Case ReportsCongenital Cranio-Orbital MyofibromaYazici, Bülent M.D.*; Bilge, Ayse Dolar M.D.*; Yazici, Zeynep M.D.†; Yalçinkaya, Ulviye M.D.‡ Author Information Departments of *Ophthalmology, †Radiology, and ‡Pathology, Uludag University, Bursa, Turkey Accepted for publication June 29, 2010. Address correspondence and reprint requests to Bülent Yazici, M.D., Department of Ophthalmology, Uludag University, Bursa, Turkey. E-mail: [email protected] Ophthalmic Plastic & Reconstructive Surgery: July 2011 - Volume 27 - Issue 4 - p e108-e111 doi: 10.1097/IOP.0b013e3181fc05f8 Buy Metrics Abstract A 1-day-old female newborn presenting with a severe left proptosis was found, on imaging, to have a cranial mass extending in both orbits and ethmoid sinuses. Tumor debulking and biopsy were performed through a lateral orbitotomy. Based on histologic findings, a diagnosis of infantile myofibroma was made. No involvement was found in other areas of the body. The patient died because of respiratory arrest after intracranial surgery that was performed 45 days after the orbital surgery. To the authors' knowledge, only one similar case of cranio-orbital myofibroma has been reported previously. This tumor should be considered in the differential diagnosis of congenital proptosis and cranio-orbital tumor. In such cases, tumor debulking can be performed through orbitotomy. ©2011The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.