A 45-year-old woman with BRCA-2 mutation-positive ovarian carcinoma had pain, swelling, and proptosis of her left eye. CT demonstrated a mass in the left orbit. Fine-needle aspiration and lateral orbitotomy were used to obtain tissue for diagnosis. Pathology confirmed poorly differentiated tumor cells consistent with ovarian carcinoma. Cytopathologic testing confirmed receptor and hormonal markers within the orbital specimen that were identical to specimens removed 4 years prior.