A 65-year-old woman received injections of Restylane, cross-linked hyaluronic acid, for the intended cosmetic filling of periorbital rhytids. The achieved result was undesirable, and the filler lasted more than 5 years. Hyaluronidase administered directly beneath the treated areas resulted in rapid resolution of the Restylane effect.
Hyaluronidase reversed a long-standing, undesirable effect of Restylane injections.
Plastic Eye Surgery Associates, PLLC, Houston, Texas, U.S.A.
Accepted April 30, 2004.
The authors have no direct financial interest in any of the products discussed herein.
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