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Bilateral Orbital Compartment Syndrome Preceding Cerebellar Herniation in Neuropsychiatric Systemic Lupus Erythematosus

Hamill, Eric B., M.D.*; Weber, Adam C., M.D.; Patel, Kalyani R., M.D.; Yen, Michael T., M.D.§

Ophthalmic Plastic & Reconstructive Surgery: May/June 2019 - Volume 35 - Issue 3 - p e55–e57
doi: 10.1097/IOP.0000000000001339
Case Reports

Orbital compartment syndrome poses a significant risk for vision loss if not promptly treated. The authors report a patient with neuropsychiatric systemic lupus erythematosus presenting with bilateral orbital compartment syndrome and rapid decompensation leading to uncal and tonsillar herniation. While extremely rare, bilateral orbital compartment syndrome should prompt consideration of systemic etiologies including neuropsychiatric systemic lupus erythematosus.

The authors report a case of bilateral orbital compartment syndrome in the setting of neuropsychiatric systemic lupus erythematosus with evolving cerebellar herniation.

*Eyesthetica, Santa Monica, California

Kaiser Permanente, Atlanta, Georgia

Department of Pathology, Texas Children’s Hospital, Houston, Texas

§Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, U.S.A.

Accepted for publication January 20, 2019.

The authors have no financial or conflicts of interest to disclose.

Address correspondence and reprint requests to Eric B. Hamill, M.D., Eyesthetica, 1513 S. Grand Avenue, #200, Los Angeles, CA 90015. E-mail:

© 2019 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.