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Isolated Optic Nerve Infiltration in Systemic Lymphoma—A Case Report and Review of Literature

Kim, Usha R. M.D.; Shah, Akash D. M.D.; Arora, Vipul M.D.; Solanki, Urvashi M.D.

Ophthalmic Plastic & Reconstructive Surgery: July-August 2010 - Volume 26 - Issue 4 - p 291-293
doi: 10.1097/IOP.0b013e3181bd436f
Brief Reports

Ocular involvement in non-Hodgkin lymphoma occurs either as primary ocular, central nervous system lymphoma or isolated intraocular lymphoma. Recurrence of systemic non-Hodgkin lymphoma in the form of CNS lymphoma has been reported. However, recurrence as an isolated optic nerve lesion without involving CNS has never been reported in the pediatric age group. We report a case of systemic diffuse large B-cell lymphoma in a 2-year-old female, which primarily occurred as suprapubic mass and later recurred in the form of isolated optic nerve infiltration, after remission of the primary disease. Early detection and prompt treatment resulted in complete reversal of the disease.

Orbit, Oculoplasty and Oncology Services, Aravind Eye Hospital and Postgraduate Institute Of Ophthalmology, Madurai, Tamil Nadu, India

Accepted for publication August 16, 2009.

The authors claim no financial or proprietary interest in this manuscript.

Address correspondence and reprint requests to Usha R. Kim, D.N.B. Ophthalmology., Orbit, Oculoplasty and Oncology Clinic, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu. E-mail:

©2010The American Society of Opthalmic Plastic and Reconstructive Surgery, Inc.