mail:

© 2019 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.