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Development of Poliosis Following Checkpoint Inhibitor Treatment for Cutaneous Melanoma

Ediriwickrema, Lilangi S. M.D.*; Liu, Catherine Y. M.D., Ph.D.*; Kikkawa, Don O. M.D.*,†; Korn, Bobby S. M.D., Ph.D.*,†

Ophthalmic Plastic & Reconstructive Surgery: September/October 2019 - Volume 35 - Issue 5 - p e121–e122
doi: 10.1097/IOP.0000000000001451
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The authors describe a clinical case whereby a patient with metastatic cutaneous melanoma developed eyelash poliosis after undergoing treatment with combination immunotherapy with ipilimumab and nivolumab.

The use of combination delivery of checkpoint inhibitors in treating metastatic or inoperable cutaneous melanoma may result in the development of poliosis as a therapeutic side-effect.

*Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Viterbi Family Department of Ophthalmology, Shiley Eye Institute

Division of Plastic and Reconstructive Surgery, UC San Diego Department of Surgery, La Jolla, California, U.S.A.

Accepted for publication July 8, 2019.

The authors have no conflicts of interest or financial disclosures to declare.

Address correspondence and reprint requests to Bobby S. Korn, M.D., Ph.D., Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Viterbi Family Department of Ophthalmology, Shiley Eye Institute, La Jolla, CA. E-mail: bkorn@ucsd.edu

© 2019 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.