Brief ReportsOculoplastic Approach to Treating Barber-Say SyndromeNg, John D. M.D.; Rajguru, Deepali S. M.D.Author Information Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, U.S.A. Accepted for publication November 16, 2005. Supported in part by an unrestricted grant to Casey Eye Institute from Research to Prevent Blindness, New York, New York, U.S.A. The authors have no proprietary interest in this study. Address correspondence and reprint requests to Dr. John D. Ng, Oculoplastics Division, Casey Eye Institute, 3375 SW Terwilliger Boulevard, Portland, OR 97239-4197, U.S.A. E-mail: [email protected]. Ophthalmic Plastic & Reconstructive Surgery: May 2006 - Volume 22 - Issue 3 - p 232-234 doi: 10.1097/01.iop.0000217575.01061.00 Buy SDC Metrics AbstractIn Brief Barber-Say syndrome is a rare dysmorphic disorder with prominent facial involvement. Its primary features include skin, hair, and eyelid abnormalities, the last of which can cause significant ocular symptoms. This report describes a patient with symptomatic corneal exposure secondary to Barber-Say syndrome who benefited from surgical intervention. The patient underwent a bilateral mid-face lift, eyelid repositioning and reconstruction, botulinum toxin application, and acellular dermis grafting. Surgical exploration revealed dysfunctional features of the external and internal eyelid anatomy not previously described with this condition. Improvement was noted in overall facial symmetry and appearance. In addition, the patient noted increased comfort after the resolution of dry eye symptoms and exposure keratopathy. Barber-Say syndrome is a rare disorder for which an oculoplastic approach to reconstructive therapy can significantly improve related disfigurement and discomfort. ©2006The American Society of Opthalmic Plastic and Reconstructive Surgery, Inc.